Cover American Journal of Veterinary Research
American Journal of Veterinary Research
ISSN:
0002-9645
Publication Date:
01 Sep 2020

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Editorial Type:
Surgery

Feasibility and efficacy of ultrasonographic and laparoscopic guidance for microwave ablation of clinically normal canine ovaries

Valentine D. Verpaalen DVM, MS1, J. Brad Case DVM, MS1, Michael J. Dark DVM, PHD1, S. Joel Cardenas-Goicoechea MD2, Matt D. Winter DVM1, Sarah E. Boston DVM, DVSC3, Fernando Garcia-Pereira DVM, MS1, Alice S. Rhoton-Vlasak MD2, and Beau B. Toskich MD4
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  • 1 1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Gainesville, FL 32608.
  • | 2 2Department of Obstetrics and Gynecology, College of Medicine, University of Florida, Gainesville, FL 32608.
  • | 3 3VCA 404 Veterinary Emergency and Referral Hospital, Newmarket, ON L3Y 0B3, Canada.
  • | 4 4Department of Radiology, Mayo Clinic, Jacksonville, FL 32224.
DOI:
https://doi.org/10.2460/ajvr.81.9.747
Volume/Issue:
Volume 81: Issue 9
Online Publication Date:
01 Sep 2020
Restricted access
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Abstract

OBJECTIVE

To determine the optimal energy profile for and to assess the feasibility and efficacy of ultrasonographic and laparoscopic guidance for microwave ablation (MWA) of clinically normal canine ovaries.

SAMPLE

44 extirpated ovaries from 22 healthy dogs.

PROCEDURES

In the first of 2 trials, 13 dogs underwent oophorectomy by routine laparotomy. Extirpated ovaries underwent MWA at 45 W for 60 (n = 11) or 90 (12) seconds; 3 ovaries did not undergo MWA and served as histologic controls. Ovaries were histologically evaluated for cell viability. Ovaries without viable cells were categorized as completely ablated. Histologic results were used to identify the optimal MWA protocol for use in the subsequent trial. In the second trial, the ovaries of 9 dogs underwent MWA at 45 W for 90 seconds in situ. Ultrasonographic guidance for MWA was deemed unfeasible after evaluation of 1 ovary. The remaining 17 ovaries underwent MWA with laparoscopic guidance, after which routine laparoscopic oophorectomy was performed. Completeness of ablation was histologically assessed for all ovaries.

RESULTS

2 ovaries were excluded from the trial 1 analysis because of equivocal cell viability. Six of 11 ovaries and 10 of 10 ovaries that underwent MWA for 60 and 90 seconds, respectively, were completely ablated. In trial 2, laparoscopic-guided MWA resulted in complete ablation for 12 of 17 ovaries. Dissection of the ovarian bursa for MWA probe placement facilitated complete ablation.

CONCLUSIONS AND CLINICAL RELEVANCE

Laparoscopic-guided MWA at 45 W for 90 seconds was feasible, safe, and effective for complete ablation of clinically normal ovaries in dogs.

Contributor Notes

Address correspondence to Dr. Case (caseb@ufl.edu).