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-X-C chemokine family, the members of which have conserved cysteine motifs at the amino terminal end. Interleukin-8, a potent chemoattractant for neutrophils both in vitro and in vivo, is produced by numerous cells, including alveolar macrophages, monocytes

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in American Journal of Veterinary Research

prototype. 40 Interleukin 17A, the cytokine examined in the study reported here and that we shall refer to as IL-17, is a glycoprotein localized to T cells (CD4+ and CD8+ cells), neutrophils, and eosinophils. 39 Analysis of the data from our study

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in American Journal of Veterinary Research

dogs with BAOS, compared with values in the control dogs. Interleukin-17 has been characterized as a proinflammatory cytokine that acts on a variety of tissues. In chronic inflammatory processes associated with the respiratory tract in humans, such as

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in American Journal of Veterinary Research

.16. Interleukin-4 was not detectable in BALF of any cat in the CLIN ASM group, regardless of whether they were receiving glucocorticoids (n = 6 cats) or not (7). Interferon-γ was detected in only 1 cat in the CLIN ASM group, and that cat was being treated with

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in American Journal of Veterinary Research

decrease susceptibility to influenza and reduce the severity of annual outbreaks. ABBREVIATIONS T H T-helper IL Interleukin BALF Bronchoalveolar lavage fluid TNF-α Tumor necrosis factor-α C T Threshold cycle

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in American Journal of Veterinary Research

Houde for technical assistance. ABBREVIATIONS BAL Bronchoalveolar lavage GAPDH Glyceraldehyde-3-phosphate dehydrogenase IL Interleukin LPS Lipopolysaccharide TNF Tumor necrosis factor Footnotes a. RHT-Infodat, RHT-INFODAT INC

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in American Journal of Veterinary Research

-affected horses and has been correlated with clinical disease. 29,30 ABBREVIATIONS GAPDH Glyceraldehyde 3-phosphate dehydrogenase IL Interleukin MEM Minimum essential medium NF-κB Nuclear factor κ-light-chain-enhancer of activated B cells PAS

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in American Journal of Veterinary Research

several inflammation-associated cytokines (eg, tumor necrosis factor-A; transforming growth factor-B; and interleukin-B, -6, -8, and -10) and acute phase proteins (eg, C-reactive protein and haptoglobin) are increased in obese mice as well as in people. 23

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in American Journal of Veterinary Research

transporters, and cyclophilin, 9 which were not investigated in the present study. Furthermore, EMMPRIN is regulated by various factors related to inflammation, including tumor necrosis factor-α and interleukins. 27,28 Interestingly, EMMPRIN may also self

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in American Journal of Veterinary Research

injury. It also stimulates synthesis of tumor necrosis factor-α, interleukin-1, and interleukin-6. Glucose-6-phosphate isomerase induces B-cell–dependent chronic inflammation 23 and promotes expression of proangiogenesis genes to prepare tissues for

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in American Journal of Veterinary Research