• 1. Atwater SW, Powers BE, Park RD, et al. Thymoma in dogs: 23 cases (1980–1992). J Am Vet Med Assoc 1994; 205: 10071013.

  • 2. Migaki G. Hematopoietic neoplasms of slaughter animals. Natl Cancer Inst Monogr 1969; 32: 121151.

  • 3. Sandison AT, Anderson LJ. Tumors of the thymus in cattle, sheep, and pigs. Cancer Res 1969; 29: 11461150.

  • 4. Verley JM, Hollmann KH. Thymoma: a comparative study of clinical stages, histologic features, and survival in 200 cases. Cancer 1985; 55: 10741086.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5. Okumura M, Miyoshi S, Fujii Y, et al. Clinical and functional significance of WHO classification on human thymic epithelial neoplasms: a study of 146 consecutive tumors. Am J Surg Pathol 2001; 25: 103110.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 6. Zitz JC, Birchard SJ, Couto GC, et al. Results of excision of thymoma in cats and dogs: 20 cases (1984–2005). J Am Vet Med Assoc 2008; 232: 11861192.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7. Robat CS, Cesario L, Gaeta R, et al. Clinical features, treatment options, and outcome in dogs with thymoma: 116 cases (1999–2010). J Am Vet Med Assoc 2013; 243: 14481454.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8. Löhr CV. One hundred two tumors in 100 goats (1987–2011). Vet Pathol 2013; 50: 668675.

  • 9. Hadlow WJ. High prevalence of thymoma in the dairy goat. Report of seventeen cases. Vet Pathol 1978; 15: 153169.

  • 10. Withrow SJ. Miscellaneous tumors: thymoma. In: Withrow SJ, MacEwen EG, eds. Small animal clinical oncology. 2nd ed. Philadelphia: WB Saunders Co, 1996; 530533.

    • Search Google Scholar
    • Export Citation
  • 11. Klebanow ER. Thymoma and acquired myasthenia gravis in the dog: a case report and review of 13 additional cases. J Am Anim Hosp Assoc 1992; 28: 6369.

    • Search Google Scholar
    • Export Citation
  • 12. Rostkowski CM, Stirtzinger T, Baird JD. Congestive heart failure associated with thymoma in two Nubian goats. Can Vet J 1985; 26: 267269.

    • Search Google Scholar
    • Export Citation
  • 13. Olchowy TWJ, Toal RL, Brenneman KA, et al. Metastatic thymoma in a goat. Can Vet J 1996; 37: 165167.

  • 14. Parish SM, Middleton JR, Baldwin TJ. Clinical megaoesophagus in a goat with thymoma. Vet Rec 1996; 139: 94.

  • 15. Smith AN, Wright JC, Brawner WR, et al. Radiation therapy in the treatment of canine and feline thymomas: a retrospective study (1985–1999). J Am Anim Hosp Assoc 2001; 37: 489496.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 16. Wright CD. Management of thymomas. Crit Rev Oncol Hematol 2008; 65: 109120.

  • 17. Wright CD, Kessler KA. Surgical treatment of thymic tumors. Semin Thorac Cardiovasc Surg 2005; 17: 2026.

  • 18. Burk RL, Feeney DA. The thorax. In: Small animal radiology and ultrasonography. 3rd ed. St Louis: Elsevier Science, 2003; 25248.

  • 19. Dyce KM, Sack WO, Wensing CJG. The head and ventral cervical of the ruminants. In: Textbook of veterinary anatomy. 3rd ed. Philadelphia: Elsevier, 2002; 627648.

    • Search Google Scholar
    • Export Citation
  • 20. Dyce KM, Sack WO, Wensing CJG. The thorax of the carnivores. In: Textbook of veterinary anatomy. 3rd ed. Philadelphia: Elsevier, 2002; 403416.

    • Search Google Scholar
    • Export Citation
  • 21. Aronsohn M. Canine thymoma. Vet Clin North Am Small Anim Pract 1985; 15: 755767.

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Clinical features, treatment, and outcome in goats with thymomas: 13 cases (1990–2014)

Jacqueline A. HillDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.

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Susan L. FubiniDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.

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Richard P. HackettDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.

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Abstract

OBJECTIVE To determine the anatomic location and clinical signs of thymoma in goats and long-term outcomes in a subset of goats treated by tumor excision.

DESIGN Retrospective case series.

ANIMALS 13 goats with a histologic diagnosis of thymoma at the Cornell University Hospital for Animals between 1990 and 2014.

PROCEDURES Medical records of goats with thymoma were reviewed and data were evaluated regarding signalment, clinical signs, diagnostic imaging results, thymoma size, treatment, and outcome. Follow-up information was obtained via contact with the owners and review of medical records.

RESULTS 8 goats had a mediastinal mass, 4 had a palpable ventral cervical mass, and 1 had both types of masses. Median age at the time of diagnosis was 9.5 years (range, 3 to 12 years). Goats with a mediastinal mass had respiratory distress or marked tachypnea. Six goats were treated surgically, including all 5 with a ventral cervical mass. All 5 goats with a ventral cervical mass survived with no tumor recurrence for ≥ 1 year after excision. Only 2 goats with a mediastinal mass survived to hospital discharge.

CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that the prognosis for goats following excision of ventral cervical thymomas was favorable, whereas goats with mediastinal thymomas appeared more likely to have severe clinical signs and a guarded prognosis.

Abstract

OBJECTIVE To determine the anatomic location and clinical signs of thymoma in goats and long-term outcomes in a subset of goats treated by tumor excision.

DESIGN Retrospective case series.

ANIMALS 13 goats with a histologic diagnosis of thymoma at the Cornell University Hospital for Animals between 1990 and 2014.

PROCEDURES Medical records of goats with thymoma were reviewed and data were evaluated regarding signalment, clinical signs, diagnostic imaging results, thymoma size, treatment, and outcome. Follow-up information was obtained via contact with the owners and review of medical records.

RESULTS 8 goats had a mediastinal mass, 4 had a palpable ventral cervical mass, and 1 had both types of masses. Median age at the time of diagnosis was 9.5 years (range, 3 to 12 years). Goats with a mediastinal mass had respiratory distress or marked tachypnea. Six goats were treated surgically, including all 5 with a ventral cervical mass. All 5 goats with a ventral cervical mass survived with no tumor recurrence for ≥ 1 year after excision. Only 2 goats with a mediastinal mass survived to hospital discharge.

CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that the prognosis for goats following excision of ventral cervical thymomas was favorable, whereas goats with mediastinal thymomas appeared more likely to have severe clinical signs and a guarded prognosis.

Contributor Notes

Address correspondence to Dr. Hackett (rph2@cornell.edu).