A 3-year-old 40-kg (88-lb) castrated male Doberman Pinscher (resident in New York state) was evaluated on an emergency basis because of respiratory distress. Nine months prior to the evaluation, the dog had been evaluated because of bilateral swollen carpi, and radiography had revealed an aggressive bone lesion (ABL). The condition of the carpi became progressively worse, leading to forelimb lameness; the dog had also developed coughing, sneezing, and epistaxis. Treatment with diphenhydramine (as needed) and amoxicillin (for 30 days) was initiated. Cytologic examination of a fine-needle aspirate specimen from an enlarged popliteal lymph node revealed evidence of histiocytic inflammation.
Ms. Canales was a 4th-year veterinary student at the time of the case workup.