1. Lemp MA, Wolfley DE. The lacrimal apparatus. In: Hart WM Jr, ed. Adler's physiology of the eye. 9th ed. Philadelphia: Mosby Year Book, 1992; 18–28.
2. Storey ES, Carboni DA, Kearney MT, et al. Use of phenol red thread tests to evaluate tear production in clinically normal Amazon parrots and comparison with Schirmer tear test findings. J Am Vet Med Assoc 2009; 235: 1181–1187.
3. Williams D. Ophthalmology. In: Ritchie BW, Harrison GJ, Harrison LR, eds. Avian medicine: principles and application. Lake Worth, Fla: Wingers Publishing, 1994; 673–694.
4. Brown MH, Brightman AH, Butine MD, et al. The phenol red thread tear test in healthy cats. Vet Comp Ophthalmol 1997; 7: 249–252.
5. Lange RR, Lima L, Montiani-Ferreira F. Measurement of tear production in black-tufted marmosets (Callithrix penicillata) using three different methods: modified Schirmer's I, phenol red thread and standardized endodontic absorbent paper points. Vet Ophthalmol 2012; 15: 376–382.
6. Wiggs RB, Lobprise HB. Basic endodontic therapy. In: Wiggs RB, Lobprise HB, eds. Veterinary dentistry: principles and practice. Philadelphia: Lippincott Raven, 1997; 280–324.
7. Brunson DB. Anesthesia in ophthalmic surgery. Vet Clin North Am Small Anim Pract 1980; 10: 481–495.
8. Brooks DE. Glaucoma in the dog and cat. Vet Clin North Am Small Anim Pract 1990; 20: 775–797.
9. Bedford PG. The aetiology of canine glaucoma. Vet Rec 1980; 107: 76–82.
10. Lange RR, Lima L, Przydzimirski AC, et al. Reference values for the production of the aqueous fraction of the tear film measured by the standardized endodontic absorbent paper point test in different exotic and laboratory animal species. Vet Ophthalmol 2014; 17: 41–45.
11. Trost K, Skalicky M, Nell B. Schirmer tear test, phenol red thread tear test, eye blink frequency and corneal sensitivity in the guinea pig. Vet Ophthalmol 2007; 10: 143–146.
12. Ofri R, Horowitz I, Kass PH. Tear production in three captive wild herbivores. Isr J Wildl Dis 1999; 35: 134–136.
13. Rajaei SM, Sadjadi R, Sabzevari A, et al. Results of phenol red thread test in clinically normal Syrian hamsters (Mesocricetus auratus). Vet Ophthalmol 2013; 16: 436–439.
14. Van der Woerdt A, Adamcak A. Comparison of absorptive capacities of original and modified Schirmer tear test strips in dogs. J Am Vet Med Assoc 2000; 216: 1576–1577.
15. da Silva EG, Sandmeyer LS, Gionfriddo JR. Tear production in canine neonates—evaluation using a modified Schirmer tear test. Vet Ophthalmol 2013; 16: 175–179.
16. Korbel R, Leitenstorfer P. The modified Schirmer tear test in birds—a method for checking lacrimal gland function. Tierarztl Prax Ausg K Klientiere Heimtiere 1998; 26: 284–294.
17. Jaax GP, Graham RR, Rozmiarek H. The Schirmer tear test in rhesus monkeys (Macaca mulatta). Lab Anim Sci 1984; 34: 293–294.
18. Somma AT, Lima L, Lange RR, et al. The eye of the red-eared slider turtle: morphologic observations and reference values for selected ophthalmic diagnostic tests. Vet Ophthalmol 2015; 18 (suppl 1): 61–70.
19. Williams DL. Analysis of tear uptake by the Schirmer tear test strip in the canine eye. Vet Ophthalmol 2005; 8: 325–330.
20. Wang WH, Millar JC, Pang IH, et al. Noninvasive measurement of rodent intraocular pressure with a rebound tonometer. Invest Ophthalmol Vis Sci 2005; 46: 4617–4621.
21. Pereira FQ, Bercht BS, Soares MG, et al. Comparison of a rebound and an applanation tonometer for measuring intraocular pressure in normal rabbits. 2011; 14: 321–326.
22. Ben-Shlomo G, Slutts LA, Ferdig JM, et al. Estimation of intraocular pressure in chinchillas utilizing rebound and applanation tonometry, in Proceedings. 45th Annu Meet Am College Vet Ophthalmol 2014; E31–E49.
23. Delgado C, Mans C, McLellan GJ, et al. Evaluation of rebound tonometry in red-eared slider turtles (Trachemys scripta elegans). Vet Ophthalmol 2014; 17: 261–267.
24. Leiva M, Naranjo C, Peña MT. Comparison of the rebound tonometer (ICare®) to the applanation tonometer (Tonopen XL®) in normotensive dogs. Vet Ophthalmol 2006; 9: 17–21.
25. Selleri P, Di Girolamo N, Andreani V, et al. Evaluation of intraocular pressure in conscious Hermann's tortoises (Testudo hermanni) by means of rebound tonometry. Am J Vet Res 2012; 73: 1807–1812.
26. Gum GG, Gelatt KN, Ofri O. Physiology of the eye. In: Gelatt KN, ed. Veterinary ophthalmology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 1999; 151–181.
27. Holt E, Rosenthal K, Shofer FS. The phenol red thread tear test in large Psittaciformes. Vet Ophthalmol 2006; 9: 109–113.
Advertisement
OBJECTIVE To determine values for tear production, horizontal palpebral fissure length (HPFL), eye blink frequency, and intraocular pressure (IOP) in healthy Syrian hamsters (Mesocricetus auratus).
ANIMALS 40 healthy adult Syrian hamsters (80 eyes).
PROCEDURES Tear production was measured with the phenol red thread test (PRTT), modified Schirmer tear test (mSTT), and endodontic absorbent paper points tear test (EAPPTT). The IOP was measured by use of rebound tonometry. Correlations between test results and body weight were evaluated.
RESULTS Mean ± SD values for the IOP, PRTT, EAPPTT, mSTT, HPFL, and blink frequency for all 80 eyes were 4.55 ± 1.33 mm Hg, 5.57 ± 1.51 mm/15 s, 4.52 ± 1.55 mm/min, 2.07 ± 0.97 mm/min, 5.84 ± 0.45 mm, and 1.68 ± 0.43 blinks/min, respectively. For all variables, values did not differ significantly between the right and left eyes or between males and females. There was no correlation between measured variables and body weight.
CONCLUSIONS AND CLINICAL RELEVANCE Results for this study provided information on values for the IOP, PRTT, mSTT, EAPPTT, HPFL, and eye blink frequency in healthy Syrian hamsters. It was important to determine reference intervals for this species because they commonly are kept as pets or used as research animals.
Dr. Rajaei's present address is Department of Clinical Sciences, College of Veterinary Medicine, Karaj Branch, Islamic Azad University, Alborz, Iran.