Cover Journal of the American Veterinary Medical Association
Journal of the American Veterinary Medical Association
ISSN:
0003-1488
Publication Date:
15 Nov 2009
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Editorial Type:
Pathology in Practice

Pathology In Practice

Pamela J. Mouser DVM, DACVP1, José A. Ramos-Vara DVM2, Ramesh Vemulapalli MVSc, PhD3, and J. Catharine Scott-Moncrieff Vet MB, DACVIM4
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  • 1 Animal Disease Diagnostic Laboratory and the Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
  • | 2 Animal Disease Diagnostic Laboratory and the Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
  • | 3 Animal Disease Diagnostic Laboratory and the Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
  • | 4 Animal Disease Diagnostic Laboratory and the Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
DOI:
https://doi.org/10.2460/javma.235.10.1153
Volume/Issue:
Volume 235: Issue 10
Online Publication Date:
15 Nov 2009
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History

A 6.5-year-old 10-kg (22-lb) castrated male mixed-breed dog was referred for evaluation of persistent lethargy, vomiting, thrombocytopenia, anemia, and pyrexia of approximately 1 month's duration. Treatments administered prior to referral included oral administration of the antiemetic metoclopramide hydrochloride (0.5 mg/kg [0.23 mg/lb], q 12 h) and amoxicillin (25 mg/kg [11.4 mg/lb], q 12 h) for 1 week, followed by oral administration of prednisone (2 mg/kg [0.9 mg/lb], q 12 h) for 1 week. Intermittent seizures began during treatment with prednisone; the frequency of drug administration was decreased (2 mg/kg, q 24 h) 3 days prior to referral.

 Clinical and
History

A 6.5-year-old 10-kg (22-lb) castrated male mixed-breed dog was referred for evaluation of persistent lethargy, vomiting, thrombocytopenia, anemia, and pyrexia of approximately 1 month's duration. Treatments administered prior to referral included oral administration of the antiemetic metoclopramide hydrochloride (0.5 mg/kg [0.23 mg/lb], q 12 h) and amoxicillin (25 mg/kg [11.4 mg/lb], q 12 h) for 1 week, followed by oral administration of prednisone (2 mg/kg [0.9 mg/lb], q 12 h) for 1 week. Intermittent seizures began during treatment with prednisone; the frequency of drug administration was decreased (2 mg/kg, q 24 h) 3 days prior to referral.

 Clinical and

Contributor Notes

Dr. Mouser's present address is Angell Animal Medical Center, 350 S Huntington Ave, Boston, MA 02130.

Presented at the 27th annual meeting of the Midwest Association of Veterinary Pathologists, College Corner, Ohio, August 2008.

Address correspondence to Dr. Mouser (pmouser@mspca.org).