Temporality of early-term abortions associated with mare reproductive loss syndrome in horses

Noah D. Cohen Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4475.

Search for other papers by Noah D. Cohen in
Current site
Google Scholar
PubMed
Close
 VMD, PhD
,
Vincent J. Carey Channing Laboratory, Harvard Medical School, Harvard University, Boston, MA 02115.

Search for other papers by Vincent J. Carey in
Current site
Google Scholar
PubMed
Close
 PhD
,
James G. Donahue 3640 Sequoia Trail, Verona, WI 53593.

Search for other papers by James G. Donahue in
Current site
Google Scholar
PubMed
Close
 DVM, PhD
,
Janyce L. Seahorn Livestock Disease Diagnostic Center, University of Kentucky, Lexington, KY 40511-1280.

Search for other papers by Janyce L. Seahorn in
Current site
Google Scholar
PubMed
Close
 DVM, MS
,
Stuart E. Brown II Hagyard- Davidson-McGee Associates, 4250 Iron Works Pike, Lexington, KY 40511-8491.

Search for other papers by Stuart E. Brown II in
Current site
Google Scholar
PubMed
Close
 DVM
, and
Thomas W. Riddle Rood & Riddle Equine Hospital, PO Box 12070, Lexington, KY 40580-2070.

Search for other papers by Thomas W. Riddle in
Current site
Google Scholar
PubMed
Close
 DVM

Abstract

Objective—To characterize the temporality of dates of breeding and abortion classified as mare reproductive loss syndrome (MRLS) among mares with abortions during early gestation.

Animals—2,314 mares confirmed pregnant at approximately 28 days after breeding from 36 farms in central Kentucky, including 515 mares that had earlyterm abortions.

Procedure—Farm veterinarians and managers were interviewed to obtain data for each mare that was known to be pregnant to determine pregnancy status, breeding date, last date known to be pregnant, and date of abortion.

Results—Mares bred prior to April 1, 2001, appeared to be at greatest risk of early-term abortion, both among and within individual farms. Mares bred in mid-February appeared to be at greatest risk of abortion, with an estimated weekly incidence rate of abortion of 66% (95% CI, 52% to 80%).

Conclusions and Clinical Relevance—Mares in central Kentucky bred between mid-February and early March were observed to be at greatest risk of early-term abortion, and risk gradually decreased to a background incidence of abortion of approximately 11%. Mares bred after April 1, 2001, appeared to be at markedly less risk, indicating that exposure to the cause of MRLS likely occurred prior to this date. (Am J Vet Res 2005;66:1792–1797)

Abstract

Objective—To characterize the temporality of dates of breeding and abortion classified as mare reproductive loss syndrome (MRLS) among mares with abortions during early gestation.

Animals—2,314 mares confirmed pregnant at approximately 28 days after breeding from 36 farms in central Kentucky, including 515 mares that had earlyterm abortions.

Procedure—Farm veterinarians and managers were interviewed to obtain data for each mare that was known to be pregnant to determine pregnancy status, breeding date, last date known to be pregnant, and date of abortion.

Results—Mares bred prior to April 1, 2001, appeared to be at greatest risk of early-term abortion, both among and within individual farms. Mares bred in mid-February appeared to be at greatest risk of abortion, with an estimated weekly incidence rate of abortion of 66% (95% CI, 52% to 80%).

Conclusions and Clinical Relevance—Mares in central Kentucky bred between mid-February and early March were observed to be at greatest risk of early-term abortion, and risk gradually decreased to a background incidence of abortion of approximately 11%. Mares bred after April 1, 2001, appeared to be at markedly less risk, indicating that exposure to the cause of MRLS likely occurred prior to this date. (Am J Vet Res 2005;66:1792–1797)

All Time Past Year Past 30 Days
Abstract Views 28 0 0
Full Text Views 768 660 24
PDF Downloads 110 51 2
Advertisement