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Update on drugs prohibited from extralabel use in food animals

Jennifer L. Davis DVM, PhD, DACVIM, DACVCP1, Geof W. Smith DVM, PhD, DACVIM2, Ronald E. Baynes DVM, PhD3, Lisa A. Tell DVM, DABVP, DACZM4, Alistair I. Webb BVSc, PhD, DACVA5, and Jim E. Riviere DVM, PhD6
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  • 1 Food Animal Residue Avoidance Databank, Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606.
  • | 2 Food Animal Residue Avoidance Databank, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606.
  • | 3 Food Animal Residue Avoidance Databank, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606.
  • | 4 Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616.
  • | 5 Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610.
  • | 6 Food Animal Residue Avoidance Databank, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606.

Extralabel drug use encompasses the use of a drug in an animal in a manner that is not in accordance with the FDA-approved label. This includes use in a species or for a disease or condition not listed on the label; use at dosages, frequencies, or routes of administration that differ from those stated on the label; or deviation from the labeled withdrawal time. Extralabel drug use in veterinary species was made legal by the passage of AMDUCA in 1994.1 However, there are restrictions to AMDUCA, particularly with reference to ELDU in food-producing animals.

The information reported here

Contributor Notes

Address correspondence to Dr. Davis.