• 1.

    Runge JJ, Berent AC, Mayhew PD, Weisse C. Transvesicular percutaneous cystolithotomy for the retrieval of cystic and urethral calculi in dogs and cats: 27 cases (2006–2008). J Am Vet Med Assoc. 2011;239(3):344349. doi:10.2460/javma.239.3.344

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2.

    Lulich JP, Berent AC, Adams LG, Westropp JL, Bartges JW, Osborne CA. ACVIM small animal consensus recommendations on the treatment and prevention of uroliths in dogs and cats. J Vet Intern Med. 2016;30(5):15641574. doi:10.1111/jvim.14559

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3.

    Arulpragasam SP, Case JB, Ellison GW. Evaluation of costs and time required for laparoscopic-assisted versus open cystotomy for urinary cystolith removal in dogs: 43 cases (2009–2012). J Am Vet Med Assoc. 2013;243(5):703708. doi:10.2460/javma.243.5.703

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 4.

    Appel S, Otto SJ, Weese JS. Cystotomy practices and complications among general small animal practitioners in Ontario, Canada. Can Vet J. 2012;53(3):303310.

    • Search Google Scholar
    • Export Citation
  • 5.

    Thieman-Mankin KM, Ellison GW, Jeyapaul CJ, Glotfelty-Ortiz CS. Comparison of short-term complication rates between dogs and cats undergoing appositional single-layer or inverting double-layer cystotomy closure: 144 cases (1993–2010). J Am Vet Med Assoc. 2012;240(1):6568. doi:10.2460/javma.240.1.65

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 6.

    Grant DC, Harper TA, Werre SR. Frequency of incomplete urolith removal, complications, and diagnostic imaging following cystotomy for removal of uroliths from the lower urinary tract in dogs: 128 cases (1994–2006). J Am Vet Med Assoc. 2010;236(7):763766. doi:10.2460/javma.236.7.763

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7.

    Harriman GM, Popovitch C, MacLeod A. Ultrasound evaluation of the urinary bladder in dogs following cystotomy with full thickness suture placement. J Am Anim Hosp Assoc. 2016;52(4):212219. doi:10.5326/JAAHA-MS-6381

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8.

    Mariano AD, Penninck DG, Sutherland-Smith J, Kudej RK. Ultrasonographic evaluation of the canine urinary bladder following cystotomy for treatment of urolithiasis. J Am Vet Med Assoc. 2018;252(9):10901096. doi:10.2460/javma.252.9.1090

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Desch SP, Wagner SD. Urinary bladder incisions in dogs comparison of ventral and dorsal. Vet Surg. 1986;15(2):153155. doi:10.1111/j.1532–950x.1986.tb00195.x

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Martinez I, Mattoon JS, Eaton KA, Chew DJ, DiBartola SP. Polypoid cystitis in 17 dogs (1978–2001). J Vet Intern Med. 2003;17(4):499509. doi:10.1111/j.1939-1676.2003.tb02471.x

    • Search Google Scholar
    • Export Citation
  • 11.

    Papatsoris AG, Varkarakis I, Dellis A, Deliveliotis C. Bladder lithiasis: from open surgery to lithotripsy. Urol Res. 2006;34(3):163167. doi:10.1007/s00240-006-0045-5

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 12.

    Salah MA, Holman E, Khan AM, Toth C. Percutaneous cystolithotomy for pediatric endemic bladder stone: experience with 155 cases from 2 developing countries. J Pediatr Surg. 2005;40(10):16281631. doi:10.1016/j.jpedsurg.2005.06.039

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 13.

    Mahran MR, Dawaba MS. Cystolitholapaxy versus cystolithotomy in children. J Endourol. 2000;14(5):423426. doi:10.1089/end.2000.14.423

  • 14.

    Al-Marhoon MS, Sarhan OM, Awad BA, Helmy T, Ghali A, Dawaba MS. Comparison of endourological and open cystolithotomy in the management of bladder stones in children. J Urol. 2009;181(6):26842687. doi:10.1016/j.juro.2009.02.040

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 15.

    Teichman JM, Rogenes VJ, McIver BJ, Harris JM. Holmium:yttrium-aluminum-garnet laser cystolithotripsy of large bladder calculi. Urology. 1997;50(1):4448. doi:10.1016/S0090-4295(97)00201-X

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 16.

    Grasso M. Experience with the holmium laser as an endoscopic lithotrite. Urology. 1996;48(2):199206. doi:10.1016/S0090-4295(96)00158–6

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 17.

    Drach GW. Calculi of the prostate and seminal vesicles in urinary lithiasis: etiology, diagnosis, and medical management. In: Walsh PC, Retick AB, Stamey TA, Vaughan ED Jr, eds. Campbell’s Urology. 6th ed. Vol 3. WB Saunders; 1992:21422144.

    • Search Google Scholar
    • Export Citation
  • 18.

    Rasmussen F. Healing of urinary bladder wounds. Morphologic and biochemical studies. Proc Soc Exp Biol Med. 1966;123(2):470475. doi:10.3181/00379727-123-31517

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 19.

    Fry CH, Kitney DG, Paniker J, Drake MJ, Kanai A, Andersson K-E. Fibrosis and the bladder, implications for function ICI-RS 2017. Neurourol Urodyn. 2018;37(suppl 4):S7S12. doi:10.1002/nau.23725

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 20.

    Holtz G. Adhesion induction by suture of varying tissue reactivity and caliber. Int J Fertil. 1982;27(3):134135.

  • 21.

    Michel F, Ponsot Y, Roland J, Thibault P, Rouquette AM, Gattegno B. Biological tolerance to polydioxanone absorbable clips: a comparison with metallic ligating clips. Eur Surg Res. 1985;17(6):383387. doi:10.1159/000128495

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 22.

    Neff MR, Holtz GL, Betsill WL Jr. Adhesion formation and histologic reaction with polydioxanone and polyglactin suture. Am J Obstet Gynecol. 1985;151(1):2023. doi:10.1016/0002-9378(85)90416-8

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 23.

    Ellis H. The aetiology of post-operative abdominal adhesions. An experimental study. Br J Surg. 1962;50:1016. doi:10.1002/bjs.18005021904

  • 24.

    Menzies D. Postoperative adhesions: their treatment and relevance in clinical practice. Ann R Coll Surg Engl. 1993;75(3):147153.

  • 25.

    Fossum TW. Chapter 8. Biomaterials, suturing, and hemostasis. Chapter 26. Surgery of the bladder and urethra. In: Small Animal Surgery Textbook. Elsevier Health Sciences; 2013:6466.

    • Search Google Scholar
    • Export Citation
  • 26.

    Pal KM. Urinary bladder wall repair: what suture to use? Br J Urol. 1998;82(2):196198. doi:10.1046/j.1464-410x.1998.00722.x

  • 27.

    Hastings JC, Van Winkle W, Barker E, Hines D, Nichols W. The effect of suture materials on healing wounds of the bladder. Surg Gynecol Obstet. 1975;140(6):933937.

    • Search Google Scholar
    • Export Citation
  • 28.

    McLoughlin MA. Complications of lower urinary tract surgery in small animals. Vet Clin North Am Small Anim Pract. 2011;41(5):889913, v. doi: 10.1016/j.cvsm.2011.07.001

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 29.

    Degner DA, Walshaw R. Healing responses of the lower urinary tract. Vet Clin North Am Small Anim Pract. 1996;26(2):197206.

  • 30.

    Case GD, Glenn JF, Postlethwait RW. Comparison of absorbable sutures in urinary bladder. Urology. 1976;7(2):165168. doi:10.1016/0090-4295(76)90304-6

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 31.

    Greenberg CB, Davidson EB, Bellmer DD, Morton RJ, Payton ME. Evaluation of the tensile strengths of four monofilament absorbable suture materials after immersion in canine urine with or without bacteria (Erratum published in Am J Vet Res. 2004;65[7]:1020). Am J Vet Res. 2004;65(6):847853. doi:10.2460/ajvr.2004.65.847

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 32.

    Schiller TD, Stone EA, Gupta BS. In vitro loss of tensile strength and elasticity of five absorbable suture materials in sterile and infected canine urine. Vet Surg. 1993;22(3):208212. doi:10.1111/j.1532-950x.1993.tb00383.x

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 33.

    Hickey JM, Berent AC, Fischetti AJ, Le Roux AB. Radiographic features of suspected suture-associated cystic calculi in dogs. Vet Radiol Ultrasound. 2020;61(4):394398. doi:10.1111/vru.12863

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 34.

    Appel SL, Lefebvre SL, Houston DM, et al. Evaluation of risk factors associated with suture-nidus cystoliths in dogs and cats: 176 cases (1999–2006). J Am Vet Med Assoc. 2008;233(12):18891895. doi:10.2460/javma.233.12.1889

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 35.

    Le Boedec K, Pastor ML, Lavoué R, Reynolds BS. Pseudomembranous cystitis, an unusual condition associated with feline urine outflow obstruction: four cases. J Feline Med Surg. 2011;13(8):588593. doi:10.1016/j.jfms.2011.02.004

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 36.

    Ruiz-Drebing M, Yap F, Seth M, Dennis R, Dominguez E. Membrane-like structure in the urinary bladder neck of a young cat: diagnosis and treatment using balloon dilatation and a balloon-expandable metallic stent. JFMS Open Rep. 2017;3(2):2055116917733641. doi:10.1177/2055116917733641

    • Search Google Scholar
    • Export Citation
  • 37.

    Barrett JC. Gangrenous. Br J Urol. 1962;34(3):312317. doi:10.1111/j.1464-410x.1962.tb09462.x

  • 38.

    Love A, Notley RG. Vesical necrosis. J R Soc Med. 1978;71(12):895898. doi:10.1177/014107687807101209

  • 39.

    Damjanov I. The lower urinary tract and male reproductive system. In: Rubin R, Strayer DS, eds. Rubin’s Pathology Clinicopathologic Foundations of Medicine. 5th ed. Lippincott Williams & Wilkins; 2008:745780.

    • Search Google Scholar
    • Export Citation
  • 40.

    Zabihi N, Allee T, Maher MG, et al. Bladder necrosis following hydrodistention in patients with interstitial cystitis. J Urol. 2007;177(1):149152. doi:10.1016/j.juro.2006.08.095

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 41.

    Grossklaus DJ, Franke JJ. Vesical necrosis after hydrodistension of the urinary bladder in a patient with interstitial cystitis. BJU Int. 2000;86(1):140141. doi:10.1046/j.1464-410x.2000.01739.x

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 42.

    Himelman JF, Berent AC, Weisse CW, Bagley DH. Use of cystoscopy or cystourethroscopy in treating benign macroscopic hematuria caused by lower urinary tract hemorrhage in three dogs. J Am Vet Med Assoc. 2019;255(1):9097. doi:10.2460/javma.255.1.90

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 43.

    Berent AC, Weisse C, Mayhew PD, Todd K, Wright M, Bagley D. Evaluation of cystoscopic-guided laser ablation of intramural ectopic ureters in female dogs. J Am Vet Med Assoc. 2012;240(6):716725. doi:10.2460/javma.240.6.716

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 44.

    Burdick S, Berent AC, Weisse C, Langston C. Endoscopic-guided laser ablation of vestibulovaginal septal remnants in dogs: 36 cases (2007–2011). J Am Vet Med Assoc. 2014;244(8):944949. doi:10.2460/javma.244.8.944

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 45.

    Rogatko CP, Berent AC, Adams LG, Weisse CW, Bagley D. Endoscopic laser-ablation for the treatment of orthotopic and ectopic ureteroceles in dogs: 13 cases (2008–2017). J Vet Intern Med. 2019;33(2):670679. doi:10.1111/jvim.15424

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 46.

    Kuntz RM. Current role of lasers in the treatment of benign prostatic hyperplasia (BPH). Eur Urol. 2006;49(6):961969. doi:10.1016/j.eururo.2006.03.028

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 47.

    Zarrabi A, Gross AJ. The evolution of lasers in urology. Ther Adv Urol. 2011;3(2):8189. doi:10.1177/1756287211400494

  • 48.

    Bevan JM, Lulich JP, Albasan H, Osborne CA. Comparison of laser lithotripsy and cystotomy for the management of dogs with urolithiasis. J Am Vet Med Assoc. 2009;234(10):12861294. doi:10.2460/javma.234.10.1286

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 49.

    Buote NJ, Kovak-McClaran JR, Loar AS, Cherrone KL. The effect of preoperative antimicrobial administration on culture results in dogs undergoing cystotomy. J Am Vet Med Assoc. 2012;241(9):11851189. doi:10.2460/javma.241.9.1185

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 50.

    Weese JS, Blondeau JM, Boothe D, et al. Antimicrobial use guidelines for treatment of urinary tract disease in dogs and cats: antimicrobial guidelines working group of the International Society for Companion Animal Infectious Diseases. Vet Med Int. 2011;2011:263768. doi:10.4061/2011/263768

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 51.

    Weese JS, Blondeau J, Boothe D, et al. International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J. 2019;247:825. doi:10.1016/j.tvjl.2019.02.008

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 52.

    Papich MG. Saunders Handbook of Veterinary Drugs: Small and Large Animal. Elsevier/Saunders; 2016:592.

  • 53.

    Davila GW, Daugherty CA, Sanders SW; Transdermal Oxybutynin Study Group. A short-term, multicenter, randomized double-blind dose titration study of the efficacy and anticholinergic side effects of transdermal compared to immediate release oral oxybutynin treatment of patients with urge urinary incontinence. J Urol. 2001;166(1):140145.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 54.

    Kennelly MJ. A comparative review of oxybutynin chloride formulations: pharmacokinetics and therapeutic efficacy in overactive bladder. Rev Urol. 2010;12(1):129.

    • Search Google Scholar
    • Export Citation
  • 55.

    Homma Y, Paick JS, Lee JG, Kawabe K; Japanese and Korean Tolterodine Study Group. Clinical efficacy and tolerability of extended-release tolterodine and immediate-release oxybutynin in Japanese and Korean patients with an overactive bladder: a randomized, placebo-controlled trial (Erratum published in BJU Int. 2004;93[7]:1135). BJU Int. 2003;92(7):741747. doi:10.1046/j.1464-410x.2003.04468.x

    • Crossref
    • Search Google Scholar
    • Export Citation

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Bladder wall adhesion causing a vesicular septum in a dog following surgical cystotomy

Lauren J. LewInterventional Radiology and Interventional Endoscopy Service, The Animal Medical Center, New York, NY

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Allyson C. BerentInterventional Radiology and Interventional Endoscopy Service, The Animal Medical Center, New York, NY

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Meghan S. KirschInterventional Radiology and Interventional Endoscopy Service, The Animal Medical Center, New York, NY

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Chick W. WeisseInterventional Radiology and Interventional Endoscopy Service, The Animal Medical Center, New York, NY

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Abstract

CASE DESCRIPTION

An 8-year-old spayed female Yorkshire Terrier–Poodle dog was evaluated for persistent pollakiuria and stranguria following routine cystotomy for calcium oxalate cystoliths.

CLINICAL FINDINGS

The dog presented for a cystotomy with intermittent hematuria. Postoperative radiographs revealed no remaining cystoliths. Urine, cystolith, and bladder mucosal aerobic cultures were negative. Pollakiuria, stranguria, and hematuria developed immediately after surgery and persisted despite antibiotics. Ultrasound revealed suspected fibrous adhesions within the urinary bladder lumen connecting the dorsal and ventral bladder wall creating a septum. This was confirmed cystoscopically 4 weeks after surgery.

TREATMENT AND OUTCOME

Cystoscopic-guided laser ablation was performed to incise abnormal tissue connecting the ventral and dorsal bladder wall using a holmium:yttrium-aluminum-garnet laser. Three weeks later, ultrasound revealed adhesion resolution though mild pollakiuria and stranguria persisted. Oxybutynin was prescribed and clinical signs resolved. At 27 months after ablation, hematuria occurred with recurrent cystoliths. These cystoliths were removed by percutaneous cystolithotomy, documenting a cystoscopically normal bladder wall. The patient had normal urination for 55.5 months after ablation, with normal bladder wall thickness on ultrasound repeated at 27 and 36 months after ablation.

CLINICAL RELEVANCE

To the authors’ knowledge, an adhesion creating a septum between the dorsal and ventral bladder wall has not been previously reported as a complication after cystotomy in any species and should be considered as a cause of persistent lower urinary signs after surgery. Ultrasound identified the lesion in this dog. Because bladder abnormalities can develop quickly after surgery, ultrasound might be considered if urine testing is not supportive of infection. Cystoscopic-guided laser ablation was a successful minimally invasive treatment in this case.

Abstract

CASE DESCRIPTION

An 8-year-old spayed female Yorkshire Terrier–Poodle dog was evaluated for persistent pollakiuria and stranguria following routine cystotomy for calcium oxalate cystoliths.

CLINICAL FINDINGS

The dog presented for a cystotomy with intermittent hematuria. Postoperative radiographs revealed no remaining cystoliths. Urine, cystolith, and bladder mucosal aerobic cultures were negative. Pollakiuria, stranguria, and hematuria developed immediately after surgery and persisted despite antibiotics. Ultrasound revealed suspected fibrous adhesions within the urinary bladder lumen connecting the dorsal and ventral bladder wall creating a septum. This was confirmed cystoscopically 4 weeks after surgery.

TREATMENT AND OUTCOME

Cystoscopic-guided laser ablation was performed to incise abnormal tissue connecting the ventral and dorsal bladder wall using a holmium:yttrium-aluminum-garnet laser. Three weeks later, ultrasound revealed adhesion resolution though mild pollakiuria and stranguria persisted. Oxybutynin was prescribed and clinical signs resolved. At 27 months after ablation, hematuria occurred with recurrent cystoliths. These cystoliths were removed by percutaneous cystolithotomy, documenting a cystoscopically normal bladder wall. The patient had normal urination for 55.5 months after ablation, with normal bladder wall thickness on ultrasound repeated at 27 and 36 months after ablation.

CLINICAL RELEVANCE

To the authors’ knowledge, an adhesion creating a septum between the dorsal and ventral bladder wall has not been previously reported as a complication after cystotomy in any species and should be considered as a cause of persistent lower urinary signs after surgery. Ultrasound identified the lesion in this dog. Because bladder abnormalities can develop quickly after surgery, ultrasound might be considered if urine testing is not supportive of infection. Cystoscopic-guided laser ablation was a successful minimally invasive treatment in this case.

Contributor Notes

Corresponding author: Dr. Berent (Allyson.Berent@amcny.org)