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Summary

Bronchoalveolar lavage (bal) fluid was analyzed in healthy horses, using different lavage fluid volumes and lung sites. The only significant difference in the cellular composition of bal fluid between the right and left lungs was the mast cell numbers, which were significantly higher in the left lung. Total cell count ranged from 34 to 330 cells/μl for the right lung and 43 to 330 cells/μl for the left lung. Percentage of neutrophils ranged from 1 to 7% in the right lung and 1 to 5% in the left lung. The small-volume (50 ml) lavage had a greater percentage of neutrophils and a lesser percentage of mast cells in the large-volume (350 ml) lavage. Statistical difference in the composition of bal fluid recovered was not detected between the 3 sequential 100-ml lavages and a single 300-ml lavage, except that macrophages were significantly higher in the 3 sequential 100-ml lavages. Values for bal fluid analysis in healthy horses have varied considerably and this variation is from a failure to adhere to any standard technique for volume of fluid infused.

Free access
in American Journal of Veterinary Research
in Journal of the American Veterinary Medical Association

Summary

Bronchoalveolar lavage was performed in 22 horses with pneumonia or pleuropneumonia. All horses had clinical evidence of pneumonia or pleuropneumonia on the basis of physical, radiographic, ultrasonographic, tracheobronchial aspirate or postmortem findings. Results of lavage fluid analysis were normal in 9 horses, equivocal in 3 horses, and abnormal in 10 horses. Abnormal lavage fluid had increased total cell count, increased relative and absolute neutrophil counts, degenerative neutrophils, and decreased relative and absolute macrophage and lymphocyte counts.

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in Journal of the American Veterinary Medical Association

Summary

Bronchoalveolar lavage (bal) was performed on 16 horses to determine whether it caused local or diffuse inflammation in the lungs. In 7 horses, bal was performed in both lungs twice, 48 hours apart. Although total cell counts of the bal samples did not change significantly, there were increased numbers and percentage of neutrophils in the second lavage fluid samples. In 5 horses, bal was performed in 1 lung and repeated 48 hours later in the same lung and in the corresponding airway in the contralateral lung. The absolute cell count and percentage of neutrophils were significantly (P = < 0.05) increased in the second sample from the lung that was lavaged twice. In 4 horses, bal was performed in 1 lung and 48 hours later, repeated in an adjacent airway to the first bal site, and in the corresponding airway in the contralateral lung. Significant differences were not detected the total or differential cell counts of the bal fluid recovered at any time, except for an increase in neutrophil percentage in the second sample in the contralateral lung. The increased neutrophil percentage values were within the range of normal for healthy horses.

Results of the study suggested that, in horses, bal induces a localized pulmonary neutrophil influx that persists at least 48 hours and is characterized by a relative and absolute increase in the number of neutrophils in the lavage fluids.

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in American Journal of Veterinary Research

epistaxis after exercise. Sample collection and analysis Bronchoalveolar lavage fluid and blood samples were collected from the endurance horses at 3 to 8 days and 36 to 38 days after the race (samples A and B, respectively). Sample B served as a

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in Journal of the American Veterinary Medical Association

elicitation of cough, were recorded on a score sheet. To minimize discomfort and coughing during airway examination and bronchoalveolar lavage, 60 to 180 mL of warm saline solution containing 2 mg of lidocaine i /mL was instilled as needed into the trachea, at

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in American Journal of Veterinary Research

disease was not detected via physical examination or thoracic radiography were included if they had radiographic evidence of airway or pulmonary parenchymal disease and underwent bronchoalveolar lavage with cytologic examination and bacterial culture of a

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in Journal of the American Veterinary Medical Association

lavage BALF Bronchoalveolar lavage fluid HST High-speed treadmill IAD Inflammatory airway disease IL Interleukin a. CIBA-GEIGY 288 BG, Norwood, Mass. b. Classic 4000 High-Speed Equine Treadmill, Walmanik International, Ereedom, Pa. c

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in Journal of the American Veterinary Medical Association