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Three 6-week-old pigs were submitted alive for necropsy to the Animal Disease Diagnostic Laboratory at Purdue University. The pigs were from a farm that operated a multisite production system, with a farrowing site and a wean-to-finish site. Among the 4,400 pigs at the wean-to-finish site, there was an outbreak of illness with estimated morbidity rate of 20% and estimated mortality rate of 8%. Pigs at the wean-to-finish site had been born within 2.5 weeks of each other and had been weaned at 3 weeks of age. The 3 pigs submitted (all 6 weeks old) for euthanasia and necropsy were

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in Journal of the American Veterinary Medical Association
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A 7-week-old 9.6-kg (21.1-lb) female Yorkshire pig was submitted for euthanasia and necropsy to the Animal Disease Diagnostic Laboratory at Purdue University. The pig was from a group of 30 Yorkshire pigs that had been weaned 4 weeks prior but had never thrived, with some pigs having developed diarrhea and coughing. In the 2 days prior to submission of the pig, 5 other pigs in the group developed clinical signs including shivering, lethargy, dyspnea, and staggering that progressed to paddling and death within 12 to 14 hours. Some of the affected pigs had swollen eyelids. The antemortem clinical signs

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in Journal of the American Veterinary Medical Association
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An 18-year-old sexually intact male ball python (Python regius) housed at a local Indiana zoo was found moribund without prior clinical signs and was transported to the Animal Disease Diagnostic Laboratory at Purdue University. On arrival at the diagnostic laboratory, the snake was alive, yet extremely lethargic; it was placed in a carbon dioxide–filled chamber until completely immobile and unresponsive followed by decapitation prior to necropsy.

Clinical and Gross Findings

Caretakers of the snake did not note any clinical signs prior to the sudden onset of lethargy. At necropsy, the snake was lean with atrophied fat bodies;

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in Journal of the American Veterinary Medical Association
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A 10-year-old 24.6-kg (54.1-lb) spayed female German Shepherd Dog mix was evaluated because of signs of cervical pain of 1 month's duration and acute left pelvic limb lameness of 5 days’ duration.

Clinical and Clinicopathologic Findings

Physical examination revealed signs of pain during left tarsal joint manipulation and an enlarged left popliteal lymph node. Mild to moderate effusion was evident in the left tarsal region (Figure 1). Neurologic examination findings were considered normal other than signs of pain that were elicited on palpation of the midcervical region. Radiography revealed no obvious cervical abnormalities; however, mild thickening of

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in Journal of the American Veterinary Medical Association
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Two aborted fetuses (A and B) from a 4-year-old ewe were submitted for an abortion evaluation. Fetuses A and B had a crown-to-rump length of 41.8 cm and 42.5 cm, respectively, indicating a gestational age each of approximately 19 to 21 weeks. This ewe was from a group of approximately 40 ewes. In this flock, 3 other ewes aborted; 1 ewe aborted midgestation and the other 2 ewes aborted around the same date and stage of gestation as this ewe. Another ewe in this flock gave birth to twins, one of which was stillborn and one that was weak

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in Journal of the American Veterinary Medical Association
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A 6.5-year-old 10-kg (22-lb) castrated male mixed-breed dog was referred for evaluation of persistent lethargy, vomiting, thrombocytopenia, anemia, and pyrexia of approximately 1 month's duration. Treatments administered prior to referral included oral administration of the antiemetic metoclopramide hydrochloride (0.5 mg/kg [0.23 mg/lb], q 12 h) and amoxicillin (25 mg/kg [11.4 mg/lb], q 12 h) for 1 week, followed by oral administration of prednisone (2 mg/kg [0.9 mg/lb], q 12 h) for 1 week. Intermittent seizures began during treatment with prednisone; the frequency of drug administration was decreased (2 mg/kg, q 24 h) 3 days prior to referral.

Clinical and
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in Journal of the American Veterinary Medical Association
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A 2.5-year-old 62.6-kg (137.7-lb) pregnant female Huacaya alpaca was evaluated because of a mass associated with its left shoulder region. The mass was first detected 1 month prior and had doubled in size in the intervening period. The owners had not noted it to cause signs of pain, cause lameness, or affect the alpaca's eating or locomotion. There was no known traumatic event preceding the appearance of the mass. No other animals on the farm had similar lesions currently or in the past. The alpaca was reported to be in its 10th month of gestation, as determined on the

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in Journal of the American Veterinary Medical Association