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–related complications including vascular disease, retinopathy, and glomerulopathy. 7–10 Dogs with diabetes mellitus are also at risk for some of these long-term complications. Although atherosclerosis is not frequently diagnosed in dogs, dogs with atherosclerosis are

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in American Journal of Veterinary Research

positively correlated with serum high-density lipoprotein concentration. Unlike humans, atherosclerosis is uncommon in dogs, and dogs with atherosclerosis are more likely to also have other illnesses such as diabetes mellitus and hypothyroidism, compared with

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in American Journal of Veterinary Research

atherosclerosis in diabetes . Atherosclerosis 2003 ; 168 : 263 – 269 . 10.1016/S0021-9150(03)00140-0 52. Asplin KE , Sillence MN , Pollitt CC , et al. Induction of laminitis by prolonged hyperinsulinaemia in clinically normal ponies . Vet J 2007

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in American Journal of Veterinary Research

; 26 : 201 – 209 . 10.1080/03079459708419206 42. Hass GM Trueheart RE Hemmens A . Experimental atherosclerosis due to hypervitaminosis D . Am J Pathol 1960 ; 37 : 521 – 549 . 43. Capen CC Cole CR Hibbs JW . The pathology of

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in American Journal of Veterinary Research

035003 5. Bonomini F Tengattini S Fabiano A , et al . Atherosclerosis and oxidative stress . Histol Histopathol 2008 ; 23 : 381 – 390 . 6. Shao B Oda MN Oram JF , et al . Myeloperoxidase: an inflammatory enzyme for

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in American Journal of Veterinary Research

'Agostino R Jr , Karter AJ , et al. Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study . JAMA 1998 ; 279 : 669 – 674 . 10.1001/jama.279.9.669 37. Cocks M , Shaw CS

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in American Journal of Veterinary Research