ECG of the Month

Kelly E. Wiggen Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.

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Carley Saelinger VCA Animal Specialty and Emergency Center, 1535 S Sepulveda Blvd, Los Angeles, CA 90025.

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Contributor Notes

Address correspondence to Dr. Wiggen (wiggenk@missouri.edu).
  • 1. Kellihan HB, Stepien RL. Pulmonary hypertension in dogs: diagnosis and therapy. Vet Clin North Am Small Anim Pract 2010;40:623–641.

  • 2. Kittleson MD. Diagnosis and treatment of arrhythmias (dysrhythmias). In: Kittleson MD, Kienle RD, eds. Small animal cardiovascular medicine. St Louis: Mosby, 1998;449–494.

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  • 3. Levy MN, Edflstein J. The mechanism of synchronization in isorhythmic AV dissociation. II. Clinical studies. Circulation 1970;42:689–699.

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  • 4. Ettinger S, Buergelt CD. Atrioventricular dissociation (incomplete) with accrochage in a dog with ruptured chordae tendinae. Am J Vet Res 1968;29:1499–1503.

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  • 5. Bright JM, Lombard CW. ECG of the month: atrioventricular junctional tachycardia producing atrioventricular dissociation. J Am Vet Med Assoc 1983;182:580–581.

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  • 6. Perego M, Ramera L, Santilli RA. Isorhythmic atrioventricular dissociation in Labrador Retrievers. J Vet Intern Med 2012;26:320–325.

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  • 7. Maudlin GE, Fox PR, Patnaik AK, et al. Doxorubicin-induced cardiotoxicosis: clinical features in 32 dogs. J Vet Intern Med 1992;6:82–88.

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  • 8. Sisson D, O'Grady MR, Calvert CA. Myocardial diseases of dogs. In: Fox PR, Sisson D, Moise NS, eds. Textbook of canine and feline cardiology. 2nd ed. Philadelphia: WB Saunders Co, 1999;581–619.

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  • 9. Zhang S, Liu X, Bawa-Khalfe T, et al. Identification of the molecular basis of doxorubicin-induced toxicity. Nat Med 2012;18:1639–1642.

  • 10. Page RL, Keene BW. Doxorubicin cardiomyopathy. In: Kirk RW, Bonagura JD, eds. Kirk's current veterinary therapy XI. Philadelphia: WB Saunders Co, 1992;783–785.

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  • 11. Launchbury AP, Habboubi N. Epirubicin and doxorubicin: a comparison of their characteristics, therapeutic activity, and toxicity. Cancer Treat Rev 1993;19:197–228.

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  • 12. Kim SE, Liptak JM, Gall TT, et al. Epirubicin in the adjuvant treatment of splenic hemangiosarcoma in dogs: 59 cases (1997–2004). J Am Vet Med Assoc 2007;231:1550–1557.

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  • 13. Ganzina F. 4′-epi-doxorubicin, a new analogue of doxorubicin: a preliminary overview of preclinical and clinical data. Cancer Treat Rev 1983;10:1–22.

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  • 14. Sobic-Saranovic D, Pavlovic S, Susnjar S, et al. Assessment of early epirubicin cardiotoxicity in women with breast cancer. Anticancer Res 1997;17:3889–3891.

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  • 15. Gennari A, Salvadoria B, Donati S, et al. Cardiotoxicity of epirubicin/paclitaxel-containing regimens: role of cardiac risk factors. J Clin Oncol 1999;17:3596–3602.

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  • 16. Feenstra J, Grobbee DE, Remme WJ, et al. Drug-induced heart failure. J Am Coll Cardiol 1999;33:1152–1162.

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