An approximately 1-year-old 70-kg (154-lb) Lleyn cross ewe was found dead in a lambing pen. Thirteen days earlier, the ewe had given birth to twin lambs unassisted. No other clinical history was available.
The ewe underwent necropsy examination. For histologic analysis, tissue samples from all major organs were fixed in neutral-buffered 10% formalin solution.
Gross examination of the udder revealed that both mammae were diffusely and markedly enlarged, the skin overlying the glands was multifocally dark red to purple with black around the teats, and serosanguineous fluid exuded from the skin and teats. On transverse