Cover Journal of the American Veterinary Medical Association
Journal of the American Veterinary Medical Association
ISSN:
0003-1488
Publication Date:
01 Nov 2013

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Prevalence of uveal cysts and pigmentary uveitis in Golden Retrievers in three Midwestern states

Wendy M. Townsend DVM, MS, DACVO1 and Kara R. Gornik DVM2
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  • 1 Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47909.
  • | 2 Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824.
DOI:
https://doi.org/10.2460/javma.243.9.1298
Volume/Issue:
Volume 243: Issue 9
Online Publication Date:
01 Nov 2013
Restricted access
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Abstract

Objective—To determine the prevalence of uveal cysts and pigmentary uveitis (PU) in Golden Retrievers in 3 Midwestern states.

Design—Prospective cross-sectional study.

Animals—164 American Kennel Club-registered Golden Retrievers in the states of Illinois, Indiana, and Michigan.

Procedures—For all dogs, biomicroscopic and binocular indirect ophthalmoscopic examinations of both eyes were performed after pupillary dilation. A finding of pigment deposition in a radial pattern or in zones on the anterior aspect of the lens capsule of 1 or both eyes was required for a diagnosis of PU.

Results—Eighty of the 328 (24.4%) eyes and 57 of the 164 (34.8%) dogs had visible uveal cysts. Of those 80 eyes with cysts, 41 (51.3%) had a single cyst located nasally and posterior to the iris, 33 (41.3%) had multiple uveal cysts, and 6 (75%) had a single, free-floating cyst. A diagnosis of PU was made for 9 (5.5%) dogs.

Conclusions and Clinical Relevance—Prevalences of uveal cysts (34.3%) and PU (5.5%) in the examined Golden Retrievers were both higher than prevalences reported previously (5.4% for uveal cysts and 1.5% for PU) in the Canine Eye Registry Foundation's 2009 All-Breeds Report. Study findings have indicated that PU is not a rare condition and should be considered as a differential diagnosis for Golden Retrievers with ocular disease.

Abstract

Objective—To determine the prevalence of uveal cysts and pigmentary uveitis (PU) in Golden Retrievers in 3 Midwestern states.

Design—Prospective cross-sectional study.

Animals—164 American Kennel Club-registered Golden Retrievers in the states of Illinois, Indiana, and Michigan.

Procedures—For all dogs, biomicroscopic and binocular indirect ophthalmoscopic examinations of both eyes were performed after pupillary dilation. A finding of pigment deposition in a radial pattern or in zones on the anterior aspect of the lens capsule of 1 or both eyes was required for a diagnosis of PU.

Results—Eighty of the 328 (24.4%) eyes and 57 of the 164 (34.8%) dogs had visible uveal cysts. Of those 80 eyes with cysts, 41 (51.3%) had a single cyst located nasally and posterior to the iris, 33 (41.3%) had multiple uveal cysts, and 6 (75%) had a single, free-floating cyst. A diagnosis of PU was made for 9 (5.5%) dogs.

Conclusions and Clinical Relevance—Prevalences of uveal cysts (34.3%) and PU (5.5%) in the examined Golden Retrievers were both higher than prevalences reported previously (5.4% for uveal cysts and 1.5% for PU) in the Canine Eye Registry Foundation's 2009 All-Breeds Report. Study findings have indicated that PU is not a rare condition and should be considered as a differential diagnosis for Golden Retrievers with ocular disease.

Contributor Notes

Dr. Gornik's present address is Foster Hospital for Small Animals, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536.

Presented in abstract form at the 42nd Annual Meeting of the American College of Veterinary Ophthalmologists, Hilton Head, SC, October 2011.

Address correspondence to Dr. Townsend (townsenw@purdue.edu).