Objective—To evaluate a continuous glucose monitoring
system (CGMS) for use in dogs, cats, and horses.
Design—Prospective clinical study.
Animals—7 horses, 3 cats, and 4 dogs that were clinically
normal and 1 horse, 2 cats, and 3 dogs with diabetes
Procedure—Interstitial glucose concentrations were
monitored and recorded every 5 minutes by use of a
CGMS. Interstitial glucose concentrations were compared
with whole blood glucose concentrations as
determined by a point-of-care glucose meter.
Interstitial glucose concentrations were also monitored
in 2 clinically normal horses after oral and IV
administration of glucose.
Results—There was a positive correlation between
interstitial and whole blood glucose concentrations
for clinically normal dogs, cats, and horses and those
with diabetes mellitus. Events such as feeding, glucose
or insulin administration, restraint, and transport
to the clinic were recorded by the owner or clinician
and could be identified on the graph and associated
with time of occurrence.
Conclusions and Clinical Relevance—Our data indicate
that use of CGMS is valid for dogs, cats, and
horses. This system alleviated the need for multiple
blood samples and the stress associated with
obtaining those samples. Because hospitalization
was not required, information obtained from the
CGMS provided a more accurate assessment of the
animal's glucose concentrations for an extended
period, compared with measurement of blood glucose
concentrations. Use of the CGMS will promote
the diagnostic and research potential of serial glucose
monitoring. (J Am Vet Med Assoc 2003;223: