Cover Journal of the American Veterinary Medical Association
Journal of the American Veterinary Medical Association
ISSN:
0003-1488
Publication Date:
15 Jun 2013

  • 1. Buergelt CD, Bastianello SS, Michel AL. Paratuberculosis. In: Coetzer JAW, Tustin RC, eds. Infectious diseases of livestock. Vol 3. 2nd ed. Oxford University Press, 2004; 1994–2008.

    • Search Google Scholar
    • Export Citation

  • 2. Miller LM, Van Vleet JF, Gal A. Cardiovascular system and lymphatic vessels. In: Zachary JF, McGavin MD, eds. Pathologic basis of veterinary disease. 5th ed. St Louis: Mosby-Elsevier, 2012; 539–588.

    • Search Google Scholar
    • Export Citation

  • 3. Mello JRB. Calcinosis—calcinogenic plants. Toxicon 2003; 41: 1–12.

  • 4. Whitlock RH. Diseases of the alimentary tract. In: Smith BP, ed. Large animal internal medicine. 3rd ed. St Louis: Mosby-Elsevier, 2009; 667–893.

    • Search Google Scholar
    • Export Citation

  • 5. Gelberg BH. Alimentary system and the peritoneum, omentum, mesentery, and peritoneal cavity. In: Zachary JF, McGavin MD, eds. Pathologic basis of veterinary disease. 5th ed. St Louis: Mosby-Elsevier, 2012; 322–404.

    • Search Google Scholar
    • Export Citation

  • 6. Valli VEO. Hematopoietic system. In: Maxie MG, ed. Jubb, Kennedy, and Palmer's pathology of domestic animals. Vol 3. 5th ed. Philadelphia: Saunders-Elsevier, 2007; 107–324.

    • Search Google Scholar
    • Export Citation

  • 7. Fitzgerald SD, Sledge DG, Maes R, et al. Coinfection of a cow with bovine leukemia virus and Mycobacterium bovis. J Vet Diagn Invest 2009; 21: 878–882.

    • Search Google Scholar
    • Export Citation

  • 8. Tiwari A, VanLeeuwen JA, McKenna SL, et al. Johne's disease in Canada. Part I: clinical symptoms, pathophysiology, diagnosis, and prevalence in dairy herds. Can Vet J 2006; 47: 874–882.

    • Search Google Scholar
    • Export Citation

  • 9. Weiss DJ, Souza CD. Review paper: modulation of mononuclear phagocyte function by Mycobacterium avium subsp. paratuberculosis. Vet Pathol 2008; 45: 829–841.

    • Search Google Scholar
    • Export Citation

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Editorial Type:
Pathology in Practice

Pathology in Practice

Fábio B. Rosa DVM1,2, Jonathan Roussey BS3, Paul M. Coussens PhD4, and Ingeborg M. Langohr DVM, PhD, DACVP5
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  • 1 Diagnostic Center for Population and Animal Health and Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, Lansing, MI 48910.
  • | 2 Department of Pathology, Faculdade de Medicina Veterinária, Universidade Federal de Santa Maria, Santa Maria, RS 97105-900, Brazil.
  • | 3 Center for Animal Functional Genomics and Molecular Pathogenesis Laboratory, Michigan State University, Lansing, MI 48910.
  • | 4 Center for Animal Functional Genomics and Molecular Pathogenesis Laboratory, Michigan State University, Lansing, MI 48910.
  • | 5 Diagnostic Center for Population and Animal Health and Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, Lansing, MI 48910.
DOI:
https://doi.org/10.2460/javma.242.12.1655
Volume/Issue:
Volume 242: Issue 12
Online Publication Date:
15 Jun 2013
Restricted access
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History

A 4-year-old Holstein cow had a history of chronic emaciation and profuse brownish green diarrhea, which was entirely liquid and described as being like water from a hose. The cow was euthanized by an IV overdose sodium pentobarbital injection 5 to 6 weeks after calving because of extreme weakness.

 Clinical and Gross Findings

At necropsy, the cow had a body condition score of 2 of 5 and was dehydrated. There was marked loss of muscle mass, serous atrophy of epicardial and perirenal fat depots, and fluid effusion in the abdominal cavity (1.7 L), thoracic cavity (700 mL), and pericardial

Contributor Notes

Address correspondence to Dr. Langohr (langohri@dcpah.msu.edu).