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. Exploratory celiotomy was declined by the owner. Treatment with flunixin meglumine (1 mg/kg, IV, q 12 h), potassium penicillin (22,000 U/kg [10,000 U/lb], IV, q 6 h), and gentamicin (6.6 mg/kg [3.0 mg/lb], IV, q 24 h) was initiated. A CBC was repeated 3 days

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in Journal of the American Veterinary Medical Association

celiotomy was performed. The contents of the abdominal cavity were grossly normal except for a large, approximately 4-to 5-cm left lateral liver tumor. Multiple nodules were present diffusely throughout the liver, with the largest being approximately 0.8 cm

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in Journal of the American Veterinary Medical Association

tissue removed during celiotomy. 1 Treatment and assessments —Initial trilostane dosage for each dog was 0.5 to 2.5 mg/kg (0.23 to 1.14 mg/lb) administered orally every 12 hours. Capsules provided by the manufacturer (30, 60, and 120 mg) were used

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in Journal of the American Veterinary Medical Association