A 10-week-old 1.6-kg (3.5-lb) sexually intact male mixed-breed dog was evaluated because of progressive nasal discharge and chemosis, sudden onset of seizures, respiratory distress, and lethargy. The puppy had been purchased from a local pet store 1 week prior.
On physical examination, the puppy was dull and unresponsive, tachycardic, and tachypneic. The puppy was 7% to 10% dehydrated and had pale mucous membranes, severe chemosis with marked scleral injection, and diffuse corneal edema in both eyes (Figure 1). Harsh bronchovesicular lung sounds were auscultated in all thoracic quadrants. Moderate abdominal distension was present. A full