To describe findings, determine the rate of survival to hospital discharge, and identify prognostic indicators of poor outcomes for female cats (queens) with pyometra treated with ovariohysterectomy (OHE) in a nonspecialized setting.
134 queens with pyometra diagnosed between January 1, 2017, and December 31, 2019.
The medical records were retrospectively searched and data including patient history, clinical signs, blood work results, and outcome (survival to hospital discharge, length of hospitalization, and uterine rupture) were collected from medical records. Logistic regression models were used to assess potential predictors of outcomes.
Dehydration (69% [83/121]) and absolute neutrophilia (83% [52/63]) were commonly reported. The rate of survival to hospital discharge was 100% (126/126; 95% CI, 97% to 100%) for queens treated with OHE; 33% (41/126) were hospitalized ≥ 2 nights, and 4% (5/120) had uterine rupture. Queens with abnormal serum ionized calcium concentration or signs of depressed mentation had greater odds (OR of 4.64 and 2.26, respectively) of ≥ 2 nights’ hospitalization. Queens with high rectal temperature, closed pyometra, or heart murmur had greater odds (OR of 35.66, 17.37, or 16.06, respectively) of uterine rupture.
Our findings indicated that OHE for pyometra in queens was highly successful even when performed in a nonspecialty hospital with high-quality basic supportive care, and we believe most general practitioners who offer OHE could expect to see similar outcomes. With more general-practice veterinarians comfortable treating pyometra in their clinics, OHE for pyometra will be available to more pets, ultimately saving more lives.
To determine the rate of survival to hospital discharge and identify indicators associated with poor outcomes among female dogs (bitches) with pyometra treated with ovariohysterectomy (OHE) in a nonspecialized setting.
405 bitches diagnosed with pyometra at the American Society for the Prevention of Cruelty to Animals Animal Hospital from January 1, 2017, to February 8, 2019.
For this retrospective study, medical records were searched and data collected including patient history, clinical signs, serum biochemical analyses results, and outcome (survival to hospital discharge, length of hospital stay, and uterine rupture). Logistic regression models were used to assess multivariable associations and identify potential predictive variables.
The rate of survival to hospital discharge for bitches with pyometra treated with OHE was 97% (394/405); 44% (174/394) stayed in the hospital ≥ 2 nights, and 3% (11/390) had a ruptured uterus. Bitches with a high BUN concentration or heart murmur had greater odds of death after OHE; however, the model had low predictive power. Those with uterine rupture, inappetence, high concentrations of BUN or serum creatinine, low PCV, or dehydration had greater odds of hospitalization ≥ 2 nights. There were no significant predictors of uterine rupture.
The rate of survival to hospital discharge was high for bitches with pyometra treated with OHE in a nonspecialized setting; therefore, general practitioners could expect similar outcomes. With this important procedure widely available in general practices, more pets can receive treatment for this life-threatening disease.
Objective—To determine whether particular vaccine
brands, other injectable medications, customary vaccination
practices, or various host factors were associated
with the formation of vaccine-associated sarcomas
Animals—Cats in the United States and Canada with
soft tissue sarcomas or basal cell tumors.
Procedure—Veterinarians submitting biopsy specimens
from cats with a confirmed diagnosis of soft tissue
sarcoma or basal cell tumor were contacted for
patient medical history. Time window statistical analyses
were used in conjunction with various assumptions
about case definitions.
Results—No single vaccine brand or manufacturer
within antigen class was found to be associated with
sarcoma formation. Factors related to vaccine administration
were also not associated with sarcoma
development, with the possible exception of vaccine
temperature prior to injection. Two injectable medications
(long-acting penicillin and methyl prednisolone
acetate) were administered to case cats more frequently
than to control cats.
Conclusions and Clinical Relevance—Findings do
not support the hypotheses that specific brands or
types of vaccine within antigen class, vaccine
practices such as reuse of syringes, concomitant
viral infection, history of trauma, or residence
either increase or decrease the risk of vaccineassociated
sarcoma formation in cats. There was
evidence to suggest that certain long-acting
injectable medications may also be associated
with sarcoma formation. (J Am Vet Med Assoc 2003;223:1283–1292)