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, the purpose of the study reported here was to evaluate SP-D concentrations in the serum and BALF of young healthy horses on pasture and in a typical barn environment. Materials and Methods Horses Twenty young healthy horses from a research

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in American Journal of Veterinary Research

injury associated with RAO, with potential for use in the diagnosis and monitoring of this disease. 7–10 The airspace epithelial surface of the lung is particularly vulnerable to oxidant damage as it directly contacts the environment. 11,12 Activated

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in American Journal of Veterinary Research

surfactant aggregate ratio, 17 and changes in the ratio between PC and PG, the 2 main phospholipid classes of surfactant. 16,17 Changes in surfactant composition and function that develop as a result of short-term exposure to a challenge environment have

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in American Journal of Veterinary Research

change in environment and administration of bronchodilators, 1 included 4 mares and 3 geldings, with a mean age of 21.0 ± 6.4 years and mean body weight of 503 ± 36 kg. All horses were maintained on pasture and received a supplemental pelleted diet

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in American Journal of Veterinary Research

exacerbation-remission cycle of the disease. Identification of environmental factors, particularly those that precede the onset of clinical signs, would prompt the removal of horses from the environment during periods of high risk, even if the triggering agents

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in American Journal of Veterinary Research

to obtain. Cells and antibodies exiting the lung through the efferent lymphatic duct ultimately reach the systemic circulation but only after dilution. Thus, serum composition is less reflective of the pulmonary environment than efferent lymph

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in American Journal of Veterinary Research

instrumentation was completed, ventilation was initiated for a 24-hour period in the ICU setting to mimic a clinical environment. Dogs administered drugs in accordance with protocol 1 (BMM group) received a CRI of a benzodiazepine (diazepam i [n = 3 dogs] or

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in American Journal of Veterinary Research

signs of disease, no signs of airway inflammation, and no changes in results of lung function tests. Phospholipid concentrations in surfactant decreased further when asthmatic horses were moved into an environment and exposed to dusty hay and straw

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in American Journal of Veterinary Research

condition score of 5 out of 9 (body weight, 100 to 204 kg) were included in this study. None of the llamas had been previously exposed to pulmonary function testing or a laboratory environment. Following hospital admission in the morning, the llamas were

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in American Journal of Veterinary Research

. During acute RSV infection in human infants, experimental infection in mice, and BRSV infection in calves, chemokines, cytokines (Th2), and inflammatory cells increase in the lungs, which creates an environment that facilitates antigen presentation and

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in American Journal of Veterinary Research