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has been shown to inhibit glutathione reductase, suggesting decreases in reduced glutathione levels. 20 Decreases in concentrations of endogenous antioxidants, such as glutathione, have been implicated in the development of drug-induced liver injury

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in American Journal of Veterinary Research

osteosarcoma in dogs have been performed, no reports of the radiosensitivity of canine osteosarcoma cell lines or their capacity to repair radiation-induced injury have been published, to our knowledge. Such background information is necessary to determine the

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in American Journal of Veterinary Research

; bar = 200 μm. Discussion In the present study, MWA-UP induced macroscopic subtotal thermal necrosis (ablation) in prostate glands ranging in size from 3.0 to 54.8 cm 3 in canine cadavers while limiting urethral mucosal injury

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in American Journal of Veterinary Research

injury by increasing urinary excretion. The characteristics of the HA-Pt formulation could allow investigation of its efficacy in treatment of dogs with malignant tumors, and the results could offer information relevant to human medicine, with a potential

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in American Journal of Veterinary Research

Implant-associated sarcoma of the proximal region of the tibia in dogs with a history of TPLO 1 treatment for cranial cruciate ligament injury has been proposed to be more common than naturally occurring sarcoma. 2,3 Implant-associated sarcoma

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in American Journal of Veterinary Research

marrow progenitor cells into cycling and differentiation prior to a cytotoxic treatment will increase their susceptibility to injury and exacerbate myelosuppression. 69 However, it has also been reported 34,54,58,70–76 that hematopoietic stimulation

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in American Journal of Veterinary Research

time of death 39 days later due to acute kidney injury. Necropsies were not performed on any of the cats. Discussion Our analysis of early clinical experiences with an SRS protocol for treatment of cats with insulin resistance and acromegaly

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in American Journal of Veterinary Research

growth and stress on limbs, with injury to sensitive cells, are often cited as possible reasons for bone tumor formation. The radiographic appearance of these tumors typically indicates concurrent cortical bone lysis and proliferation within the lesion

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in American Journal of Veterinary Research

In infectious, traumatic, neoplastic, immune-mediated, and inflammatory processes, organisms develop a general, nonspecific, acute reaction to local or systemic injuries that affects homeostasis. This reaction is known as the acute-phase response

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in American Journal of Veterinary Research

experimental liver resections and injuries to large veins . Ann Surg 1946 ; 124 : 952 – 961 . 10.1097/00000658-194611000-00010 20. Hsu YH , Chen DW , Tai CD , et al. Biodegradable drug-eluting nanofiber-enveloped implants for sustained release

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in American Journal of Veterinary Research