Evaluation of heart murmurs in chinchillas (Chinchilla lanigera): 59 cases (1996–2009)

Charly Pignon Exotics Medicine Service, Centre hospitalier vétérinaire universitaire d'Alfort, École nationale vétérinaire d'Alfort, Maisons-Alfort, France.

Search for other papers by Charly Pignon in
Current site
Google Scholar
PubMed
Close
 DVM
,
David Sanchez-Migallon Guzman Special Species Health Service, Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706.

Search for other papers by David Sanchez-Migallon Guzman in
Current site
Google Scholar
PubMed
Close
 LV, MS, DACZM
,
Kristen Sinclair William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616.

Search for other papers by Kristen Sinclair in
Current site
Google Scholar
PubMed
Close
 DVM
,
Charlotte Baey Service de biostatistique et epidémiologie, Institut de cancérologie Gustave-Roussy, Villejuif, France.

Search for other papers by Charlotte Baey in
Current site
Google Scholar
PubMed
Close
 MSc
,
Jean-Pierre Pignon Service de biostatistique et epidémiologie, Institut de cancérologie Gustave-Roussy, Villejuif, France.

Search for other papers by Jean-Pierre Pignon in
Current site
Google Scholar
PubMed
Close
 MD, PhD
,
Joerg Mayer Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.

Search for other papers by Joerg Mayer in
Current site
Google Scholar
PubMed
Close
 Dr Vet Med, MSc, DABVP
,
Mark D. Kittleson Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616.

Search for other papers by Mark D. Kittleson in
Current site
Google Scholar
PubMed
Close
 DVM, PhD, DACVIM
, and
Joanne Paul-Murphy Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616.
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.

Search for other papers by Joanne Paul-Murphy in
Current site
Google Scholar
PubMed
Close
 DVM, DACZM, DACAW

Abstract

Objective—To determine the prevalence of heart murmurs in chinchillas (Chinchilla lanigera) and determine whether heart murmurs were associated with cardiac disease.

Design—Retrospective multi-institutional case series.

Animals—260 chinchillas.

Procedures—Medical records of all chinchilla patients evaluated at the Tufts University Foster Hospital for Small Animals between 2001 and 2009, the University of California-Davis William R. Pritchard Veterinary Medical Teaching Hospital between 1996 and 2009, and the University of Wisconsin Veterinary Medical Teaching Hospital between 1998 and 2009 were reviewed.

Results—Prevalence of heart murmurs was 23% (59/260). Of 15 chinchillas with heart murmurs that underwent echocardiography, 8 had echocardiographic abnormalities, including dynamic right ventricular outflow tract obstruction, mitral regurgitation, hypertrophy of the left ventricle, tricuspid regurgitation, and hypovolemia. Echocardiographic abnormalities were approximately 29 times as likely (OR, 28.7) to be present in chinchillas with a murmur of grade 3 or higher than in chinchillas without a murmur.

Conclusions and Clinical Relevance—Results suggested that heart murmurs are common in chinchillas and that chinchillas with heart murmurs often have echocardiographic abnormalities, with valvular disease being the most common. On the basis of these results, we believe that echocardiography should be recommended for chinchillas with heart murmurs, especially older chinchillas with murmurs of grade 3 or higher. Further prospective studies are needed to accurately evaluate the prevalence of cardiac disease in chinchillas with heart murmurs.

Abstract

Objective—To determine the prevalence of heart murmurs in chinchillas (Chinchilla lanigera) and determine whether heart murmurs were associated with cardiac disease.

Design—Retrospective multi-institutional case series.

Animals—260 chinchillas.

Procedures—Medical records of all chinchilla patients evaluated at the Tufts University Foster Hospital for Small Animals between 2001 and 2009, the University of California-Davis William R. Pritchard Veterinary Medical Teaching Hospital between 1996 and 2009, and the University of Wisconsin Veterinary Medical Teaching Hospital between 1998 and 2009 were reviewed.

Results—Prevalence of heart murmurs was 23% (59/260). Of 15 chinchillas with heart murmurs that underwent echocardiography, 8 had echocardiographic abnormalities, including dynamic right ventricular outflow tract obstruction, mitral regurgitation, hypertrophy of the left ventricle, tricuspid regurgitation, and hypovolemia. Echocardiographic abnormalities were approximately 29 times as likely (OR, 28.7) to be present in chinchillas with a murmur of grade 3 or higher than in chinchillas without a murmur.

Conclusions and Clinical Relevance—Results suggested that heart murmurs are common in chinchillas and that chinchillas with heart murmurs often have echocardiographic abnormalities, with valvular disease being the most common. On the basis of these results, we believe that echocardiography should be recommended for chinchillas with heart murmurs, especially older chinchillas with murmurs of grade 3 or higher. Further prospective studies are needed to accurately evaluate the prevalence of cardiac disease in chinchillas with heart murmurs.

Contributor Notes

Dr. Guzman's present address is Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616.

Address correspondence to Dr. Sanchez-Migallon Guzman (guzman@ucdavis.edu).
  • 1.

    Quesenberry KE, Donnelly TM, Hillyer EV. Biology, husbandry and clinical techniques of guinea pigs and chinchillas. In: Quesenberry KE, Carpenter JW, eds. Ferrets, rabbits, and rodents: clinical medicine and surgery. 2nd ed. Philadelphia: WB Saunders Co, 2004; 232245.

    • Search Google Scholar
    • Export Citation
  • 2.

    Walker EP. Mammals of the world. Vol II. 3rd ed. Baltimore: Johns Hopkins University Press, 1975.

  • 3.

    Ritchey L, Cogswell M. The joy of chinchillas. 3rd ed. Menlo Park, Calif: California Chinchilla Association, 1995; 2637.

  • 4.

    Donnelly TM. Disease problems of the chinchillas. In: Quesenberry KE, Carpenter JW, eds. Ferrets, rabbits, and rodents: clinical medicine and surgery. Philadelphia: WB Saunders Co, 2004; 255265.

    • Search Google Scholar
    • Export Citation
  • 5.

    Hoefer HL, Crossley DA. Chinchillas. In: Meredith A, Redrobe S, eds. BSAVA manual of exotic pets. 4th ed. Quedgeley, Gloucester, England: British Small Animal Veterinary Association, 2002; 6575.

    • Search Google Scholar
    • Export Citation
  • 6.

    Linde A, Summerfield NJ, Johnston M, et al. Echocardiography in the chinchilla. J Vet Intern Med 2004; 18: 772774.

  • 7.

    Prosek R. Abnormal heart sounds and hearts murmurs. In: Ettinger SJ, Feldman EC, eds. Textbook of veterinary internal medicine. 6th ed. St Louis: Elsevier Saunders, 2005;195.

    • Search Google Scholar
    • Export Citation
  • 8.

    Côté E, Manning AM, Emerson D, et al. Assessment of the prevalence of heart murmurs in overtly healthy cats. J Am Vet Med Assoc 2004; 225: 384388.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Häggström J, Kvart C, Pedersen HD. Acquired valvular heart disease. In: Ettinger SJ, Feldman EC, eds. Textbook of veterinary internal medicine. 6th ed. St Louis: Elsevier Saunders, 2005;1022.

    • Search Google Scholar
    • Export Citation
  • 10.

    Pariaut R. Cardiovascular physiology and diseases of the rabbit. Vet Clin North Am Exot Anim Pract 2009; 12: 135144.

  • 11.

    Wagner RA. Ferret cardiology. Vet Clin North Am Exot Anim Pract 2009; 12: 115134.

  • 12.

    Harpster NK. Cardiovascular diseases. In: Holzworth J, ed. Diseases of the cat: medicine and surgery. Philadelphia: WB Saunders Co, 1987; 820933.

    • Search Google Scholar
    • Export Citation
  • 13.

    Bonagura JD. Cardiovascular diseases. In: Sherding RG, ed. The cat: diseases and clinical management. 2nd ed. St Louis: Churchill Livingstone Inc, 1994;824.

    • Search Google Scholar
    • Export Citation

Advertisement