Survival times in dogs with right atrial hemangiosarcoma treated by means of surgical resection with or without adjuvant chemotherapy: 23 cases (1986–2000)

Chick Weisse Section of Small Animal Surgery, Department of Clinical Studies—Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6010.

Search for other papers by Chick Weisse in
Current site
Google Scholar
PubMed
Close
 VMD
,
Nancy Soares Hamilton Animal Care, 6110 Hamilton Blvd, Wescosville, PA 18106.

Search for other papers by Nancy Soares in
Current site
Google Scholar
PubMed
Close
 VMD
,
Matthew W. Beal Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824-1314.

Search for other papers by Matthew W. Beal in
Current site
Google Scholar
PubMed
Close
 DVM
,
Michele A. Steffey Section of Small Animal Surgery, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.

Search for other papers by Michele A. Steffey in
Current site
Google Scholar
PubMed
Close
 DVM
,
Kenneth J. Drobatz Section of Critical Care, Department of Clinical Studies—Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6010.

Search for other papers by Kenneth J. Drobatz in
Current site
Google Scholar
PubMed
Close
 DVM
, and
Carolyn J. Henry Section of Oncology, Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211.

Search for other papers by Carolyn J. Henry in
Current site
Google Scholar
PubMed
Close
 DVM

Abstract

Objective—To determine survival times in dogs with right atrial hemangiosarcoma treated by means of pericardectomy and tumor resection, with or without adjuvant chemotherapy, and identify complications associated with treatment.

Design—Retrospective study.

Animals—23 dogs.

Procedure—Dogs were included only if the diagnosis was confirmed histologically.

Results—The most common initial complaints included acute collapse (8 [35%] dogs), anorexia or inappetence (8 [35%]), and lethargy (8 [35%]). The most common physical examination abnormalities included muffled heart sounds (12 [52%] dogs), tachycardia (7 [30%]), and weak pulses (7 [30%]). Postoperative complications developed in 12 (52%) dogs; however, most complications were minor. Twenty (87%) dogs were discharged from the hospital. Survival time was significantly longer in the 8 dogs that received adjuvant chemotherapy (mean, 164 days; median, 175 days) than in the 15 dogs that did not receive chemotherapy (mean, 46 days; median, 42 days). Dogs that received chemotherapy were significantly younger and had significantly lower WBC counts than did dogs that did not receive chemotherapy.

Conclusions and Clinical Relevance—Results suggested that in dogs with right atrial hemangiosarcoma, surgical resection of the tumor was associated with a low complication rate and complications that did arise typically were minor. In addition, use of adjuvant chemotherapy following resection was associated with significantly longer survival times, compared with resection alone. (J Am Vet Med Assoc 2005;226:575–579)

Abstract

Objective—To determine survival times in dogs with right atrial hemangiosarcoma treated by means of pericardectomy and tumor resection, with or without adjuvant chemotherapy, and identify complications associated with treatment.

Design—Retrospective study.

Animals—23 dogs.

Procedure—Dogs were included only if the diagnosis was confirmed histologically.

Results—The most common initial complaints included acute collapse (8 [35%] dogs), anorexia or inappetence (8 [35%]), and lethargy (8 [35%]). The most common physical examination abnormalities included muffled heart sounds (12 [52%] dogs), tachycardia (7 [30%]), and weak pulses (7 [30%]). Postoperative complications developed in 12 (52%) dogs; however, most complications were minor. Twenty (87%) dogs were discharged from the hospital. Survival time was significantly longer in the 8 dogs that received adjuvant chemotherapy (mean, 164 days; median, 175 days) than in the 15 dogs that did not receive chemotherapy (mean, 46 days; median, 42 days). Dogs that received chemotherapy were significantly younger and had significantly lower WBC counts than did dogs that did not receive chemotherapy.

Conclusions and Clinical Relevance—Results suggested that in dogs with right atrial hemangiosarcoma, surgical resection of the tumor was associated with a low complication rate and complications that did arise typically were minor. In addition, use of adjuvant chemotherapy following resection was associated with significantly longer survival times, compared with resection alone. (J Am Vet Med Assoc 2005;226:575–579)

Advertisement