Cover Journal of the American Veterinary Medical Association
Journal of the American Veterinary Medical Association
ISSN:
0003-1488
Publication Date:
15 Feb 2022
  • 1.

    Zingel MM, Sakals SA. Use of skin stretching techniques before bilateral caudal superficial epigastric axial flaps in a dog with severe burns. Can Vet J. 2017;58(8):835–838.

    • Search Google Scholar
    • Export Citation
  • 2.

    Stanley BJ, Pitt KA, Weder CD, Fritz MC, Hauptman JG, Steficek BA. Effects of negative pressure wound therapy on healing of free full-thickness skin grafts in dogs. Vet Surg. 2013;42(5):511–522.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3.

    Mullally C, Carey K, Seshadri R. Case report: use of a nanocrystalline silver dressing and vacuum-assisted closure in a severely burned dog. J Vet Emerg Crit Care (San Antonio). 2010;20(4):456–463.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 4.

    Leung LTF, Papp A. Accelerant-related burns and drug abuse: challenging combination. Burns. 2018;44(3):646–650.

  • 5.

    Jin R, Wu P, Ho JK, Wang X, Han C. Five-year epidemiology of liquefied petroleum gas-related burns. Burns. 2018;44(1):210–217.

  • 6.

    Vaughn L, Beckel N. Severe burn injury, burn shock, and smoke inhalation injury in small animals. Part 1: burn classification and pathophysiology. J Vet Emerg Crit Care (San Antonio). 2012;22(2):179–186.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7.

    Thom D. Appraising current methods for preclinical calculation of burn size – a pre-hospital perspective. Burns. 2017;43(1):127–136.

  • 8.

    Sherman RA. Mechanisms of maggot-induced wound healing: what do we know, and where do we go from here? Evid Based Complement Alternat Med. 2014;(2):592419.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Choudhary V, Choudhary M, Pandey S, Chauhan VD, Hasnani JJ. Maggot debridement therapy as primary tool to treat chronic wound of animals. Vet World. 2016;9(4):403–409.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Sherman RA, Stevens H, Ng D, Iversen E. Treating wounds in small animals with maggot debridement therapy: a survey of practitioners. Vet J. 2007;173(1):138–143.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 11.

    Paul AG, Ahmad NW, Lee HL, et al. Maggot debridement therapy with Lucilia cuprina: a comparison with conventional debridement in diabetic foot ulcers. Int Wound J. 2009;6(1):39–46.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 12.

    Jones G, Wall R. Maggot-therapy in veterinary medicine. Res Vet Sci. 2008;85(2):394–398.

  • 13.

    Steenvoorde P, Budding T, Oskam J. Determining pain levels in patients treated with maggot debridement therapy. J Wound Care. 2005;14(10):485–488.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 14.

    Lang TC, Zhao R, Kim A, et al. A critical update of the assessment and acute management of patients with severe burns. Adv Wound Care (New Rochelle). 2019;8(12):607–633.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 15.

    Davidson JR. Current concepts in wound management and wound healing products. Vet Clin North Am Small Anim Pract. 2015;45(3):537–564.

  • 16.

    Hosgood G. Open wound. In: Johnston S, Tobias K, eds. Veterinary Surgery Small Animal. 2nd ed. Elsevier; 2018:1410–1421.

  • 17.

    Nielson CB, Duethman NC, Howard JM, Moncure M, Wood JG. Burns: pathophysiology of systemic complications and current management. J Burn Care Res. 2017;38(1):e469–e481.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 18.

    Vaughn L, Beckel N, Walters P. Severe burn injury, burn shock, and smoke inhalation injury in small animals. Part 2: diagnosis, therapy, complications, and prognosis. J Vet Emerg Crit Care (San Antonio). 2012;22(2):187–200.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 19.

    Park HS, Pham C, Paul E, Padiglione A, Lo C, Cleland H. Early pathogenic colonisers of acute burn wounds: a retrospective review. Burns. 2017;43(8):1757–1765.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 20.

    Mankin KT. Axial pattern flaps. Vet Clin North Am Small Anim Pract. 2017;47(6):1237–1247.

  • 21.

    Alper RL, Smeak DD. Clinical evaluation of caudal superficial epigastric axial pattern flap reconstruction of skin defects in 10 dogs (1989–2000). J Am Anim Hosp Assoc. 2005;41(3):185–192.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 22.

    Sobczak N, Kantyka M. Hirudotherapy in veterinary medicine. Ann Parasitol. 2014;60(2):89–92.

  • 23.

    Bohling MW, Swaim SF. Skin grafts. In: Johnston S, Tobias K, eds. Veterinary Surgery Small Animal. 2nd ed. Elsevier; 2018:1473–1494.

  • 24.

    Jensen EC. Canine autogenous skin grafting. Am J Vet Res. 1959;20:898–908.

  • 25.

    Scharf VF. Free grafts and microvascular anastomoses. Vet Clin North Am Small Anim Pract. 2017;47(6):1249–1262.

  • 26.

    Skinner OT, Cuddy LC, Coisman JG, Covey JL, Ellison GW. Temporary rectal stenting for management of severe perineal wounds in two dogs. J Am Anim Hosp Assoc. 2016;52(6):385–391.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 27.

    Hughes OB, Rakosi A, Macquhae F, Herskovitz I, Fox JD, Kirsner RS. A review of cellular and acellular matrix products: indications, techniques, and outcomes. Plast Reconstr Surg. 2016;138(3 suppl):138S–147S.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 28.

    Magnússon S, Baldursson BT, Kjartansson H, et al. Decellularized fish skin: characteristics that support tissue repair. Article in Icelandic. Laeknabladid. 2015;101(12):567–573.

    • Search Google Scholar
    • Export Citation
  • 29.

    Michael S, Winters C, Khan M. Acellular fish skin graft use for diabetic lower extremity wound healing: a retrospective study of 58 ulcerations and a literature review. Wounds. 2019;31(10):262–268.

    • Search Google Scholar
    • Export Citation
  • 30.

    Badois N, Bauër P, Cheron M, et al. Acellular fish skin matrix on thin-skin graft donor sites: a preliminary study. J Wound Care. 2019;28(9):624–628.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 31.

    Yang CK, Polanco TO, Lantis JC II. A prospective, postmarket, compassionate clinical evaluation of a novel acellular fish-skin graft which contains omega-3 fatty acids for the closure of hard-to-heal lower extremity chronic ulcers. Wounds. 2016;28(4):112–118.

    • Search Google Scholar
    • Export Citation
  • 32.

    Sandness B, Struble A-M. Use of an acellular fish skin graft rich in omega-3 (Kerecis Omega3 BURN) in a canine burn wound. Michigan State University College of Veterinary Medicine. Accessed July 29, 2019. https://cvm.msu.edu/vetschool-tails/kerecis-graft-canine-burn-wound

    • Search Google Scholar
    • Export Citation
  • 33.

    Sood R, Roggy DE, Zieger MJ, Nazim M, Hartman BC, Gibbs JT. A comparative study of spray keratinocytes and autologous meshed split-thickness skin graft in the treatment of acute burn injuries. Wounds. 2015;27(2):31–40.

    • Search Google Scholar
    • Export Citation
  • 34.

    Esteban-Vives R, Corcos A, Choi MS, et al. Cell-spray auto-grafting technology for deep partial-thickness burns: problems and solutions during clinical implementation. Burns. 2018;44(3):549–559.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 35.

    Vigani A, Culler CA. Systemic and local management of burn wounds. Vet Clin North Am Small Anim Pract. 2017;47(6):1149–1163.

Advertisement

Management of severe burn injuries with novel treatment techniques including maggot debridement and applications of acellular fish skin grafts and autologous skin cell suspension in a dog

Katherine A. Dawson DVM1, Megan A. Mickelson DVM1, April E. Blong DVM1, and Rebecca A. L. Walton DVM1
View More View Less
  • 1 Hixson-Lied Small Animal Hospital, College of Veterinary Medicine, Iowa State University, Ames, IA
DOI:
https://doi.org/10.2460/javma.20.10.0579
Volume/Issue:
Volume 260: Issue 4
Online Publication Date:
26 Nov 2021
Restricted access
Reprints and Permissions Purchase Article

Abstract

CASE DESCRIPTION

A 3-year-old 27-kg female spayed American Bulldog with severe burn injuries caused by a gasoline can explosion was evaluated.

CLINICAL FINDINGS

The dog had extensive partial- and full-thickness burns with 50% of total body surface area affected. The burns involved the dorsum extending from the tail to approximately the 10th thoracic vertebra, left pelvic limb (involving 360° burns from the hip region to the tarsus), inguinal area bilaterally, right medial aspect of the thigh, and entire perineal region. Additional burns affected the margins of the pinnae and periocular regions, with severe corneal involvement bilaterally.

TREATMENT AND OUTCOME

The dog was hospitalized in the hospital’s intensive care unit for 78 days. Case management involved provision of aggressive multimodal analgesia, systemic support, and a combination of novel debridement and reconstructive techniques. Debridement was facilitated by traditional surgical techniques in combination with maggot treatment. Reconstructive surgeries involved 6 staged procedures along with the use of novel treatments including applications of widespread acellular fish (cod) skin graft and autologous skin cell suspension.

CLINICAL RELEVANCE

The outcome for the dog of the present report highlighted the successful use of maggot treatment and applications of acellular cod skin and autologous skin cell suspension along with aggressive systemic management and long-term multimodal analgesia with debridement and wound reconstruction for management of severe burn injuries encompassing 50% of an animal’s total body surface area.

Abstract

CASE DESCRIPTION

A 3-year-old 27-kg female spayed American Bulldog with severe burn injuries caused by a gasoline can explosion was evaluated.

CLINICAL FINDINGS

The dog had extensive partial- and full-thickness burns with 50% of total body surface area affected. The burns involved the dorsum extending from the tail to approximately the 10th thoracic vertebra, left pelvic limb (involving 360° burns from the hip region to the tarsus), inguinal area bilaterally, right medial aspect of the thigh, and entire perineal region. Additional burns affected the margins of the pinnae and periocular regions, with severe corneal involvement bilaterally.

TREATMENT AND OUTCOME

The dog was hospitalized in the hospital’s intensive care unit for 78 days. Case management involved provision of aggressive multimodal analgesia, systemic support, and a combination of novel debridement and reconstructive techniques. Debridement was facilitated by traditional surgical techniques in combination with maggot treatment. Reconstructive surgeries involved 6 staged procedures along with the use of novel treatments including applications of widespread acellular fish (cod) skin graft and autologous skin cell suspension.

CLINICAL RELEVANCE

The outcome for the dog of the present report highlighted the successful use of maggot treatment and applications of acellular cod skin and autologous skin cell suspension along with aggressive systemic management and long-term multimodal analgesia with debridement and wound reconstruction for management of severe burn injuries encompassing 50% of an animal’s total body surface area.

Supplementary Materials

    • Supplementary Figure S1 (PDF 1,439 KB)
    • Supplementary Figure S2 (PDF 1,392 KB)
    • Supplementary Figure S3 (PDF 448 KB)
    • Supplementary Figure S4 (PDF 1,084 KB)
    • Supplementary Figure S5 (PDF 656 KB)
    • Supplementary Figure S6 (PDF 957 KB)
    • Supplementary Figure S7 (PDF 334 KB)

Contributor Notes

Corresponding author: Dr. Walton (rwalton@iastate.edu)