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Pathology in Practice

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  • 1 Diagnostic Center for Population and Animal Health and Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, Lansing, MI 48910.
  • | 2 Department of Pathology, Faculdade de Medicina Veterinária, Universidade Federal de Santa Maria, Santa Maria, RS 97105-900, Brazil.
  • | 3 Center for Animal Functional Genomics and Molecular Pathogenesis Laboratory, Michigan State University, Lansing, MI 48910.
  • | 4 Center for Animal Functional Genomics and Molecular Pathogenesis Laboratory, Michigan State University, Lansing, MI 48910.
  • | 5 Diagnostic Center for Population and Animal Health and Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, Lansing, MI 48910.
History

A 4-year-old Holstein cow had a history of chronic emaciation and profuse brownish green diarrhea, which was entirely liquid and described as being like water from a hose. The cow was euthanized by an IV overdose sodium pentobarbital injection 5 to 6 weeks after calving because of extreme weakness.

Clinical and Gross Findings

At necropsy, the cow had a body condition score of 2 of 5 and was dehydrated. There was marked loss of muscle mass, serous atrophy of epicardial and perirenal fat depots, and fluid effusion in the abdominal cavity (1.7 L), thoracic cavity (700 mL), and pericardial

Contributor Notes

Address correspondence to Dr. Langohr (langohri@dcpah.msu.edu).