Burkholder WJ, Toll PW. Obesity. In: Hand MS, Thatcher CD, Reimillard RL, et al, eds. Small animal clinical nutrition. 4th ed. Marceline, Mo: Walsworth Publishing Co, 2000;401–430.
Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999–2000. JAMA 2002;288:1723–1727.
Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of over-weight and obesity in the United States, 1999–2004. JAMA 2006;295:1549–1555.
McGreevy PD, Thomson C, Pride C, et al. Prevalence of obesity in dogs examined by Australian veterinary practices and the risk factors involved. Vet Rec 2005;156:695–702.
Mason E. Obesity in pet dogs. Vet Rec 1970;86:612–616.
Lund EM, Armstrong PJ, Kirk CA, et al. Prevalence and risk factors for obesity in adult dogs from private US veterinary practices. Intern J Appl Res Vet Med 2006;4:177–186.
Laflamme DP. Understanding and managing obesity in dogs and cats. Vet Clin North Am Small Anim Pract 2006;36:1283–1295.
Burkholder WJ, Bauer JE. Foods and techniques for managing obesity in companion animals. J Am Vet Med Assoc 1998;212:658–662.
Allison DB, Fontaine KR, Heshka S, et al. Alternative treatments for weight loss: a critical review. Crit Rev Food Sci Nutr 2001;41:1–28.
Sunvold GD. A new nutritional paradigm for weight management. In: Reinhart GA, Carey DP, eds. Current perspectives in weight management. Dayton, Ohio: The Iams Co, 2001;29–35.
Wang Y, Jones PJ. Dietary conjugated linoleic acid and body composition. Am J Clin Nutr 2004;79:1153S–1158S.
Terpstra AH. Effect of conjugated linoleic acid on body composition and plasma lipids in humans: an overview of the literature. Am J Clin Nutr 2004;79:352–361.
Bhathena SJ, Velasquez MT. Beneficial role of dietary phytoestrogens in obesity and diabetes. Am J Clin Nutr 2002;76:1191–1201.
Bauer JE, Maskell IE. Dietary fibre: perspectives in clinical management. In: Wills JM, Simpson KW, eds. The Waltham book of clinical nutrition of the dog and cat. New York: Elsevier, 1994;87–104.
Aleixandre A, Miguel M. Dietary fiber in the prevention and treatment of metabolic syndrome: a review. Crit Rev Food Sci Nutr 2000;48:905–912.
Van Itallie TB. Dietary fiber and obesity. Am J Clin Nutr 1978;31:S43–S52.
Gee JM, Blackburn NA, Johnson IT. The influence of guar gum on intestinal cholesterol transport in the rat. Br J Nutr 1983;50:215–224.
Fahey GC, Flicklinger EA, Grieshop CM, et al. The role of dietary fibre in companion animal nutrition, in Proceedings. Dietary Fiber 2003 Conf 2004;295–315.
Butterwick RF, Markwell PJ. Effect of amount and type of dietary fiber on food intake in energy-restricted dogs. Am J Vet Res 1997;58:272–276.
Eastwood MA, Hamilton D. Studies on the adsorption of bile salts to non-absorbed components of diet. Biochim Biophys Acta 1968;152:165–173.
Kritchevsky D, Story JA. Binding of bile salts in vitro by nonnutritive fiber. J Nutr 1974;104:458–462.
Chen WJ, Anderson JW. Effects of plant fiber in decreasing plasma total cholesterol and increasing high-density lipoprotein cholesterol. Proc Soc Exp Biol Med 1979;162:310–313.
Pasman WJ, Saris WH, Wauters MA, et al. Effect of one week of fibre supplementation on hunger and satiety ratings and energy intake. Appetite 1997;29:77–87.
Holt S, Brand J, Soveny C, et al. Relationship of satiety to post-prandial glycaemic, insulin and cholecystokinin responses. Appetite 1992;18:129–141.
Salas-Salvadó J, Farrés X, Luque X, et al. Effect of two doses of a mixture of soluble fibres on body weight and metabolic variables in overweight or obese patients: a randomised trial. Br J Nutr 2008;99:1380–1387.
Anderson JW, Story L, Sieling B, et al. Hypercholesterolemic effects of oat-bran or bean intake for hypercholesterolemic men. Am J Clin Nutr 1984;40:1146–1155.
Birketvedt GS, Aaseth J, Florholmen JR, et al. Long-term effect of fibre supplement and reduced energy intake on body weight and blood lipids in overweight subjects. Acta Medica (Hradec Kralove) 2000;43:129–132.
Howarth NC, Saltzman E, McCrory MA, et al. Fermentable and nonfermentable fiber supplements did not alter hunger, satiety or body weight in a pilot study of men and women consuming self-selected diets. J Nutr 2003;133:3141–3144.
Hays NP, Starling RD, Liu X, et al. Effects of an ad libitum low-fat, high-carbohydrate diet on body weight, body composition, and fat distribution in older men and women: a randomized controlled trial. Arch Intern Med 2004;164:210–217.
Rolls BJ, Ello-Martin JA, Tohill BC. What can intervention studies tell us about the relationship between fruit and vegetable consumption and weight management? Nutr Rev 2004;62:1–17.
Howarth NC, Saltzman E, Roberts SB. Dietary fiber and weight regulation. Nutr Rev 2001;59:129–139.
Yamamoto Y. Hypolipidemic effects of a guar gum-xanthan gum mixture in rats fed high sucrose diets. J Jpn Soc Nutr Food Sci 2003;54:139–145.
Southgate DA, Branch WJ, Hill MJ, et al. Metabolic responses to dietary supplements of bran. Metabolism 1976;25:1129–1135.
Kay RM. Dietary fiber. J Lipid Res 1982;23:221–242.
Elsenhans B, Süfke U, Blume R, et al. The influence of carbohydrate gelling agents on rat intestinal transport of monosaccharides and neutral amino acids in vitro. Clin Sci 1980;59:373–380.
Borel P, Lairon D, Senft M, et al. Wheat bran and wheat germ: effect on digestion and intestinal absorption of dietary lipids in the rat. Am J Clin Nutr 1989;49:1192–1202.
Fahey GC, Merchen NR, Corbin JE, et al. Dietary fiber for dogs: I. Effects of graded levels of dietary beet pulp on nutrient intake, digestibility, metabolizable energy and digesta mean retention time. J Anim Sci 1990;68:4221–4228.
Butterwick RF, Markwell PJ, Thorne CJ. Effect of level and source of dietary fiber on food intake in the dog. J Nutr 1994;124:2695S–2700S.
Jackson JE, Laflamme DP, Owens SF. Effects of dietary fiber content on satiety in dogs. Vet Clin Nutr 1997;4:130–134.
Jewell DE, Toll PW. Effects of fiber on food intake in dogs. Vet Clin Nutr 1996;3:115–118.
Jewell DE, Toll PW, Novotny BJ. Satiety reduces adiposity in dogs. Vet Ther 2000;1:17–23.
Weber M, Bissot T, Servet E, et al. A high-protein, high-fiber diet designed for weight loss improves satiety in dogs. J Vet Intern Med 2007;21:1203–1208.
Bosch G, Verbrugghe A, Hesta M, et al. The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs. Br J Nutr 2009;102:318–325.
Abdel-Nabey AA, Shehata Y, Ragab MH, et al. Glycerides of cottonseed oils from Egyptian and other varieties. Riv Ital Sostanze Grasse 1992;69:443–447.
D'alonzo RP, Kozarek WJ, Wade RL. Glyceride composition of processed fats and oils as determined by glass capillary gas chromatography. J Am Oil Chem Soc 1982;59:292–295.
Nakajima Y, Fukasawa J, Shimada A. Physicochemical properties of diacylglycerol. In: Yasukawa T, Katsuragi Y, eds. Diacylglycerol oil. Champaign, Ill: AOCS Press, 2004;182–207.
Matsuo N. The purpose and summary of diacylglycerol research. In: Igarashi O, Ikemoto S, Itakura H, et al, eds. The functions and nutrition of DAG [in Japanese]. Tokyo: Saiwaishobo, 2007;7–35.
White DA, Bennett AJ, Billett MA, et al. The assembly of triacylglycerol-rich lipoproteins: an essential role for the microsomal triacylglycerol transfer protein. Br J Nutr 1998;80:219–229.
Yang LY, Kuksis A. Apparent convergence (at 2-monoacylglycerol level) of phosphatidic acid and 2-monoacylglycerol pathways of synthesis of chylomicron triacylglycerols. J Lipid Res 1991;32:1173–1186.
Dyck DJ. Dietary fat intake, supplements, and weight loss. Can J Appl Physiol 2000;25:495–523.
Kondo H, Hase T, Murase T, et al. Digestion and assimilation features of dietary DAG in rat small intestine. Lipids 2003;38:25–30.
Cao J, Lockwood J, Burn P, et al. Cloning and functional characterization of a mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. J Biol Chem 2003;278:13860–13866.
Cheng D, Nelson TC, Chen J, et al. Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption. J Biol Chem 2003;278:13611–13614.
Ikeda I, Yanagida T. Digestion and absorption of diacylglycerol. In: Igarashi O, Ikemoto S, Itakura H, et al, eds. The functions and nutrition of DAG [in Japanese]. Tokyo: Saiwaishobo, 2007;45–54.
Yanagita T, Ikeda T, Wang YM, et al. Comparison of the lymphatic transport of radiolabled 1,3-dioleoylglycerol and trioleoylglyerol in rats. Lipids 2004;29:827–832.
Yasunaga K, Saito S, Zhang Y, et al. Effects of triacylglycerol and diacylglycerol oils on blood clearance tissue uptake, and hepatic apolipoprotein ≤ secretion in mice. J Lipid Res 2007;48:1108–1121.
Kim HJ, Lee KT, Lee MK, et al. Hypolipidemic effect of dietary diacylglycerol oil in Sprague-Dawley rats fed a normal diet. J Med Food 2007;10:60–66.
Datz CA, Backus RC, Fritsche KL. Dietary diacylglycerol oil has no effect on hypertriacylglycerolaemia in lipoprotein lipase-deficient cats. Br J Nutr 2009;102:1024–1029.
Yamamoto K, Asakawa H, Tokunaga K, et al. Effects of diacylglycerol administration on serum triacylglycerol in a patient homozygous for complete lipoprotein lipase deletion. Metabolism 2005;54:67–71.
Hara K, Onizawa K, Honda H, et al. Dietary diacylglycerol-dependent reduction in serum triacylglycerol concentration in rats. Ann Nutr Metab 1993;37:185–191.
Taguchi H, Watanabe H, Onizawa K, et al. Double-blind controlled study on the effects of dietary diacylglycerol on post-prandial serum and chylomicron triacylglycerol responses in healthy humans. J Am Coll Nutr 2000;19:789–796.
Murase T, Nagasawa A, Suzuki J, et al. Dietary alpha-linolenic acid-rich diacylglycerols reduce body weight gain accompanying the stimulation of intestinal beta-oxidation and related gene expressions in C57BL/KsJ-db/db mice. J Nutr 2002;132:3018–3022.
Meng X, Zou D, Shi Z, et al. Dietary diacylglycerol prevents high-fat diet-induced lipid accumulation in rat liver and abdominal adipose tissue. Lipids 2004;39:37–41.
Murata M, Ide T, Hara K. Reciprocal responses to dietary diacylglycerol of hepatic enzymes of fatty acid synthesis and oxidation in the rat. Br J Nutr 1997;77:107–121.
Maki KC, Davidson MH, Tsushima R, et al. Consumption of diacylglycerol oil as part of a reduced-energy diet enhances loss of body weight and fat in comparison with consumption of a triacylglycerol control oil. Am J Clin Nutr 2002;76:1230–1236.
Nagao T, Watanabe H, Goto N, et al. Dietary diacylglycerol suppresses accumulation of body fat compared to triacylglycerol in men in a double-blind controlled trial. J Nutr 2000;130:792–797.
Murase T, Mizuno T, Omachi T, et al. Dietary diacylglycerol suppresses high fat and high sucrose diet-induced body fat accumulation in C57BL/6J mice. J Lipid Res 2001;42:372–378.
Umeda T, Bauer JE, Otsuji K. Weight loss effect of dietary diacylglycerol in obese dogs. J Anim Physiol Anim Nutr (Berl) 2006;90:208–216.
Yasunaga K, Glinsmann WH, Seo Y, et al. Safety aspects regarding the consumption of high-dose dietary diacylglycerol oil in men and women in a double-blind controlled trial in comparison with consumption of a triacylglycerol control oil. Food Chem Toxicol 2004;42:1419–1429.
Soni MG, Kimura H, Burdock GA. Chronic study of diacylglycerol oil in rats. Food Chem Toxicol 2001;39:317–329.
Kasamatsu T, Ogura R, Ikeda N, et al. Genotoxicity studies on dietary diacylglycerol (DAG) oil. Food Chem Toxicol 2005;43:253–260.
Chengelis CP, Kirkpatrick JB, Marit GB, et al. A chronic dietary toxicity study of DAG (diacylglycerol) in Beagle dogs. Food Chem Toxicol 2006;44:81–97.
Wolever TMS. The glycemic index: methodology and clinical implications. Am J Clin Nutr 1991;54:846–854.
Brand JC, Nicholson PL, Thorburn AW, et al. Food processing and the glycemic index. Am J Clin Nutr 1985;42:1192–1196.
Jenkins DJ, Ghafari H, Wolever TM, et al. Relationship between rate of digestion of foods and post-prandial glycaemia. Diabetologia 1982;22:450–455.
Wolever TM. Relationship between dietary fiber content and composition in foods and the glycemic index. Am J Clin Nutr 1990;51:72–75.
Behall KM, Scholfield DJ, Canary J. Effect of starch structure on glucose and insulin responses in adults. Am J Clin Nutr 1988;47:428–432.
Hallfrisch J, Behall KM. Mechanisms of the effects of grains on insulin and glucose responses. J Am Coll Nutr 2000;19:320S–325S.
Wheeler ML, Pi-Sunyer FX. Carbohydrate issues: type and amount. J Am Diet Assoc 2008;108:S34–S39.
Jenkins DJ, Wolever TM, Taylor RH. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 1981;34:362–366.
Thomas DE, Elliott EJ, Bauer L. Low glycemic index or low glycemic load diets for overweight and obesity. Cochrane Database Syst Rev 2007;18:CD005105.
Brand-Miller JC, Holt SH, Paelak DB, et al. Glycemic index and obesity. Am J Clin Nutr 2002;76:281S–285S.
Kabir M, Rizkalla SW, Quignard-Boulangé A, et al.A high glycemic index starch diet affects lipid storage-related enzymes in normal and to a lesser extent in diabetic rats. J Nutr 1998;128:1878–1883.
Pawlak DB, Kushner JA, Ludwig DS. Effects of dietary glycaemic index on adiposity, glucose homoeostasis, and plasma lipids in animals. Lancet 2004;364:778–785.
Bouché C, Rizkalla SW, Luo J, et al. Five-week, low-glycemic index diet decreases total fat mass and improves plasma lipid profile in moderately overweight nondiabetic men. Diabetes Care 2002;25:822–828.
de Rougemont A, Normand S, Nazare JA, et al. Beneficial effects of a 5-week low-glycaemic index regimen on weight control and cardiovascular risk factors in overweight non-diabetic subjects. Br J Nutr 2007;98:1288–1298.
Philippou E, Neary NM, Chaudhri O, et al. The effect of dietary glycemic index on weight maintenance in overweight subjects: a pilot study. Obesity (Silver Spring) 2009;17:396–401.
Sichieri R, Moura AS, Genelhu V, et al. An 18-mo randomized trial of a low-glycemic-index diet and weight change in Brazilian women. Am J Clin Nutr 2007;86:707–713.
Raatz SK, Torkelson CJ, Redmon JB, et al. Reduced glycemic index and glycemic load diets do not increase the effects of energy restriction on weight loss and insulin sensitivity in obese men and women. J Nutr 2005;135:2387–2391.
Nguyen P, Dumon H, Biourge V, et al. Glycemic and insulinemic responses after ingestion of commercial foods in healthy dogs: influence of food composition. J Nutr 1998;128:2654S–2658S.
Bauer JE, Nagaoka D, Porterpan B, et al. Postprandial lipolytic activities, lipids and carbohydrate metabolism are altered in dogs fed diacylglycerol meals containing high- and low-glycemic index starches. J Nutr 2006;136:1955S–1957S.
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Burkholder WJ, Toll PW. Obesity. In: Hand MS, Thatcher CD, Reimillard RL, et al, eds. Small animal clinical nutrition. 4th ed. Marceline, Mo: Walsworth Publishing Co, 2000;401–430.
Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999–2000. JAMA 2002;288:1723–1727.
Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of over-weight and obesity in the United States, 1999–2004. JAMA 2006;295:1549–1555.
McGreevy PD, Thomson C, Pride C, et al. Prevalence of obesity in dogs examined by Australian veterinary practices and the risk factors involved. Vet Rec 2005;156:695–702.
Mason E. Obesity in pet dogs. Vet Rec 1970;86:612–616.
Lund EM, Armstrong PJ, Kirk CA, et al. Prevalence and risk factors for obesity in adult dogs from private US veterinary practices. Intern J Appl Res Vet Med 2006;4:177–186.
Laflamme DP. Understanding and managing obesity in dogs and cats. Vet Clin North Am Small Anim Pract 2006;36:1283–1295.
Burkholder WJ, Bauer JE. Foods and techniques for managing obesity in companion animals. J Am Vet Med Assoc 1998;212:658–662.
Allison DB, Fontaine KR, Heshka S, et al. Alternative treatments for weight loss: a critical review. Crit Rev Food Sci Nutr 2001;41:1–28.
Sunvold GD. A new nutritional paradigm for weight management. In: Reinhart GA, Carey DP, eds. Current perspectives in weight management. Dayton, Ohio: The Iams Co, 2001;29–35.
Wang Y, Jones PJ. Dietary conjugated linoleic acid and body composition. Am J Clin Nutr 2004;79:1153S–1158S.
Terpstra AH. Effect of conjugated linoleic acid on body composition and plasma lipids in humans: an overview of the literature. Am J Clin Nutr 2004;79:352–361.
Bhathena SJ, Velasquez MT. Beneficial role of dietary phytoestrogens in obesity and diabetes. Am J Clin Nutr 2002;76:1191–1201.
Bauer JE, Maskell IE. Dietary fibre: perspectives in clinical management. In: Wills JM, Simpson KW, eds. The Waltham book of clinical nutrition of the dog and cat. New York: Elsevier, 1994;87–104.
Aleixandre A, Miguel M. Dietary fiber in the prevention and treatment of metabolic syndrome: a review. Crit Rev Food Sci Nutr 2000;48:905–912.
Van Itallie TB. Dietary fiber and obesity. Am J Clin Nutr 1978;31:S43–S52.
Gee JM, Blackburn NA, Johnson IT. The influence of guar gum on intestinal cholesterol transport in the rat. Br J Nutr 1983;50:215–224.
Fahey GC, Flicklinger EA, Grieshop CM, et al. The role of dietary fibre in companion animal nutrition, in Proceedings. Dietary Fiber 2003 Conf 2004;295–315.
Butterwick RF, Markwell PJ. Effect of amount and type of dietary fiber on food intake in energy-restricted dogs. Am J Vet Res 1997;58:272–276.
Eastwood MA, Hamilton D. Studies on the adsorption of bile salts to non-absorbed components of diet. Biochim Biophys Acta 1968;152:165–173.
Kritchevsky D, Story JA. Binding of bile salts in vitro by nonnutritive fiber. J Nutr 1974;104:458–462.
Chen WJ, Anderson JW. Effects of plant fiber in decreasing plasma total cholesterol and increasing high-density lipoprotein cholesterol. Proc Soc Exp Biol Med 1979;162:310–313.
Pasman WJ, Saris WH, Wauters MA, et al. Effect of one week of fibre supplementation on hunger and satiety ratings and energy intake. Appetite 1997;29:77–87.
Holt S, Brand J, Soveny C, et al. Relationship of satiety to post-prandial glycaemic, insulin and cholecystokinin responses. Appetite 1992;18:129–141.
Salas-Salvadó J, Farrés X, Luque X, et al. Effect of two doses of a mixture of soluble fibres on body weight and metabolic variables in overweight or obese patients: a randomised trial. Br J Nutr 2008;99:1380–1387.
Anderson JW, Story L, Sieling B, et al. Hypercholesterolemic effects of oat-bran or bean intake for hypercholesterolemic men. Am J Clin Nutr 1984;40:1146–1155.
Birketvedt GS, Aaseth J, Florholmen JR, et al. Long-term effect of fibre supplement and reduced energy intake on body weight and blood lipids in overweight subjects. Acta Medica (Hradec Kralove) 2000;43:129–132.
Howarth NC, Saltzman E, McCrory MA, et al. Fermentable and nonfermentable fiber supplements did not alter hunger, satiety or body weight in a pilot study of men and women consuming self-selected diets. J Nutr 2003;133:3141–3144.
Hays NP, Starling RD, Liu X, et al. Effects of an ad libitum low-fat, high-carbohydrate diet on body weight, body composition, and fat distribution in older men and women: a randomized controlled trial. Arch Intern Med 2004;164:210–217.
Rolls BJ, Ello-Martin JA, Tohill BC. What can intervention studies tell us about the relationship between fruit and vegetable consumption and weight management? Nutr Rev 2004;62:1–17.
Howarth NC, Saltzman E, Roberts SB. Dietary fiber and weight regulation. Nutr Rev 2001;59:129–139.
Yamamoto Y. Hypolipidemic effects of a guar gum-xanthan gum mixture in rats fed high sucrose diets. J Jpn Soc Nutr Food Sci 2003;54:139–145.
Southgate DA, Branch WJ, Hill MJ, et al. Metabolic responses to dietary supplements of bran. Metabolism 1976;25:1129–1135.
Kay RM. Dietary fiber. J Lipid Res 1982;23:221–242.
Elsenhans B, Süfke U, Blume R, et al. The influence of carbohydrate gelling agents on rat intestinal transport of monosaccharides and neutral amino acids in vitro. Clin Sci 1980;59:373–380.
Borel P, Lairon D, Senft M, et al. Wheat bran and wheat germ: effect on digestion and intestinal absorption of dietary lipids in the rat. Am J Clin Nutr 1989;49:1192–1202.
Fahey GC, Merchen NR, Corbin JE, et al. Dietary fiber for dogs: I. Effects of graded levels of dietary beet pulp on nutrient intake, digestibility, metabolizable energy and digesta mean retention time. J Anim Sci 1990;68:4221–4228.
Butterwick RF, Markwell PJ, Thorne CJ. Effect of level and source of dietary fiber on food intake in the dog. J Nutr 1994;124:2695S–2700S.
Jackson JE, Laflamme DP, Owens SF. Effects of dietary fiber content on satiety in dogs. Vet Clin Nutr 1997;4:130–134.
Jewell DE, Toll PW. Effects of fiber on food intake in dogs. Vet Clin Nutr 1996;3:115–118.
Jewell DE, Toll PW, Novotny BJ. Satiety reduces adiposity in dogs. Vet Ther 2000;1:17–23.
Weber M, Bissot T, Servet E, et al. A high-protein, high-fiber diet designed for weight loss improves satiety in dogs. J Vet Intern Med 2007;21:1203–1208.
Bosch G, Verbrugghe A, Hesta M, et al. The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs. Br J Nutr 2009;102:318–325.
Abdel-Nabey AA, Shehata Y, Ragab MH, et al. Glycerides of cottonseed oils from Egyptian and other varieties. Riv Ital Sostanze Grasse 1992;69:443–447.
D'alonzo RP, Kozarek WJ, Wade RL. Glyceride composition of processed fats and oils as determined by glass capillary gas chromatography. J Am Oil Chem Soc 1982;59:292–295.
Nakajima Y, Fukasawa J, Shimada A. Physicochemical properties of diacylglycerol. In: Yasukawa T, Katsuragi Y, eds. Diacylglycerol oil. Champaign, Ill: AOCS Press, 2004;182–207.
Matsuo N. The purpose and summary of diacylglycerol research. In: Igarashi O, Ikemoto S, Itakura H, et al, eds. The functions and nutrition of DAG [in Japanese]. Tokyo: Saiwaishobo, 2007;7–35.
White DA, Bennett AJ, Billett MA, et al. The assembly of triacylglycerol-rich lipoproteins: an essential role for the microsomal triacylglycerol transfer protein. Br J Nutr 1998;80:219–229.
Yang LY, Kuksis A. Apparent convergence (at 2-monoacylglycerol level) of phosphatidic acid and 2-monoacylglycerol pathways of synthesis of chylomicron triacylglycerols. J Lipid Res 1991;32:1173–1186.
Dyck DJ. Dietary fat intake, supplements, and weight loss. Can J Appl Physiol 2000;25:495–523.
Kondo H, Hase T, Murase T, et al. Digestion and assimilation features of dietary DAG in rat small intestine. Lipids 2003;38:25–30.
Cao J, Lockwood J, Burn P, et al. Cloning and functional characterization of a mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. J Biol Chem 2003;278:13860–13866.
Cheng D, Nelson TC, Chen J, et al. Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption. J Biol Chem 2003;278:13611–13614.
Ikeda I, Yanagida T. Digestion and absorption of diacylglycerol. In: Igarashi O, Ikemoto S, Itakura H, et al, eds. The functions and nutrition of DAG [in Japanese]. Tokyo: Saiwaishobo, 2007;45–54.
Yanagita T, Ikeda T, Wang YM, et al. Comparison of the lymphatic transport of radiolabled 1,3-dioleoylglycerol and trioleoylglyerol in rats. Lipids 2004;29:827–832.
Yasunaga K, Saito S, Zhang Y, et al. Effects of triacylglycerol and diacylglycerol oils on blood clearance tissue uptake, and hepatic apolipoprotein ≤ secretion in mice. J Lipid Res 2007;48:1108–1121.
Kim HJ, Lee KT, Lee MK, et al. Hypolipidemic effect of dietary diacylglycerol oil in Sprague-Dawley rats fed a normal diet. J Med Food 2007;10:60–66.
Datz CA, Backus RC, Fritsche KL. Dietary diacylglycerol oil has no effect on hypertriacylglycerolaemia in lipoprotein lipase-deficient cats. Br J Nutr 2009;102:1024–1029.
Yamamoto K, Asakawa H, Tokunaga K, et al. Effects of diacylglycerol administration on serum triacylglycerol in a patient homozygous for complete lipoprotein lipase deletion. Metabolism 2005;54:67–71.
Hara K, Onizawa K, Honda H, et al. Dietary diacylglycerol-dependent reduction in serum triacylglycerol concentration in rats. Ann Nutr Metab 1993;37:185–191.
Taguchi H, Watanabe H, Onizawa K, et al. Double-blind controlled study on the effects of dietary diacylglycerol on post-prandial serum and chylomicron triacylglycerol responses in healthy humans. J Am Coll Nutr 2000;19:789–796.
Murase T, Nagasawa A, Suzuki J, et al. Dietary alpha-linolenic acid-rich diacylglycerols reduce body weight gain accompanying the stimulation of intestinal beta-oxidation and related gene expressions in C57BL/KsJ-db/db mice. J Nutr 2002;132:3018–3022.
Meng X, Zou D, Shi Z, et al. Dietary diacylglycerol prevents high-fat diet-induced lipid accumulation in rat liver and abdominal adipose tissue. Lipids 2004;39:37–41.
Murata M, Ide T, Hara K. Reciprocal responses to dietary diacylglycerol of hepatic enzymes of fatty acid synthesis and oxidation in the rat. Br J Nutr 1997;77:107–121.
Maki KC, Davidson MH, Tsushima R, et al. Consumption of diacylglycerol oil as part of a reduced-energy diet enhances loss of body weight and fat in comparison with consumption of a triacylglycerol control oil. Am J Clin Nutr 2002;76:1230–1236.
Nagao T, Watanabe H, Goto N, et al. Dietary diacylglycerol suppresses accumulation of body fat compared to triacylglycerol in men in a double-blind controlled trial. J Nutr 2000;130:792–797.
Murase T, Mizuno T, Omachi T, et al. Dietary diacylglycerol suppresses high fat and high sucrose diet-induced body fat accumulation in C57BL/6J mice. J Lipid Res 2001;42:372–378.
Umeda T, Bauer JE, Otsuji K. Weight loss effect of dietary diacylglycerol in obese dogs. J Anim Physiol Anim Nutr (Berl) 2006;90:208–216.
Yasunaga K, Glinsmann WH, Seo Y, et al. Safety aspects regarding the consumption of high-dose dietary diacylglycerol oil in men and women in a double-blind controlled trial in comparison with consumption of a triacylglycerol control oil. Food Chem Toxicol 2004;42:1419–1429.
Soni MG, Kimura H, Burdock GA. Chronic study of diacylglycerol oil in rats. Food Chem Toxicol 2001;39:317–329.
Kasamatsu T, Ogura R, Ikeda N, et al. Genotoxicity studies on dietary diacylglycerol (DAG) oil. Food Chem Toxicol 2005;43:253–260.
Chengelis CP, Kirkpatrick JB, Marit GB, et al. A chronic dietary toxicity study of DAG (diacylglycerol) in Beagle dogs. Food Chem Toxicol 2006;44:81–97.
Wolever TMS. The glycemic index: methodology and clinical implications. Am J Clin Nutr 1991;54:846–854.
Brand JC, Nicholson PL, Thorburn AW, et al. Food processing and the glycemic index. Am J Clin Nutr 1985;42:1192–1196.
Jenkins DJ, Ghafari H, Wolever TM, et al. Relationship between rate of digestion of foods and post-prandial glycaemia. Diabetologia 1982;22:450–455.
Wolever TM. Relationship between dietary fiber content and composition in foods and the glycemic index. Am J Clin Nutr 1990;51:72–75.
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