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results of physical and laboratory examinations; blood glucose concentrations were within the reference range. Blood samples were collected during routine health examinations. Cats with diabetes mellitus —Seven cats with DM were enrolled in the study

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in American Journal of Veterinary Research

The use of several insulin preparations, including SC administration of NPH insulin for dogs with uncomplicated diabetes mellitus and IV administration of lispro insulin for dogs with diabetic ketoacidosis has been described. 1,2 However, a

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in American Journal of Veterinary Research

were also collected from 13 client-owned diabetic dogs. Diabetes mellitus was diagnosed on the basis of clinical signs (eg, polyuria and polydipsia, weakness, and weight loss) and an unfed BG concentration > 200 mg/dL combined with glycosuria. Eight

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in American Journal of Veterinary Research

Many similarities exist between type 2 diabetes mellitus in cats and in humans. 1,2 Both conditions typically have an onset in middle age or later, are associated with obesity, and are characterized by defective insulin secretion, insulin

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in American Journal of Veterinary Research

concentrations of progesterone. 1 Some dogs also secrete large amounts of GH from the mammary gland during diestrus in response to endogenous progesterone. 2,3 Both progesterone and GH induce insulin resistance and may potentially cause diabetes mellitus in the

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in American Journal of Veterinary Research

However, diabetes mellitus was the most common concurrent disease in a retrospective study 2 of dogs with hypothyroidism, and hypothyroidism was one of the most commonly diagnosed concurrent disorders in dogs with diabetes mellitus. 3 Findings in dogs

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in American Journal of Veterinary Research

Obese dogs, like obese humans, have components of the metabolic syndrome such as insulin resistance. 1 However, type 2 diabetes mellitus, an obesity-associated disease, has not been rigorously documented in dogs. 2 Type 2 diabetes mellitus

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in American Journal of Veterinary Research

Obesity, which is defined as an accumulation of excess body fat, is the most common nutritional disorder in small animals and is associated with various diseases such as diabetes mellitus, pancreatitis, cardiovascular disease, arthropathies, and

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in American Journal of Veterinary Research

,4,6 hyperosmolar disorder, 7 and diabetes mellitus. 8 Interestingly, camelids are also susceptible to disorders of fat metabolism, such as hepatic lipidosis, 9,10 hyperketonemia, 9,11 high concentrations of circulating nonesterified fatty acids, 9 and

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in American Journal of Veterinary Research

development of hyperglycemia in human patients with type 2 diabetes mellitus. 17 Human patients with type 2 diabetes mellitus develop β-cell hypertrophy and hyperplasia early in the disease process, followed by β-cell loss as the disease progresses. 18 In

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in American Journal of Veterinary Research