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Pathology in Practice

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  • 1 Idexx Laboratories, One Idexx Drive, Westbrook, ME
  • | 2 Department of Comparative, Diagnostic and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL

An 8-month-old 783-g male castrated domestic ferret (Mustela putorius furo) was evaluated because of a 3-month history of progressive paraparesis, marked neutrophilic leukocytosis (most recent WBC count was 58 × 103 cells/μL) and pyrexia. Prior multi-antimicrobial and anti-inflammatory treatments (including a short course of corticosteroids) had negligible effect. A distemper vaccine (unknown manufacturer) was previously administered at 3 months of age.

Clinical and Clinicopathologic Findings

On physical examination, the ferret was febrile and lethargic, with hind limb paraparesis. Respiratory and heart rates were high. Abdominal palpation revealed marked splenomegaly, which had uniform echotexture on ultrasonographic

Contributor Notes

Corresponding author: Dr. Tomblin (lcharlesdvm@gmail.com)