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It is well-known that perinatal infections and PAS are the major causes of morbidity among equine neonates. An in-depth understanding of the pathophysiology of these diseases could help generate new diagnostic and prognostic tools that would have

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in American Journal of Veterinary Research

against various microorganisms, 3,4 including intracellular bacteria such as MAP. 5 Antimicrobial activity of Ga was also reported for a study 6 in which neonatal calves prophylactically treated with GaN before and after challenge-exposure with a live

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in American Journal of Veterinary Research

Virulent and toxigenic Escherichia coli strains are responsible for a number of diseases in humans and other animals, ranging from diarrhea in children and neonatal livestock to life-threatening extraintestinal infections. In humans, strains of

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in American Journal of Veterinary Research

anesthetized neonatal foals. Materials and Methods Animals —Six neonatal foals between 1 and 3 days of age and weighing between 38 and 45 kg were used in the study. Each foal had a normal birth and was determined to be healthy on the basis of results of

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in American Journal of Veterinary Research

described, 7,8 and CT is also considered superior to standard radiography for the detection of pathological changes within the lungs. 9–13 In hospitalized neonatal foals, for which respiratory tract disease significantly impacts patient morbidity and

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in American Journal of Veterinary Research

Cardiovascular depression is commonly encountered in anesthetized neonatal foals and in foals with sepsis, perinatal asphyxia, or both. 1 Cardiovascular monitoring in neonatal foals usually includes any or all of the following parameters: heart

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in American Journal of Veterinary Research

Introduction Neonatal morbidity and mortality are major causes of economic loss for US beef cattle producers. 1 In 2017, the majority of US beef operations (51.2%) had at least 1 calf that was born alive but died or was lost prior to weaning

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in Journal of the American Veterinary Medical Association

, and relative humidity were obtained for use in the study. Determination of neonatal IgG1 status —A blood sample was collected from a jugular vein of each calf between 24 and 72 hours after birth. This time period for blood collection was selected to

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in Journal of the American Veterinary Medical Association

Neonatal foals are immunocompetent but immunologically naïve at birth. 1,2 Immediately after birth, production of autogenous immunoglobulins commences in response to antigen exposure, but substantial immunoglobulin concentrations are not achieved

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in Journal of the American Veterinary Medical Association

Summary

Serum concentrations of cefotaxime and desacetylcefotaxime were measured in 1-week-old pony foals after iv administration of a single dose of cefotaxime.

The cefotaxime disposition data conformed to a two-compartment model with elimination half-life of 0.60 hour. The combined cefotaxime and desacetylcefotaxime data was best described by a four-compartment model. The apparent half-life describing the disappearance of desacetylcefotaxime was 1.69 hours.

Dosage of 40 mg/kg of body weight given iv every 4 to 6 hours for neonatal foals with gram-negative septicemia and every 2 hours for foals with meningitis is recommended for further study.

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in American Journal of Veterinary Research