Comparison of cardiac output determined by an ultrasound velocity dilution cardiac output method and by the lithium dilution cardiac output method in juvenile horses with experimentally induced hypovolemia
Search for other papers by Andre C. Shih in
Current site
Google Scholar
PubMed
Search for other papers by Patricia Queiroz in
Current site
Google Scholar
PubMed
Search for other papers by Alessio Vigani in
Current site
Google Scholar
PubMed
Search for other papers by Anderson Da Cunha in
Current site
Google Scholar
PubMed
Search for other papers by Romain Pariaut in
Current site
Google Scholar
PubMed
Search for other papers by Carolina Ricco in
Current site
Google Scholar
PubMed
Search for other papers by Jennifer Bornkamp in
Current site
Google Scholar
PubMed
Search for other papers by Fernando Garcia-Pereira in
Current site
Google Scholar
PubMed
Search for other papers by Carsten Bandt in
Current site
Google Scholar
PubMed
Abstract
Objective—To assess the accuracy of an ultrasound velocity dilution cardiac output (UDCO) method, compared with that of the lithium dilution cardiac output (LiDCO) method, for determination of cardiac output (CO) in juvenile horses with experimentally induced hypovolemia.
Animals—12 anesthetized 2- to 6-month-old horses.
Procedures—For each anesthetized horse, CO was determined by the LiDCO and UDCO methods prior to any intervention (baseline state), after withdrawal of approximately 40% of the horse's blood volume (low CO state), after maintenance of hypovolemia and infusion of norepinephrine until mean arterial blood pressure was equal to baseline value (high CO state), and after further infusion of norepinephrine and back-transfusion of withdrawn blood (posttransfusion state). For each of the 4 hemodynamic situations, CO and calculated cardiac index (CI) values were obtained by each method in duplicate (8 pairs of measurements/horse); mean values for each horse and overall mean values across all horses were calculated. Agreement between CI determined by each method (96 paired values) was assessed by Bland-Altman analysis.
Results—For the UDCO method–derived CI measurements among the 12 horses, mean ± SD bias was −4 ± 11.3 mL/kg/min (95% limits of agreement, −26.1 to 18.2 mL/kg/min) and mean relative bias was −10.4 ± 21.5% (95% limits of agreement, −52.6% to 31.8%).
Conclusions and Clinical Relevance—Results indicated that, compared with the LiDCO method, the UDCO method has acceptable clinical usefulness for determination of CO in foals.
| All Time | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 29 | 0 | 0 |
| Full Text Views | 1751 | 1259 | 170 |
| PDF Downloads | 260 | 100 | 2 |
