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insufficient to maintain erythropoiesis. 24–26 Lemur species are suspected to be prone to absorption of high amounts of iron from the gastrointestinal tract, so the lack of response to oral supplementation was unexpected; however, inhibition of iron absorption

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in Journal of the American Veterinary Medical Association

endurance exercise and, by extension, the contribution of such changes to decreases in PCV will likely require measurement of plasma volume by means of dye dilution methods. Reduced erythropoiesis is unlikely to account for the decrease in RBC count, in that

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in Journal of the American Veterinary Medical Association

. However, the pathogenesis of PIMA is unclear. The condition is characterized by nonregenerative anemia, ineffective erythropoiesis, and, in most affected dogs evaluated at the authors’ institution, rubriphagocytosis, which is the phagocytosis of intact

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in American Journal of Veterinary Research

availability for erythropoiesis. 41–43 In the present study, metarubricytosis (identified in 11/31 [35%] cats) was even more common than anemia. To our knowledge, this finding has not been reported previously in cats with sepsis. Generally, metarubricytosis in

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in Journal of the American Veterinary Medical Association

clinically significant nonregenerative anemia. 14 , 15 Anemia secondary to CRD is a result of decreased production of kidney-associated erythropoietin (EPO), the principal hormonal regulator of erythropoiesis. Spliced feline EPO (feEPO) mRNA is 579

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in American Journal of Veterinary Research

reticulocytosis is the hallmark of intensified erythropoiesis in the bone marrow 3,7–9 Low numbers of reticulocytes (1% of RBCs or < 60,000 to 65,000 reticulocytes/μL) are expected in healthy nonanemic dogs. 1,8 In anemic dogs with regeneration, increased

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in Journal of the American Veterinary Medical Association

Transfusion of packed RBC units is performed commonly in hospitalized dogs with anemia caused by hemorrhage, hemolysis, or ineffective erythropoiesis. 1,2 Some veterinary studies have associated blood administration with complications, including

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in Journal of the American Veterinary Medical Association

erythropoiesis in dogs, but a decrease to 25% of normal renal mass may not be sufficient to maintain adequate erythropoietin synthesis. 16 Although none of the donor dogs had a decrease in Hct, RBC count, or other hematologic variables, significant differences

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in Journal of the American Veterinary Medical Association

erythroblasts and megakaryocytes have been mostly described with FIV and FeLV infections, as well as with feline parvovirus infections. 5 Among these diseases, FeLV infection in particular can cause selective suppression of erythropoiesis and thrombocytopenia

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in Journal of the American Veterinary Medical Association

certain differences between avian and mammalian erythroid cell maturation. In birds, erythropoiesis occurs in the bone marrow primarily, although a large proportion of the maturation of the erythroid cell series may occur intravascularly, especially in

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in Journal of the American Veterinary Medical Association