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complications, such as ruminal bloating, regurgitation, and aspiration, following general anesthesia in the caprine species. 2 Local anesthetics, such as lidocaine (LIDO) and bupivacaine (BUPI), provide excellent analgesia, are cost effective, and are readily

Open access
in American Journal of Veterinary Research

improper catheter placement, local edema formation, infection, pain, and lameness. 5 , 6 Investigation of novel pharmacologic agents, such as extended-release (liposomal encapsulated) bupivacaine offers hope for improved analgesia. 7 Liposomal

Open access
in American Journal of Veterinary Research

other than lidocaine may be advantageous for RB in horses. Mepivacaine, for example, induces less local vasodilation than lidocaine, which may enhance its duration of action and potency in tissue. 7 Bupivacaine is more lipid soluble and protein bound

Full access
in Journal of the American Veterinary Medical Association

of epidural anesthesia performed with bupivacaine alone or with fentanyl or sufentanil in bitches maintained at a light plane of anesthesia with continuous infusion of propofol. Materials and Methods Animals —Thirty female dogs of different

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in Journal of the American Veterinary Medical Association

abdominal surgery in humans. 3–12 According to meta-analyses and systematic reviews, IP administration of bupivacaine currently is recommended for laparoscopic surgery in humans as an adjuvant analgesic technique. 3,13–16 Intraperitoneal administration of

Full access
in American Journal of Veterinary Research

placing and maintaining an epidural catheter. 8–10 Additionally, epidural injection of anesthetics may result in inadvertent recumbency of the patient. 11 A liposomal formulation of bupivacaine sustains release of bupivacaine via slow degradation of

Full access
in American Journal of Veterinary Research

, neoplasia, and penetrating ocular injuries. Local anesthesia is an important component of multimodal pain control for patients undergoing enucleation. Agents such as bupivacaine block sodium channels, thus preventing depolarization of the nerve, action

Free access
in Journal of the American Veterinary Medical Association

Bupivacaine is an amide local anesthetic with an intermediate onset of action, a high potency because of its lipid solubility, and a long duration of action. When local anesthetics are combined with systemic analgesics, lower doses of systemic

Full access
in American Journal of Veterinary Research

standard local anesthetics is their limited duration of action. A study comparing lidocaine to bupivacaine for incisional and IP analgesia suggested that longer-acting local anesthetics are preferable, but even standard local anesthetics that last several

Full access
in Journal of the American Veterinary Medical Association

administered to provide analgesia, local anesthetics block the sensory transmission of noxious stimuli and can provide perioperative pain control. 4 Bupivacaine hydrochloride is the longest-acting local anesthetic commonly used in horses. When bupivacaine

Full access
in American Journal of Veterinary Research