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,177 humans and then followed changes in LBM for 5 years. That study revealed that higher concentrations of inflammatory markers, including CRP, interleukin-6, and TNF-α were associated with a greater 5-year decrease in LBM, compared with humans with decreased

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in American Journal of Veterinary Research

, cachexia, and critical illnesses. 13 Muscle atrophy can also occur in inherited and acquired myopathies and neuropathies. Triggering signals of muscle wasting include proinflammatory cytokines (TNF-α, IL-1β, and IL-6) that are potent activators of NFκB

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in American Journal of Veterinary Research

quantitative real-time PCR analysis was performed. Real-time PCR assay —The mRNA expression of cytokines (IFN-γ, IL-1β, IL-6, TNF-α, and IL-10) was measured in cDNA samples with equine-specific intron-spanning primer and probe sets, 37 as described. 36 The

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in American Journal of Veterinary Research