Objective—To describe diseases, prognosis, and clinical
outcomes associated with extreme neutrophilic
leukocytosis in cats.
Animals—104 cats with extreme neutrophilic leukocytosis.
Procedure—Medical records from 1991 to 1999 were
examined to identify cats that had ≥ 50,000 WBC/µl
with ≥ 50% neutrophils. Signalment, absolute and differential
WBC counts, rectal temperature, clinical or
pathologic diagnosis, duration and cost of hospitalization,
and survival time were reviewed.
Results—Mean age of cats was 8.3 years, mean
WBC count was 73,055 cells/µl, and mean absolute
neutrophil count was 59,046 cells/µl. Mean duration
of hospitalization was 5.9 days, and mean cost of hospitalization
was $2,010. Twenty-nine (28%) cats were
febrile, and 63 (61%) cats died. Overall median survival
time was 30 days. Cats with neoplasia were
nearly 14 times as likely to die unexpectedly as cats
with other diseases.
Conclusions and Clinical Relevance—Extreme neutrophilic
leukocytosis was associated with a high mortality
rate. The prognostic importance of extreme neutrophilic
leukocytosis should not be overlooked. Cats and
dogs have similar diseases, mortality rates, and treatment
costs associated with extreme neutrophilic leukocytosis.
(J Am Vet Med Assoc 2001;218:736–739)