• 1.

    Robat CS, Ammersbach M, Mans C. Avian oncology. Vet Clin North Am Exot Anim Pract. 2017;20(1):5786. doi:10.1016/j.cvex.2016.07.009

  • 2.

    Reavill DR. Tumors of pet birds. Vet Clin North Am Exot Anim Pract. 2004;7(3):537560. doi:10.1016/j.cvex.2004.04.008

  • 3.

    Burgmann PM. Pulmonary fibrosarcoma with hepatic metastases in a cockatiel (Nymphicus hollandicus). J Assoc Avian Med. 1994;8(2):8184. doi:10.2307/27671122

    • Search Google Scholar
    • Export Citation
  • 4.

    Riddell C, Cribb PH. Fibrosarcoma in an African grey parrot (Psittacus erithacus). Avian Dis. 1983;27(2):549555. doi:10.2307/1590185

  • 5.

    Leach M. A survey of neoplasia in pet birds. Semin Avian Exot Pet Med. 1992;1(2):5264.

  • 6.

    Turrel JM, McMillan MC, Paul-Murphy J. Diagnosis and treatment of tumors of companion birds I. AAV Today 1987;1(3):109116. doi:10.2307/27670245

    • Search Google Scholar
    • Export Citation
  • 7.

    Robertson J, Guzman DS, Sinnott D, Woolard K, Nesset A, Paul-Murphy JR. Modified tail amputation technique in a blue and gold macaw (Ara ararauna) with uropygial gland adenocarcinoma. J Avian Med Surg. 2020;34(1):5764. doi:10.1647/1082-6742-34.1.57

    • Search Google Scholar
    • Export Citation
  • 8.

    Montesinos A, Encinas T, Ardiaca M, Gilabert JA, Bonvehí C, Orós J. Pharmacokinetics of meloxicam during multiple oral or intramuscular dose administration to African grey parrots (Psittacus erithacus). Am J Vet Res. 2019;80(2):201207. doi:10.2460/ajvr.80.2.201

    • Search Google Scholar
    • Export Citation
  • 9.

    Montesinos A, Ardiaca M, Gilabert JA, Bonvehí C, Orós J, Encinas T. Pharmacokinetics of meloxicam after intravenous, intramuscular and oral administration of a single dose to African grey parrots (Psittacus erithacus). J Vet Pharmacol Ther. 2017;40(3):279284. doi:10.1111/jvp.12350

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Gruet P, Seewald W, King JN. Evaluation of subcutaneous and oral administration of robenacoxib and meloxicam for the treatment of acute pain and inflammation associated with orthopedic surgery in dogs. Am J Vet Res. 2011;72(2):184193. doi:10.2460/ajvr.72.2.184

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    Offinger J, Herdtweck S, Rizk A, et al. Postoperative analgesic efficacy of meloxicam in lame dairy cows undergoing resection of the distal interphalangeal joint. J Dairy Sci. 2013;96(2):866876. doi:10.3168/jds.2011-4930

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12.

    Ramsay EC, Bos JH, McFadden C. Use of intratumoral cisplatin and orthovoltage radiotherapy in treatment of a fibrosarcoma in a macaw. J Assoc Avian Med. 1993;7(2):8790. doi:10.2307/30135011

    • Search Google Scholar
    • Export Citation
  • 13.

    Lamberski N, Théon AP. Concurrent irradiation and intratumoral chemotherapy with cisplatin for treatment of a fibrosarcoma in a blue and gold macaw (Ara ararauna). J Avian Med Surg. 2002;16(3):234238. doi:10.1647/1082–6742(2002)016[0234:ciaicw]2.0.co;2

    • Search Google Scholar
    • Export Citation
  • 14.

    Mauldin GN, Shiomitsu K. Principles and practice of radiation therapy in exotic and avian species. Semin Avian Exot Pet Med. 2005;14(3):168174. doi:10.1053/j.saep.2005.07.001

    • Search Google Scholar
    • Export Citation
  • 15.

    Barron HW, Roberts RE, Latimer KS, Hernandez-Divers S, Northrup NC. Tolerance doses of cutaneous and mucosal tissues in ring-necked parakeets (Psittacula krameri) for external beam megavoltage radiation. J Avian Med Surg. 2009;23(1):69. doi:10.1647/2008-012R.1

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    Forrest LJ, Chun R, Adams WM, Vail DM. Postoperative radiotherapy for canine soft tissue sarcoma. J Vet Intern Med. 2000;14(6):578582. doi:10.1892/0891-6640(2000)014<0578:prfcst>2.3.co;2

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17.

    Gunkel C, Lafortune M. Current techniques in avian anesthesia. Semin Avian Exot Pet Med. 2005;14(4):263276. doi:10.1053/j.saep.2005.09.006

    • Search Google Scholar
    • Export Citation
  • 18.

    Zehnder A, Graham J, Antonissen G. Update on cancer treatment in exotics. Vet Clin North Am Exot Anim Pract. 2018;21(2):465509. doi:10.1016/j.cvex.2018.01.012

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 19.

    Filippich LJ, Bucher AM, Charles BG. Platinum pharmacokinetics in sulphur-crested cockatoos (Cacatua galerita) following single-dose cisplatin infusion. Aust Vet J. 2000;78(6):406411. doi:10.1111/j.1751-0813.2000.tb11829.x

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20.

    Filippich LJ, Bucher AM, Charles BG, Sutton RH. Intravenous cisplatin administration in sulphur-crested cockatoos (Cacatua galerita): clinical and pathologic observations. J Avian Med Surg. 2001;15(1):2330. doi:10.1647/1082–6742(2001)015[0023:icaisc]2.0.co;2

    • Search Google Scholar
    • Export Citation
  • 21.

    Jaensch SM, Butler R, O’Hara A, Raidal SR, Wyatt K. Atypical multiple, papilliform, xanthomatous, cutaneous neoplasia in a goose (Anser anser). Aust Vet J. 2002;80(5):277280. doi:10.1111/j.1751-0813.2002.tb10838.x

    • Search Google Scholar
    • Export Citation
  • 22.

    Ferrell ST, Marlar AB, Garner M, Lung NP. Intralesional cisplatin chemotherapy and topical cryotherapy for the control of choanal squamous cell carcinoma in an African penguin (Spheniscus demersus). J Zoo Wildl Med. 2006;37(4):539541. doi:10.1638/05-028.1

    • Search Google Scholar
    • Export Citation

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Successful radiation treatment of undertail fibrosarcoma in a Major Mitchell’s cockatoo (Lophochroa leadbeateri)

Daria HinkleDepartment of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS

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David EsharDepartment of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS

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Neta AmbarDepartment of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS

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Sarah SchneiderDepartment of Diagnostic Medicine/Pathology, Kansas State Veterinary Diagnostic Laboratory, Manhattan, KS

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Chieko AzumaDepartment of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS

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Abstract

CASE DESCRIPTION

A male Major Mitchell’s cockatoo (Lophochroa leadbeateri) of unknown age presented with an ulcerated mass on the ventral tail caudodorsal to the cloaca.

CLINICAL FINDINGS

An impression smear of the mass showed spindle cell atypia. Multiple biopsies were submitted for histopathology with inconclusive results. A CT scan revealed a soft tissue mass causing compression of the cloacal lumen. The patient underwent surgical debulking, and a core of the mass was submitted again for histopathology, which reported it as fibrosarcoma.

TREATMENT AND OUTCOME

Under repeated general isoflurane gas anesthesia, the patient received a course of definitive radiation therapy totaling 60 Gy and divided in 3 Gy X 20 fractions. By treatment completion, the lesion had decreased in size with necrotic debris on the surface. Surrounding tissues appeared healthy and no adverse effects were observed. As of 1.5 years post-treatment, the mass appears completely healed with no signs of reoccurrence.

CLINICAL RELEVANCE

This case suggests that radiation therapy with this protocol could be an effective treatment option for fibrosarcoma in avian species.

Abstract

CASE DESCRIPTION

A male Major Mitchell’s cockatoo (Lophochroa leadbeateri) of unknown age presented with an ulcerated mass on the ventral tail caudodorsal to the cloaca.

CLINICAL FINDINGS

An impression smear of the mass showed spindle cell atypia. Multiple biopsies were submitted for histopathology with inconclusive results. A CT scan revealed a soft tissue mass causing compression of the cloacal lumen. The patient underwent surgical debulking, and a core of the mass was submitted again for histopathology, which reported it as fibrosarcoma.

TREATMENT AND OUTCOME

Under repeated general isoflurane gas anesthesia, the patient received a course of definitive radiation therapy totaling 60 Gy and divided in 3 Gy X 20 fractions. By treatment completion, the lesion had decreased in size with necrotic debris on the surface. Surrounding tissues appeared healthy and no adverse effects were observed. As of 1.5 years post-treatment, the mass appears completely healed with no signs of reoccurrence.

CLINICAL RELEVANCE

This case suggests that radiation therapy with this protocol could be an effective treatment option for fibrosarcoma in avian species.

Contributor Notes

Corresponding author: Ms. Hinkle (dhagan7@vet.k-state.edu)