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inflammatory diseases, including sepsis, atherosclerosis, and tumorigenesis. 1 Platelet-activating factor–induced inflammation has not been fully characterized in dogs. In humans, PAF-mediated inflammation has been analyzed in the skin 12–16 because PAF is a

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in American Journal of Veterinary Research

A role for platelets as inflammatory cells is being increasingly recognized in multiple diseases of humans. 1 Thus, it has been suggested that pathologic platelet activation may contribute to atherosclerosis; ischemic heart disease; diabetes

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in American Journal of Veterinary Research

regenerating endothelial cells express P-selectin in atherosclerosis-prone apolipoprotein E-deficient mice . Am J Pathol 2005 ; 167 : 1511 – 1518 . 10.1016/S0002-9440(10)61237-0 55. Kalsch T Elmas E Nguyen XD , et al. Endotoxin-induced effects

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in American Journal of Veterinary Research