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most common clinical manifestation of acromegaly in cats is insulin-resistant diabetes mellitus. 2 Notably, cats with acromegaly tend to gain weight, in contrast to the weight loss typically observed in cats with unregulated diabetes mellitus that do

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in American Journal of Veterinary Research

, but serious adverse effects (including allergic reactions and nephrotoxicosis) have been reported rarely. 29–33 Predisposing factors for nephrotoxicosis include underlying renal disease, diabetes mellitus, NSAID use, and hypotension. 29–31 For humans

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in American Journal of Veterinary Research