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similar age were used as controls. All cats were initially housed in stainless steel cages in the animal colony and allowed to acclimate to their environment for at least 3 months. Cats received a diagnosis of FIC or were deemed healthy on the basis of

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in American Journal of Veterinary Research

intact females, and 1 spayed female) of similar age were used as controls. Cats were housed in stainless steel cages in the animal colony and allowed to acclimate to the environment for at least 3 months. All experimental procedures were approved by The

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in American Journal of Veterinary Research

-selective environment theory, which proposes that previous antimicrobial use creates an environment within the urinary bladder that allows the growth of low levels of antimicrobial-resistant bacteria, such as enterococci, by elimination of competing bacteria that were

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in American Journal of Veterinary Research

diagnosable cause. Clinical signs of IC in cats may result from multiple abnormalities of the urinary bladder, CNS, and hypothalamic-pituitary-adrenal axis. 7 It has been suggested that changes in several factors (eg, changes in environment, reduction in

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in American Journal of Veterinary Research

collection. The first voided urine sample in the morning was collected via free catch in the home environment for each dog; blood was collected in the clinic from a cephalic vein in 1.3-mL lithium-heparin tubes. d Plasma was prepared by centrifugation of

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in American Journal of Veterinary Research

1999 ; 67 : 295 – 299 . 10.1053/rvsc.1999.0336 21. Blauch B . Spinal reflex walking in the dog . Vet Med Small Anim Clin 1977 ; 72 : 169 – 173 . 22. R Development Core Team . R: A language and environment for statistical computing . Vienna

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in American Journal of Veterinary Research

a humidified environment. The wells were washed 4 times with 400 ML of wash buffer (TBSST)/well, blocked for 1 hour with TBS and 0.5% bovine serum albumin (100 ML/well), and washed again as previously described. A rabbit polyclonal antibody that

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in American Journal of Veterinary Research

-controlled environment; fed 125 kcal/kg 0.75 of a maintenance feed 17 , a formulated for dogs (which contained 26% protein, 16% fat, 3% fiber, 12% moisture, 1.3% salt, 1.0% calcium, and 0.8% phosphorus on a dry-matter basis) once daily; and allowed free access to water

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in American Journal of Veterinary Research