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1. American Heartworm Society. Current feline guidelines for the prevention, diagnosis, and management of heartworm (Dirofilaria immitis) infection in cats. Wilmington, Del: American Heartworm Society, 2014;1–12.
-
2. Ryan WG, Newcomb KM. Prevalence of feline heartworm disease: a global review, in Proceedings. Heartworm Symp ′95 1995;79–85.
-
3. Guerrero J, McCall JW, Dzimianski MT, et al. Prevalence of Dirofilaria immitis infection in cats from the southeastern United States, in Proceedings. Heartworm Symp ′92 1992;91–96.
-
4. Venco L, Genchi M, Genchi C, et al. Can heartworm prevalence in dogs be used as provisional data for assessing the prevalence of the infection in cats? Vet Parasitol 2011; 176: 300–303.
-
5. Levy JK, Snyder PS, Taveres LM, et al. Prevalence and risk factors for heartworm infection in cats from northern Florida. J Am Anim Hosp Assoc 2003; 39: 533–537.
-
6. Willard MD, Roberts RE, Allison N, et al. Diagnosis of Aelurostrongylus abstrusus and Dirofilaria immitis infections in cats from a humane shelter. J Am Vet Med Assoc 1988; 192: 913–916.
-
7. Courtney CH, Zeng QY. The structure of heartworm populations in dogs and cats of Florida, in Proceedings. Heartworm Symp ′89 1989;1–6.
-
8. Carleton RE, Tolbert MK. Prevalence of Dirofilaria immitis and gastrointestinal helminths in cats euthanized at animal control agencies in northwest Georgia. Vet Parasitol 2004; 119: 319–326.
-
9. Patton S, McCracken MD. Prevalence of Dirofilaria immitis in cats and dogs in eastern Tennessee. J Vet Diagn Invest 1991; 3: 79–80.
-
10. Elkins AD, Kadel W. Feline heartworm disease and its incidence in western Kentucky. Compend Contin Educ Pract Vet 1998; 10: 585–589.
-
11. Levy JK, Crawford PC, Hartmann K, et al. 2008 American Association of Feline Practitioners' feline retrovirus management guidelines. J Feline Med Surg 2008;10:300–316.
-
12. Nelson CTMJ, Carithers D. Current canine guidelines for the prevention, diagnosis, and management of heartworm (Dirofilaria immitis) infection in dogs. Wilmington, Del: American Heartworm Society, 2014;1–22.
-
13. Lorentzen L, Caola AE. Incidence of positive heartworm antibody and antigen tests at IDEXX Laboratories: trends and potential impact on feline heartworm awareness and prevention. Vet Parasitol 2008; 158: 183–190.
-
14. Fox JC, Wagner R, Crotty C. Development of a PCR test and IFA test for Dirofilaria immitis in cats and their use along with ELISA heartworm antigen test to determine the prevalence of infections in the Tulsa, Oklahoma area, in Proceedings. Heartworm Symp ′98 1998;167–171.
-
15. Robertson-Plouch CK, Dillon AR, Brawner WR, et al. Prevalence of feline heartworm infections among cats with respiratory and gastrointestinal signs: results of a multicenter study. Vet Ther 2000; 1: 88–95.
-
16. Miller MW, Atkins CE, Stemme K, et al. Prevalence of exposure to Dirofilaria immitis in cats in multiple areas of the United States. Vet Ther 2000; 1: 169–175.
-
17. Harpster NK, Zook BC. The cardiovascular system. In: Holzworth J, ed. Diseases of the cat: medicine and surgery. Philadelphia: WB Saunders, 1987;905.
-
18. Knight DH, Atkins CE, Atwell RB, et al. 1999 guidelines for the diagnosis, treatment, and prevention of heartworm (Dirofilaria immitis) infection in cats. Vet Ther 2001;2: 78–87.
-
19. Mansour AE, McCall JW, McTier TL, et al. Epidemiology of feline dirofilariasis—infections induced by simulated natural exposure to Aedes aegypti experimentally infected with heartworms, in Proceedings. Heartworm Symp ′95 1995;87–95.
-
20. McTier TL, McCall JW, Dzimianski MT, et al. Prevention of heartworm infection in cats by treatment with ivermectin at one month post-infection, in Proceedings. Heartworm Symp ′92 1992;111–116.
-
21. Companion Animal Parasite Council. Feline heartworm. Available at: www.capcvet.org/capc-recommendations/feline-heartworm. Accessed Oct 27, 2015.
-
22. Dunn KF, Levy JK, Colby KN, et al. Diagnostic, treatment, and prevention protocols for feline heartworm infection in animal shelters. Vet Parasitol 2011; 176: 342–429.
-
23. Brakke Consulting. 2014 US flea control & heartworm markets. Dallas: Brakke Consulting, 2014.
-
24. Volk JO, Felsted KE, Thomas JG, et al. Executive summary of the Bayer veterinary care usage study. J Am Vet Med Assoc 2011; 238: 1275–1282.
-
25. Velasquez L, Blagburn BL, Duncan-Decoq R, et al. Increased prevalence of Dirofilaria immitis antigen in canine samples after heat treatment. Vet Parasitol 2014; 206: 67–70.
-
26. Little SE, Raymond MR, Thomas JE, et al. Heat treatment prior to testing allows detection of antigen of Dirofilaria immitis in feline serum. Parasit Vectors 2014; 13: 1–4.
-
27. Gruntmeir JM, Adolph CB, Thomas JE, et al. Increased detection of Dirofilaria immitis antigen in cats after heat pretreatment of samples [published online ahead of print Sep 30, 2016]. J Feline Med Surg doi:10.1177/1098612X16670562.
-
28. Berdoulay P, Levy JK, Snyder PS, et al. Comparison of serological tests for the detection of natural heartworm infection in cats. J Am Anim Hosp Assoc 2004; 40: 376–384.
-
29. Snyder PS, Levy JK, Salute ME, et al. Performance of serologic tests used to detect heartworm infection in cats. J Am Vet Med Assoc 2000; 216: 693–700.
-
30. Dillon AR, Brawner AR Jr, Robertson-Plouch CK, et al. Feline heartworm disease: correlations of clinical signs, serology, and other diagnostics—results of a multicenter study. Vet Ther 2000; 1: 176–182.
-
31. Atkins CE, DeFrancesco TC, Miller MW, et al. Prevalence of heartworm infection in cats with signs of cardiorespiratory abnormalities. J Am Vet Med Assoc 1998; 212: 517–520.
-
32. American Pet Products Association. 2015–2016 APPA national pet owners survey. Available at: www.americanpetproducts.org/press_industrytrends.asp. Accessed Oct 27, 2015.
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Seroprevalence of heartworm infection, risk factors for seropositivity, and frequency of prescribing heartworm preventives for cats in the United States and Canada
Abstract
OBJECTIVE To determine the seroprevalence of heartworm infection, risk factors for seropositivity, and frequency of prescribing heartworm preventives for cats.
DESIGN Prospective cross-sectional study.
ANIMALS 34,975 cats from 1,353 veterinary clinics (n = 26,707) and 125 animal shelters (8,268) in the United States and Canada.
PROCEDURES Blood samples were collected from all cats and tested with a point-of-care ELISA for Dirofilaria immitis antigen, FeLV antigen, and FIV antibody. Results were compared among geographic regions and various cat groupings.
RESULTS Seropositivity for heartworm antigen in cats was identified in 35 states but not in Canada; overall seroprevalence in the United States was 0.4%. Seroprevalence of heartworm infection was highest in the southern United States. A 3-fold increase in the proportion of seropositive cats was identified for those with (vs without) outdoor access, and a 2.5-fold increase was identified for cats that were unhealthy (vs healthy) when tested. Seroprevalence was 0.3% in healthy cats, 0.7% in cats with oral disease, 0.9% in cats with abscesses or bite wounds, and 1.0% in cats with respiratory disease. Coinfection with a retrovirus increased the risk of heartworm infection. Heartworm preventives were prescribed for only 12.6% of cats at testing, and prescribing was more common in regions with a higher seroprevalence.
CONCLUSIONS AND CLINICAL RELEVANCE At an estimated prevalence of 0.4%, hundreds of thousands of cats in the United States are likely infected with heartworms. Given the difficulty in diagnosing infection at all clinically relevant parasite stages and lack of curative treatment options, efforts should be increased to ensure all cats receive heartworm preventives.
Contributor Notes
Dr. Burling's present address is College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.
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