Objective—To evaluate the clinical application of a
catheter-delivered, self-expanding occluding stent for
closure of patent ductus arteriosus (PDA) in dogs.
Animals—23 client-owned dogs weighing at least 3
kg (6.6 lb).
Procedure—Dogs were evaluated by physical examination,
electrocardiography, thoracic radiography, and
2-dimensional, M-mode, spectral and color-flow
Doppler echocardiography to confirm the diagnosis
and obtain baseline measures. Shunt severity and
ductal size and anatomy were established by means
of angiography. With fluoroscopic guidance, the
occluding stent, attached to a delivery cable, was
maneuvered though the right side of the heart into
the ductus via a prepositioned introducer sheath.
After angiographic verification of appropriate stent
placement, the delivery cable was detached, and the
introducer sheath was withdrawn. Closure of the PDA
was evaluated by means of angiography 15 minutes
after stent deployment and by echocardiography 1
and 3 months after the procedure.
Results—There were no operative deaths. There
were 2 deployment failures, both attributable to avoidable
operator errors. Angiography performed after
stent deployment indicated PDA closure in 13 of 20
(65%) dogs. There were 2 postoperative deaths in
dogs with heart failure; both deaths were thought to
be unrelated to use of the occluding stent. Complete
PDA closure, determined by Doppler color-flow
echocardiography, was evident in 17 of 19 dogs within
3 months and in 1 additional dog within 1 year of
stent deployment, resulting in closure in 18 of 19
dogs completing the study protocol.
Conclusions and Clinical Relevance—Results suggest
that a catheter-delivered occluding stent can be
used successfully to close PDAs in dogs. (J Am Vet
Med Assoc 2003;223:999–1005)