The effects of lidocaine or a lidocaine-bupivacaine mixture administered into the infraorbital canal in dogs

Peter J. Pascoe Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616.

Search for other papers by Peter J. Pascoe in
Current site
Google Scholar
PubMed
Close
 BVSC

Abstract

OBJECTIVE To determine the onset, duration, and extent of regional nerve blocks performed by administration of lidocaine or lidocaine-bupivacaine into the infraorbital canal in dogs.

ANIMALS 6 healthy hound-type dogs.

PROCEDURES Under general anesthesia, stimulating needles were inserted into the gingiva dorsolateral to both maxillary canine (MC) teeth and the maxillary fourth premolar (MPM4) and second molar (MM2) teeth on the treatment side. A reflex-evoked muscle potential (REMP) was recorded from the digastricus muscle after noxious electrical stimulation at each site. After baseline measurements, 1 mL of 2% lidocaine solution or a 2% lidocaine-0.5% bupivacaine mixture (0.5 mL each) was injected into the infraorbital canal (at approx two-thirds of the canal length measured rostrocaudally). The REMPs were recorded for up to 7 hours. The REMP data for the contralateral (untreated control) canine tooth were used to normalize results for all stimulation sites.

RESULTS With both treatments, nerve block for MC teeth on the treated side was achieved by 5 (n = 5 dogs) or 10 (1) minutes after injection, but nerve block for ipsilateral MPM4 and MM2 teeth was successful for only 3 dogs and 1 dog, respectively. Mean duration of nerve blocks for MC teeth was 120 and 277 minutes following injection of lidocaine and lidocaine-bupivacaine, respectively.

CONCLUSIONS AND CLINICAL RELEVANCE Local anesthesia, as performed in this study, successfully blocked innervation of MC teeth, but results for MPM4 and MM2 teeth were inconsistent. This specific technique should not be used during tooth extractions caudal to the MC teeth.

Abstract

OBJECTIVE To determine the onset, duration, and extent of regional nerve blocks performed by administration of lidocaine or lidocaine-bupivacaine into the infraorbital canal in dogs.

ANIMALS 6 healthy hound-type dogs.

PROCEDURES Under general anesthesia, stimulating needles were inserted into the gingiva dorsolateral to both maxillary canine (MC) teeth and the maxillary fourth premolar (MPM4) and second molar (MM2) teeth on the treatment side. A reflex-evoked muscle potential (REMP) was recorded from the digastricus muscle after noxious electrical stimulation at each site. After baseline measurements, 1 mL of 2% lidocaine solution or a 2% lidocaine-0.5% bupivacaine mixture (0.5 mL each) was injected into the infraorbital canal (at approx two-thirds of the canal length measured rostrocaudally). The REMPs were recorded for up to 7 hours. The REMP data for the contralateral (untreated control) canine tooth were used to normalize results for all stimulation sites.

RESULTS With both treatments, nerve block for MC teeth on the treated side was achieved by 5 (n = 5 dogs) or 10 (1) minutes after injection, but nerve block for ipsilateral MPM4 and MM2 teeth was successful for only 3 dogs and 1 dog, respectively. Mean duration of nerve blocks for MC teeth was 120 and 277 minutes following injection of lidocaine and lidocaine-bupivacaine, respectively.

CONCLUSIONS AND CLINICAL RELEVANCE Local anesthesia, as performed in this study, successfully blocked innervation of MC teeth, but results for MPM4 and MM2 teeth were inconsistent. This specific technique should not be used during tooth extractions caudal to the MC teeth.

Contributor Notes

Address correspondence to Dr. Pascoe (pjpascoe@ucdavis.edu).
  • 1. Rooney BA, Crown ED, Hulsebosch CE, et al. Preemptive analgesia with lidocaine prevents Failed Back Surgery Syndrome. Exp Neurol 2007; 204: 589596.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2. Campoy L, Martin-Flores M, Ludders JW, et al. Comparison of bupivacaine femoral and sciatic nerve block versus bupivacaine and morphine epidural for stifle surgery in dogs. Vet Anaesth Analg 2012; 39: 9198.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3. Campoy L, Martin-Flores M, Ludders JW, et al. Procedural sedation combined with locoregional anesthesia for orthopedic surgery of the pelvic limb in 10 dogs: case series. Vet Anaesth Analg 2012; 39: 436440.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 4. Cremer J, Sum SO, Braun C, et al. Assessment of maxillary and infraorbital nerve blockade for rhinoscopy in sevoflurane anesthetized dogs. Vet Anaesth Analg 2013; 40: 432439.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5. Duke T. Local and regional anesthetic and analgesic techniques in the dog and cat: part II, infiltration and nerve blocks. Can Vet J 2000; 41: 949952.

    • Search Google Scholar
    • Export Citation
  • 6. Frank ER. Dental anesthesia in the dog. J Am Vet Med Assoc 1928; 73: 232233.

  • 7. Gross ME, Pope ER, O'Brien D, et al. Regional anesthesia of the infraorbital and inferior alveolar nerves during noninvasive tooth pulp stimulation in halothane-anesthetized dogs. J Am Vet Med Assoc 1997; 211: 14031405.

    • Search Google Scholar
    • Export Citation
  • 8. Evans HE, de Lahunta A. Miller's anatomy of the dog. 4th ed. St Louis: Elsevier, 2013.

  • 9. Snyder CJ, Snyder LB. Effect of mepivacaine in an infraorbital nerve block on minimum alveolar concentration of isoflurane in clinically normal anesthetized dogs undergoing a modified form of dental dolorimetry. J Am Vet Med Assoc 2013; 242: 199204.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10. Krug W, Losey J. Area of desensitization following mental nerve blocks in dogs. J Vet Dent 2011; 28: 146150.

  • 11. Cuvillon P, Nouvellon E, Ripart J, et al. A comparison of the pharmacodynamics and pharmacokinetics of bupivacaine, ropivacaine (with epinephrine) and their equal volume mixtures with lidocaine used for femoral and sciatic nerve blocks: a double-blind randomized study. Anesth Analg 2009; 108: 641649.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 12. Vesal N, Ahmadi M, Foroud M, et al. Caudal epidural anti-nociception using lidocaine, bupivacaine or their combination in cows undergoing reproductive procedures. Vet Anaesth Analg 2013; 40: 328332.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 13. Kigozi G, Musoke R, Anyokorit M, et al. Use of a mixture of lignocaine and bupivacaine vs lignocaine alone for male circumcision under local anaesthesia in Rakai, Uganda. BJU Int 2012; 109: 10681071.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 14. Whalen LR. Electrophysiologic studies of the facial reflexes of the dog. Am J Vet Res 1985; 46: 229234.

  • 15. Kovačič U, Tesovnik B, Molnar N, et al. Dental pulp and gingivomucosa in rats are innervated by two morphologically and neurochemically different populations of nociceptors. Arch Oral Biol 2013; 58: 788795.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 16. Viscasillas J, Seymour CJ, Brodbelt DC. A cadaver study comparing two approaches for performing maxillary nerve block in dogs. Vet Anaesth Analg 2013; 40: 212219.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 17. Muir WW, Hubbell D, Bednarski B, et al. Handbook of veterinary anesthesia. 5th ed. St Louis: Elsevier, 2013.

  • 18. Beckman B, Legendre L. Regional nerve blocks for oral surgery in companion animals. Compend Contin Educ Pract Vet 2002; 24: 439444.

    • Search Google Scholar
    • Export Citation
  • 19. Atanassoff PG, Weiss BM, Brull SJ, et al. Compound motor action potential recording distinguishes differential onset of motor block of the obturator nerve in response to etidocaine or bupivacaine. Anesth Analg 1996; 82: 317320.

    • Search Google Scholar
    • Export Citation

Advertisement