Effect of an external nasal dilator strip on cytologic characteristics of bronchoalveolar lavage fluid in Thoroughbred racehorses

Sandra C. Valdez Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616.

Search for other papers by Sandra C. Valdez in
Current site
Google Scholar
PubMed
Close
 MVZ
,
Jorge E. Nieto Departments of Surgery and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616.

Search for other papers by Jorge E. Nieto in
Current site
Google Scholar
PubMed
Close
 MVZ
,
Sharon J. Spier Departments of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616.

Search for other papers by Sharon J. Spier in
Current site
Google Scholar
PubMed
Close
 DVM, PhD
,
Sean D. Owens Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616.

Search for other papers by Sean D. Owens in
Current site
Google Scholar
PubMed
Close
 DVM
,
Pablo Beldomenico Departments of Surgery and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616.
Current address: Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, Santa Fe, Argentina.

Search for other papers by Pablo Beldomenico in
Current site
Google Scholar
PubMed
Close
 MV, MPVM
, and
Jack R. Snyder Departments of Surgery and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616.

Search for other papers by Jack R. Snyder in
Current site
Google Scholar
PubMed
Close
 DVM, PhD

Abstract

Objective—To determine the effects of an external nasal dilator strip on cytologic characteristics of bronchoalveolar lavage (BAL) fluid in racing Thoroughbreds.

Design—Clinical trial.

Animals—23 Thoroughbred racehorses in active training.

Procedure—Each horse raced on 2 occasions: once while wearing an external nasal dilator strip and once while not. Bronchoalveolar lavage was performed 12 to 18 hours after each race, and BAL fluid was analyzed for RBC and leukocyte counts and hemosiderin content.

Results—Mean ± SEM count of RBCs in BAL fluid when horses raced without the nasal dilator strip (84.6 ± 27.5 cells/µL) was not significantly different from count when they raced with it (41.7 ± 12.2 cells/µL). Horses were grouped as having mild or severe bleeding on the basis of RBC count in BAL fluid after horses raced without the nasal dilator strip. Mean count when horses with severe bleeding raced without the nasal dilator strip (271.0 ± 63.7 cells/µL) was significantly higher than mean count when these horses raced with the strip (93.8 ± 37.6 cells/µL). Mean count of lymphocytes in BAL fluid was significantly lower after horses raced with the external nasal dilator strip.

Conclusions and Clinical Relevance—Results suggest that use of an external nasal dilator strip in Thoroughbred racehorses may decrease pulmonary bleeding, particularly in horses with severe exerciseinduced pulmonary hemorrhage. ( J Am Vet Med Assoc 2004;224:558–561)

Abstract

Objective—To determine the effects of an external nasal dilator strip on cytologic characteristics of bronchoalveolar lavage (BAL) fluid in racing Thoroughbreds.

Design—Clinical trial.

Animals—23 Thoroughbred racehorses in active training.

Procedure—Each horse raced on 2 occasions: once while wearing an external nasal dilator strip and once while not. Bronchoalveolar lavage was performed 12 to 18 hours after each race, and BAL fluid was analyzed for RBC and leukocyte counts and hemosiderin content.

Results—Mean ± SEM count of RBCs in BAL fluid when horses raced without the nasal dilator strip (84.6 ± 27.5 cells/µL) was not significantly different from count when they raced with it (41.7 ± 12.2 cells/µL). Horses were grouped as having mild or severe bleeding on the basis of RBC count in BAL fluid after horses raced without the nasal dilator strip. Mean count when horses with severe bleeding raced without the nasal dilator strip (271.0 ± 63.7 cells/µL) was significantly higher than mean count when these horses raced with the strip (93.8 ± 37.6 cells/µL). Mean count of lymphocytes in BAL fluid was significantly lower after horses raced with the external nasal dilator strip.

Conclusions and Clinical Relevance—Results suggest that use of an external nasal dilator strip in Thoroughbred racehorses may decrease pulmonary bleeding, particularly in horses with severe exerciseinduced pulmonary hemorrhage. ( J Am Vet Med Assoc 2004;224:558–561)

All Time Past Year Past 30 Days
Abstract Views 98 0 0
Full Text Views 760 583 14
PDF Downloads 119 66 3
Advertisement