• 1

    Salati LM, Goodridge AG. Fatty acid synthesis in eukaryotes. In:Vance DE, Vance JE, ed.Biochemistry of lipids, lipoproteins and membranes. Amsterdam: Elsevier, 1996;101–128.

    • Search Google Scholar
    • Export Citation
  • 2

    Cook HW. Fatty acid desaturation and chain elongation in eukaryotes. In:Vance DE, Vance JE, ed.Biochemistry of lipids, lipoproteins and membranes. Amsterdam: Elsevier, 1996;129–152.

    • Search Google Scholar
    • Export Citation
  • 3

    Bauer JE. Fatty acid metabolism in domestic cats (Felis catus) and cheetahs (Acononyx jubatus), in Proceedings. Nutr Soc 1997;56:1013–1024.

    • Search Google Scholar
    • Export Citation
  • 4

    Rodriguez A, Sarda P, Boulot P, et al. Differential effects of n-ethyl maleimine on Δ-6 desaturase activity in human fetal liver toward fatty acids of the n-6 and n-3 series. Lipids 1999;34:23–30.

    • Search Google Scholar
    • Export Citation
  • 5

    Rivers JPW, Sinclair AJ, Crawford MA. Inability of the cat to desaturate essential fatty acids. Nature 1975;258:171–173.

  • 6

    Pawlosky R, Barnes A & Salem N Jr. Essential fatty acid metabolism in the feline; relationship between liver and brain production of long-chain polyunsaturated fatty acids. J Lipid Res 1994;35:2032–2040.

    • Search Google Scholar
    • Export Citation
  • 7

    Heinemann KM, Waldron MK, Bigley KE, et al. Long chain (n-3) polyunsaturated fatty acids are more efficient than α-linolenic acid in improving electroretinogram responses of puppies exposed during gestation, lactation, and weaning. J Nutr 2005;135:1960–1966.

    • Search Google Scholar
    • Export Citation
  • 8

    Carlson SE. Are n-3 polyunsaturated fatty acids essential for growth and development? In:Nelson GJ, ed.Health effects of dietary fatty acids. Champaign, Ill: American Oil Chemists Society, 1990;42–50.

    • Search Google Scholar
    • Export Citation
  • 9

    Simopoulos AP. Omega-3 fatty acids in health and disease and in growth and development. Am J Clin Nutr 1991;54:438–463.

  • 10

    Conner WE, Neuringer M, Reisbeck S. Essential fatty acids: the importance of n-3 fatty acids in the retina and brain. Nutr Rev 1992;50:21–29.

    • Search Google Scholar
    • Export Citation
  • 11

    Uauy R, Peirano P, Hoffman D, et al. Role of essential fatty acids in the function of the developing nervous system. Lipids 1996;31:S167–S176.

    • Search Google Scholar
    • Export Citation
  • 12

    Pawlosky RJ, Denkins Y, Ward G, et al. Retinal and brain accretion of long-chain polyunsaturated fatty acids in developing felines: the effects of corn-based maternal diets. Am J Clin Nutr 1997;65:465–472.

    • Search Google Scholar
    • Export Citation
  • 13

    Waldron MK, Spencer AS, Bauer JE. Role of long-chain polyunsaturated n-3 fatty acids in the development of the nervous system of dogs and cats. J Am Vet Med Assoc 1998;213:619–622.

    • Search Google Scholar
    • Export Citation
  • 14

    Rivers JPW, Frankel TL. Fat in the diet of dogs and cats. In:Anderson RS, ed.Nutrition of the dog and cat. Oxford, UK: Pergamon Press, 1980;67–99.

    • Search Google Scholar
    • Export Citation
  • 15

    Sinclair AJ, McLean JG, Monger EA. Metabolism of linoleic acid in the cat. Lipids 1979;14:932–936.

  • 16

    Sinclair AJ, Slattery WJ, McLean JG, et al. Essential fatty acid deficiency and evidence for arachidonate synthesis in the cat. Br J Nutr 1981;46:93–96.

    • Search Google Scholar
    • Export Citation
  • 17

    McLean JG, Monger EA. Factors determining the essential fatty acid requirements of the cat. In:Burger IH, Rivers JPW, ed.Nutrition of the dog and cat. Waltham symposium number 7. Cambridge, UK: Cambridge University Press, 1989;349–342.

    • Search Google Scholar
    • Export Citation
  • 18

    Macdonald ML, Rogers QR, Morris JG, et al. Effects of linoleate and arachidonate deficiencies on reproduction and spermatogenesis in the cat. J Nutr 1984;114:719–726.

    • Search Google Scholar
    • Export Citation
  • 19

    Pawlosky RJ & Salem N. Jr. Is dietary arachidonic acid necessary for reproduction? J Nutr 1996;126:1081S–1085S.

  • 20

    Morris JG. Do cats need arachidonic acid in the diet for reproduction? J Anim Physiol Anim Nutr (Berl) 2004;88:131–137.

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Metabolic basis for the essential nature of fatty acids and the unique dietary fatty acid requirements of cats

John E. Bauer DMV, PhD, DACVN1
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  • 1 Comparative Nutrition Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4474.