Cover Journal of the American Veterinary Medical Association
Journal of the American Veterinary Medical Association
ISSN:
0003-1488
Publication Date:
15 Sep 2006
  • 1

    Sepesy LM, Center SA, Randolph JF, et al. Vacuolar hepatopathy in dogs: 336 cases (1993–2005). J Am Vet Med Assoc 2006;229:246–252.

  • 1

    Rogers WA, Ruebner BH. A retrospective study of probable glucocorticoidinduced hepatopathy in dogs. J Am Vet Med Assoc 1977;170:603–606.

    • Search Google Scholar
    • Export Citation
  • 1

    Burns MK. Teaching hospitals short on specialists. J Am Vet Med Assoc 2006;229:339–340.

  • 2

    Veterinary Information Network Inc. Available at: www.vin.com/Members/BoardsMain/Boards.plx?Read=2&Id=4*135*514383. Accessed Aug 8, 2006.

    • Search Google Scholar
    • Export Citation
  • 1

    Baggot SM. Veterinarians as advocates for animal rights. J Am Vet Med Assoc 2006;229:350–352.

  • 1

    Arnot C, Gauldin C. AVMA Exec Board shoots down partnership with animal welfare group. Feedstuffs 2006;July 3:12.

Advertisement

Editorial Type:
Views

Letter to the Editor

DOI:
https://doi.org/10.2460/javma.229.6.918
Volume/Issue:
Volume 229: Issue 6
Online Publication Date:
15 Sep 2006
Restricted access
Reprints and Permissions Purchase Article
Questions value of vacuolar hepatopathy study

In the July 15, 2006, issue of the JAVMA, Sepesy et al1 provide empiric evidence that dogs with vacuolar hepatopathy (VH), referring to morphologic alterations in hepatocytes subjected to glucocorticoids, often have a variety of other disorders that do not include “overt” glucocorticoid drug exposure or hyperadrenocorticism (HAC). The clinical implication is that detection of glycogenosis and ballooning of hepatocytes (ie, VH) is not as specific for glucocorticosteroid exposure or HAC as generally perceived.

I contend that this retrospective evaluation does not contribute valid data to clarifying specificity of VH
Questions value of vacuolar hepatopathy study

In the July 15, 2006, issue of the JAVMA, Sepesy et al1 provide empiric evidence that dogs with vacuolar hepatopathy (VH), referring to morphologic alterations in hepatocytes subjected to glucocorticoids, often have a variety of other disorders that do not include “overt” glucocorticoid drug exposure or hyperadrenocorticism (HAC). The clinical implication is that detection of glycogenosis and ballooning of hepatocytes (ie, VH) is not as specific for glucocorticosteroid exposure or HAC as generally perceived.

I contend that this retrospective evaluation does not contribute valid data to clarifying specificity of VH