1. Witsberger TH, Villamil JA, Schultz LG, et al. Prevalence of and risk factors for hip dysplasia and cranial cruciate ligament deficiency in dogs. J Am Vet Med Assoc 2008; 232: 1818–1824.
2. Hayashi K, Frank JD, Dubinsky C, et al. Histologic changes in ruptured canine cranial cruciate ligament. Vet Surg 2003; 32: 269–277.
3. Morris E, Lipowitz AJ. Comparison of tibial plateau angles in dogs with and without cranial cruciate ligament injuries. J Am Vet Med Assoc 2001; 218: 363–366.
4. Wilke VL, Conzemius MG, Besancon MF, et al. Comparison of tibial plateau angle between clinically normal Greyhounds and Labrador Retrievers with and without rupture of the cranial cruciate ligament. J Am Vet Med Assoc 2002; 221: 1426–1429.
5. Reif U, Probst CW. Comparison of tibial plateau angles in normal and cranial cruciate deficient stifles of Labrador Retrievers. Vet Surg 2003; 32: 385–389.
6. Ragetly CA, Evans R, Mostafa AA, et al. Multivariate analysis of morphometric characteristics to evaluate risk factors for cranial cruciate ligament deficiency in Labrador Retrievers. Vet Surg 2011; 40: 327–333.
7. Paley D. Sagittal plane deformities. In: Herzenberg JE, ed. Principles of deformity correction. Berlin: Springer-Verlag, 2002;155–174.
8. Paley D. Malalignment and malorientation in the frontal plane. In: Herzenberg JE, ed. Principles of deformity correction. Berlin: Springer-Verlag, 2002;19–30.
9. Dismukes DI, Tomlinson JL, Fox DB, et al. Radiographic measurement of the proximal and distal mechanical joint angles in the canine tibia. Vet Surg 2007; 36: 699–704.
10. Dismukes DI, Tomlinson JL, Fox DB, et al. Radiographic measurement of canine tibial angles in the sagittal plane. Vet Surg 2008; 37: 300–305.
11. Fox DB, Tomlinson JL. Principles of angular limb deformity correction. In: Tobias KM, Johnston SA, eds. Veterinary surgery: small animal. St Louis: Saunders Elsevier, 2012;657–668.
12. Cabrera SY, Owen TJ, Mueller MG, et al. Comparison of tibial plateau angles in dogs with unilateral versus bilateral cranial cruciate ligament rupture: 150 cases (2000–2006). J Am Vet Med Assoc 2008; 232: 889–892.
13. Buote N, Fusco J, Radasch R. Age, tibial plateau angle, sex, and weight as risk factors for contralateral rupture of the cranial cruciate ligament in Labradors. Vet Surg 2009; 38: 481–489.
14. Doverspike M, Vasseur PB, Harb MF, et al. Contralateral cranial cruciate ligament rupture: incidence in 114 dogs. J Am Anim Hosp Assoc 1993; 29: 167–170.
15. Moore KW, Read RA. Cranial cruciate ligament rupture in the dog—a retrospective study comparing surgical techniques. Aust Vet J 1995; 72: 281–285.
16. de Bruin T, de Rooster H, Bosmans T, et al. Radiographic assessment of the progression of osteoarthrosis in the contralateral stifle joint of dogs with a ruptured cranial cruciate ligament. Vet Rec 2007; 161: 745–750.
17. Grierson J, Asher L, Grainger K. An investigation into risk factors for bilateral canine cruciate ligament rupture. Vet Comp Orthop Traumatol 2011; 24: 192–196.
18. Muir P, Schwartz Z, Malek S, et al. Contralateral cruciate survival in dogs with unilateral non-contact cranial cruciate ligament rupture. PLoS ONE 2011; 6:e25331.
19. Erne JB, Goring RL, Kennedy FA, et al. Prevalence of lymphoplasmacytic synovitis in dogs with naturally occurring cranial cruciate ligament rupture. J Am Vet Med Assoc 2009; 235: 386–390.
20. Bleedorn JA, Greuel EN, Manley PA, et al. Synovitis in dogs with stable stifle joints and incipient cranial cruciate ligament rupture: a cross-sectional study. Vet Surg 2011; 40: 531–543.
21. Jacobson JA, Girish G, Jiang Y, et al. Radiographic evaluation of arthritis: degenerative joint disease and variations. Radiology 2008; 248: 737–747.
22. Widmer WR, Beckwalter KA, Braunstein EM, et al. Radiographic and magnetic resonance imaging of the stifle joint in experimental osteoarthritis of dogs. Vet Radiol Ultrasound 1994; 35: 371–383.
23. Piermattei D, Flo GL, DeCamp C. The stifle joint. In: Fathman L, ed. Brinker, Piermattei and Flo's handbook of small animal orthopedics and fracture repair. 4th ed. St Louis: Saunders-Elsevier, 2006;582–585.
24. Kowaleski MP, Boudrieau RJ, Pozzi A. Stifle joint. In: Tobias KM, Johnston SA, eds. Veterinary surgery: small animal. St Louis: Saunders Elsevier, 2012;914–920.
25. Laflamme DP. Development and validation of a body condition score system for dogs. Canine Pract 1997; 22: 10–15.
26. McCarthy TC. Synovitis in dogs with stable stifle joints and incipient cranial cruciate ligament rupture (lett). Vet Surg 2012; 41: 540.
27. Hulse D, Beale B, Kerwin S. Second look arthroscopic findings after tibial plateau leveling osteotomy. Vet Surg 2010; 39: 350–354.
28. Innes JF, Costello M, Barr FJ, et al. Radiographic progression of osteoarthritis of the canine stifle joint: a prospective study. Vet Radiol Ultrasound 2004; 45: 143–148.
29. Wilke VL, Zhang S, Evans RB, et al. Identification of chromosomal regions associated with cranial cruciate ligament rupture in a population of Newfoundlands. Am J Vet Res 2009; 70: 1013–1017.
30. Wilke VL, Conzemius MG, Kinghorn BP, et al. Inheritance of rupture of the cranial cruciate ligament in Newfoundlands. J Am Vet Med Assoc 2006; 228: 61–64.
31. de Rooster H, Van Ryssen B, van Bree H. Diagnosis of cranial cruciate ligament injury in dogs by tibial compression radiography. Vet Rec 1998; 142: 366–368.
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Objective—To determine prevalence of the contralateral radiographic infrapatellar fat pad sign and contralateral radiographic degenerative sign (degenerative changes) and evaluate both signs as risk factors for subsequent contralateral cranial cruciate ligament (CrCL) rupture in dogs with unilateral CrCL rupture.
Design—Retrospective cohort study.
Animals—96 dogs with unilateral CrCL rupture and 22 dogs with bilateral CrCL rupture.
Procedures—Dogs with unilateral CrCL rupture were classified as having normal (n = 84) or abnormal (12) contralateral stifle joints on the basis of joint palpation. Associations between potential predictive variables and rates of subsequent contralateral CrCL rupture were evaluated.
Results—Of the 84 dogs with unilateral CrCL rupture in which the contralateral stifle joint was palpably normal, 29 (34.5%) had a contralateral fat pad sign and 31 (36.9%) had a degenerative sign. All dogs with unilateral CrCL rupture in which the contralateral stifle joint was palpably abnormal had a contralateral fat pad sign and degenerative sign. The contralateral fat pad sign was the most important risk factor for subsequent rupture of the contralateral CrCL. For dogs with unilateral CrCL rupture and palpably normal contralateral stifle joint with and without a contralateral fat pad sign, median time to subsequent rupture was 421 and 1,688 days, respectively, and the 3-year probability of subsequent rupture was 85.3% and 24.9%, respectively.
Conclusions and Clinical Relevance—Bilateral stifle joint radiography should be performed for all dogs with CrCL rupture. Bilateral stifle joint arthroscopy should be considered for dogs with a contralateral fat pad sign.
All cases were from the Veterinary Medical and Surgical Group. Radiographic measurements, statistical analysis, and manuscript preparation were performed at the University of California-Davis School of Veterinary Medicine.
Presented in poster form at the 39th Annual Veterinary Orthopedic Society Conference, Crested Butte, Colo, March 2012.