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1. Goggs R, Chan DL, Benigni L, et al. Comparison of computed tomography pulmonary angiography and point-of-care tests for pulmonary thromboembolism diagnosis in dogs. J Small Anim Pract 2014;55:190–197.
-
2. Wittram C, Maher MM, Yoo AJ, et al. CT angiography of pulmonary embolism: diagnostic criteria and causes of misdiagnosis. Radiographics 2004;24:1219–1238.
-
3. Ngwenyama TR, Herring JM, O'Brien M, et al. Contrast-enhanced multidetector computed tomography to diagnose pulmonary thromboembolism in an awake dog with pyothorax. J Vet Emerg Crit Care (San Antonio) 2014;24:731–738.
-
4. Schoepf UJ, Costello P. CT angiography for diagnosis of pulmonary embolism: state of the art. Radiology 2004;230:329–337.
-
5. Goggs R, Benigni L, Fuentes VL, et al. Pulmonary thromboembolism. J Vet Emerg Crit Care (San Antonio) 2009;19:30–52.
-
6. Drees R, Francois CJ, Saunders JH. Invited review—computed tomographic angiography (CTA) of the thoracic cardiovascular system in companion animals. Vet Radiol Ultrasound 2014;55:229–240.
-
7. Habing A, Coelho JC, Nelson N, et al. Pulmonary angiography using 16 slice multidetector computed tomography in normal dogs. Vet Radiol Ultrasound 2011;52:173–178.
-
8. Drees R, Frydrychowicz A, Keuler NS, et al. Pulmonary angiography with 64-multidetector-row computed tomography in normal dogs. Vet Radiol Ultrasound 2011;52:362–367.
-
9. Makara M, Dennler M, Kühn K, et al. Effect of contrast medium injection duration on peak enhancement and time to peak enhancement of canine pulmonary arteries. Vet Radiol Ultrasound 2011;52:605–610.
-
10. Behrendt FF, Jost G, Pietsch H, et al. Computed tomography angiography: the effect of different chaser flow rates, volumes, and fluids on contrast enhancement. Invest Radiol 2011;46:271–276.
-
11. Raczeck P, Minko P, Graeber S, et al. Influence of respiratory position on contrast attenuation in pulmonary CT angiography: a prospective randomized clinical trial. AJR Am J Roentgenol 2016;206:481–486.
-
12. Wittram C, Yoo AJ. Transient interruption of contrast on CT pulmonary angiography: proof of mechanism. J Thorac Imaging 2007;22:125–129.
-
13. Renne J, Falck CV, Ringe KI, et al. CT angiography for pulmonary embolism detection: the effect of breathing on pulmonary artery enhancement using a 64-row detector system. Acta Radiol 2014;55:932–937.
-
14. Kuzo RS, Pooley RA, Crook JE, et al. Measurement of caval blood flow with MRI during respiratory maneuvers: implications for vascular contrast opacification on pulmonary CT angiographic studies. AJR Am J Roentgenol 2007;188:839–842.
-
15. Mortimer AM, Singh RK, Hughes J, et al. Use of expiratory CT pulmonary angiography to reduce inspiration and breath-hold associated artefact: contrast dynamics and implications for scan protocol. Clin Radiol 2011;66:1159–1166.
-
16. Powell FL, Wagner PD, West JB. Ventilation, blood flow, and gas exchange. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's textbook of respiratory medicine. 6th ed. Philadelphia: WB Saunders Co, 2016;44–75.
-
17. Garcia JGN. Pulmonary circulation and regulation of fluid balance. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's textbook of respiratory medicine. 6th ed. Philadelphia: WB Saunders Co, 2016;92–110.
-
18. Patel S, Kazerooni EA, Cascade PN. Pulmonary embolism: optimization of small pulmonary artery visualization at multi-detector row CT. Radiology 2003;227:455–460.
-
19. Miller WT Jr, Marinari LA, Barbosa E Jr, et al. Small pulmonary artery defects are not reliable indicators of pulmonary embolism. Ann Am Thorac Soc 2015;12:1022–1029.
-
20. Bae KT. Intravenous contrast medium administration and scan timing at CT: considerations and approaches. Radiology 2010;256:32–61.
-
21. Guarracino A, Lacitignola L, Auriemma E, et al. Which airway pressure should be applied during breath-hold in dogs undergoing thoracic computed tomography? Vet Radiol Ultrasound 2016;57:475–481.
-
22. Scharf SM, Caldini P, Ingram RH Jr. Cardiovascular effects of increasing airway pressure in the dog. Am J Physiol 1977;232:H35–H43.
-
23. Sakai S, Yabuuchi H, Chishaki A, et al. Effect of cardiac function on aortic peak time and peak enhancement during coronary CT angiography. Eur J Radiol 2010;75:173–177.
-
24. Bae KT, Heiken JP, Brink JA. Aortic and hepatic contrast medium enhancement at CT. Part II. Effect of reduced cardiac output in a porcine model. Radiology 1998;207:657–662.
-
25. Scott JC, Finkelstein LJ, Croll MN. Effects of hypoxemia on coronary blood flow and cardiac output in normal and hypothyroid dogs. Am J Cardiol 1962;10:840–845.
-
26. Pinsky MR. Recent advances in the clinical application of heart-lung interactions. Curr Opin Crit Care 2002;8:26–31.
-
27. Fessler HE, Brower RG, Wise RA, et al. Effects of positive end-expiratory pressure on the canine venous return curve. Am Rev Respir Dis 1992;146:4–10.
-
28. Berger D, Moller PW, Weber A, et al. Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. Am J Physiol Heart Circ Physiol 2016;311:H794–H806.
-
29. Moore NR, Scott JP, Flower CD, et al. The relationship between pulmonary artery pressure and pulmonary artery diameter in pulmonary hypertension. Clin Radiol 1988;39:486–489.
-
30. Kallas HJ, Domino KB, Glenny RW, et al. Pulmonary blood flow redistribution with low levels of positive end-expiratory pressure. Anesthesiology 1998;88:1291–1299.
-
31. Levitzky MG. Chapter 4. Blood flow to the lung. In: Levitzky MG, ed. Pulmonary physiology. 8th ed. New York: The McGraw-Hill Co, 2013;97–103.
-
32. Tidwell SA, Graham JP, Peck JN, et al. Incidence of pulmonary embolism after non-cemented total hip arthroplasty in eleven dogs: computed tomographic pulmonary angiography and pulmonary perfusion scintigraphy. Vet Surg 2007;36:37–42.
-
33. Wittram C. How I do it: CT pulmonary angiography. AJR Am J Roentgenol 2007;188:1255–1261.
-
34. Hunsaker AR, Oliva IB, Cai T, et al. Contrast opacification using a reduced volume of iodinated contrast material and low peak kilovoltage in pulmonary CT angiography: objective and subjective evaluation. AJR Am J Roentgenol 2010;195:W118–W124.
-
35. Rodrigues JC, Mathias H, Negus IS, et al. Intravenous contrast medium administration at 128 multidetector row CT pulmonary angiography: bolus tracking versus test bolus and the implications for diagnostic quality and effective dose. Clin Radiol 2012;67:1053–1060.
-
36. Hopper K, Powell LL. Basics of mechanical ventilation for dogs and cats. Vet Clin North Am Small Anim Pract 2013;43:955–969.
-
37. MacDonnell KF, Lefemine AA, Moon HS, et al. Comparative hemodynamic consequences of inflation hold, PEEP, and interrupted PEEP: an experimental study in normal dogs. Ann Thorac Surg 1975;19:552–560.
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Effects of airway pressure on contrast enhancement and diameter of the pulmonary artery in healthy dogs as determined by use of computed tomography angiography
Abstract
OBJECTIVE
To evaluate effects of airway pressure on contrast enhancement and diameter of the pulmonary artery and determine the optimal airway pressure for pulmonary CT angiography in dogs.
ANIMALS
8 healthy Beagles.
PROCEDURES
Thoracic CT was performed at end-expiration (0 cm H2O) and 2 positive-pressure end-inspirations (10 and 20 cm H2O). Attenuation curves of enhancement for the sinus of the pulmonary trunk artery were obtained by use of a bolus technique. Contrast medium (300 mg of I/kg) was administered IV, and CT imaging began at the time of peak enhancement. At each pressure, time to peak enhancement, ratio of blood flow from the caudal vena cava to the right side of the heart (KCdVC), and enhancement characteristics and diameter changes of the pulmonary artery were evaluated.
RESULTS
All dogs had a significant delay for time to peak enhancement in the sinus of the pulmonary trunk artery as airway pressure increased. The KCdVC progressively increased as airway pressure increased, and there was low contrast enhancement and increased pulmonary artery filling defects at 20 cm H2O. All pulmonary arteries had marked increases in diameter as pressure increased. Arterial distensibility in the gravity-dependent cranial lung region was greater than that in the gravity-independent caudal lung region at the 2 positive-pressure end-inspirations.
CONCLUSIONS AND CLINICAL RELEVANCE
Airway pressure affected time to peak enhancement, KCdVC, contrast enhancement, and pulmonary artery diameter. Results suggested that 10 cm H2O could be an optimal pressure for evaluation of the pulmonary artery of dogs by use of CT angiography. (Am J Vet Res 2019;80;756–763)
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